| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.136664 |
| FMN1 | formin 1 | 0.105051 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0888103 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0863461 |
| TLE4 | transducin-like enhancer of split 4 | 0.0833878 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0794419 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0731763 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0717635 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0703298 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0645564 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0619746 |
| PLAT | plasminogen activator, tissue | 0.0615817 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0611385 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0588065 |
| MED13 | mediator complex subunit 13 | 0.0573936 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0564973 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0552566 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0548983 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.054252 |
| MED13L | mediator complex subunit 13-like | 0.0539988 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0528068 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0522677 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0502366 |
| FRMD5 | FERM domain containing 5 | 0.0501084 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.048421 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0472841 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0469072 |
| NDRG1 | N-myc downstream regulated 1 | 0.0465731 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0465535 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0461135 |
| SYT1 | synaptotagmin I | 0.0461106 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0455853 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0448597 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0447048 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.044326 |
| SMYD3 | SET and MYND domain containing 3 | 0.0441797 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0436902 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0436598 |
| SMAD3 | SMAD family member 3 | 0.0434312 |
| DST | dystonin | 0.0425549 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0415786 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0407483 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0406866 |
| NF1 | neurofibromin 1 | 0.040436 |
| PARD3 | par-3 family cell polarity regulator | 0.0400125 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0397202 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.039433 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0394227 |
| CCNY | cyclin Y | 0.0388793 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0385811 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0385144 |
| RPL4 | ribosomal protein L4 | 0.0377371 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0375213 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0372485 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0366074 |
| ACTG1 | actin gamma 1 | 0.0365721 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0363291 |
| RBM26 | RNA binding motif protein 26 | 0.0361243 |
| MSI2 | musashi RNA-binding protein 2 | 0.0360275 |
| TRIB2 | tribbles pseudokinase 2 | 0.0359541 |
| CRH | corticotropin releasing hormone | 0.0353304 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0352346 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0346697 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0344714 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0340874 |
| CTBP2 | C-terminal binding protein 2 | 0.0337242 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0336527 |
| FAM13A | family with sequence similarity 13, member A | 0.0333077 |
| RPS24 | ribosomal protein S24 | 0.0331731 |
| MRTFA | myocardin related transcription factor A | 0.0331485 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0328498 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0326572 |
| RPL26 | ribosomal protein L26 | 0.0325378 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0325125 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.032477 |
| MYO6 | myosin VI | 0.032293 |
| ENAH | enabled homolog (Drosophila) | 0.0320973 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0311593 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0305304 |
| PTK2 | protein tyrosine kinase 2 | 0.0305033 |
| HELZ | helicase with zinc finger | 0.0304068 |
| AFF4 | AF4/FMR2 family, member 4 | 0.030226 |
| PDE10A | phosphodiesterase 10A | 0.0301793 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0301417 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0298662 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0297503 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0296182 |
| HMGA2 | high mobility group AT-hook 2 | 0.0294565 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.029259 |
| YTHDC1 | YTH domain containing 1 | 0.0290864 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0290071 |
| AHNAK | AHNAK nucleoprotein | 0.0287879 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0287443 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0285844 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0285648 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0284956 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0281089 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0280274 |
| MYO10 | myosin X | 0.0280082 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0277035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.16436 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114048 |
| MEIS2 | Meis homeobox 2 | -0.09045 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0669156 |
| LSAMP | limbic system-associated membrane protein | -0.0448238 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0430025 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0420947 |
| RPL23 | ribosomal protein L23 | -0.0399902 |
| EGR1 | early growth response 1 | -0.0375832 |
| RPS27 | ribosomal protein S27 | -0.0375451 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0369967 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0355611 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0350193 |
| RPLP1 | ribosomal protein, large, P1 | -0.0349241 |
| POTEF | POTE ankyrin domain family, member F | -0.0332349 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.031346 |
| GOLGB1 | golgin B1 | -0.0307427 |
| GATA3 | GATA binding protein 3 | -0.028592 |
| RPS23 | ribosomal protein S23 | -0.0284397 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0282633 |
| KLHL13 | kelch-like family member 13 | -0.0282539 |
| FN1 | fibronectin 1 | -0.028248 |
| RPS19 | ribosomal protein S19 | -0.027567 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0270765 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0264319 |
| GSE1 | Gse1 coiled-coil protein | -0.0261461 |
| UBAP2 | ubiquitin associated protein 2 | -0.0260275 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0259147 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0251311 |
| MATR3 | matrin 3 | -0.0247143 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.024695 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0245098 |
| VCAN | versican | -0.0242293 |
| RPS6 | ribosomal protein S6 | -0.0242038 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0238426 |
| RPS5 | ribosomal protein S5 | -0.0235617 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0235066 |
| RGS5 | regulator of G-protein signaling 5 | -0.0232447 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.023091 |
| ZNF207 | zinc finger protein 207 | -0.0228454 |
| PKM | pyruvate kinase, muscle | -0.0227644 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0226448 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0224402 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0222229 |
| TMSB10 | thymosin beta 10 | -0.0221519 |
| SIK3 | SIK family kinase 3 | -0.0219069 |
| S100A9 | S100 calcium binding protein A9 | -0.0215453 |
| SMAD6 | SMAD family member 6 | -0.0214565 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.021385 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0209539 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0209024 |
| MAP4 | microtubule-associated protein 4 | -0.0208155 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.020799 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0205996 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0205916 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0202734 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0197077 |
| RPL36 | ribosomal protein L36 | -0.0192968 |
| HDLBP | high density lipoprotein binding protein | -0.0192796 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0190232 |
| SUMF1 | sulfatase modifying factor 1 | -0.01896 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0189404 |
| CNTN4 | contactin 4 | -0.0188381 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0188055 |
| B2M | beta-2-microglobulin | -0.0187938 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | -0.0187555 |
| RPS2 | ribosomal protein S2 | -0.0186963 |
| CHLSN | cholesin | -0.018677 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0186202 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0185149 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0183419 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0183356 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.018041 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0180327 |
| MAGT1 | magnesium transporter 1 | -0.0179356 |
| MEF2D | myocyte enhancer factor 2D | -0.0179096 |
| RPS15 | ribosomal protein S15 | -0.0178247 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0178014 |
| ATP10D | ATPase, class V, type 10D | -0.0177204 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0176821 |
| MAP1B | microtubule-associated protein 1B | -0.0176141 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0173424 |
| MKI67 | marker of proliferation Ki-67 | -0.017339 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.0173152 |
| CLIC4 | chloride intracellular channel 4 | -0.017309 |
| ZNF827 | zinc finger protein 827 | -0.0171671 |
| SEM1 | SEM1 26S proteasome subunit | -0.0171381 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0171192 |
| VIM | vimentin | -0.0171187 |
| DACH2 | dachshund family transcription factor 2 | -0.0170115 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0170083 |
| MDM4 | MDM4, p53 regulator | -0.0170047 |
| COMMD10 | COMM domain containing 10 | -0.0169633 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0169261 |
| TMEM87A | transmembrane protein 87A | -0.016804 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | -0.0167437 |
| BBX | bobby sox homolog (Drosophila) | -0.0166823 |
| RPL35 | ribosomal protein L35 | -0.0164556 |
| DENND1B | DENN/MADD domain containing 1B | -0.0163449 |
| RPS20 | ribosomal protein S20 | -0.0163039 |
