| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.157817 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.101894 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0895497 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0876694 |
| COL6A3 | collagen, type VI, alpha 3 | 0.078866 |
| NLGN1 | neuroligin 1 | 0.0785368 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0766569 |
| LDHA | lactate dehydrogenase A | 0.0745917 |
| FN1 | fibronectin 1 | 0.0700044 |
| VCL | vinculin | 0.063099 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0626963 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0603897 |
| HLA-B | major histocompatibility complex, class I, B | 0.0602008 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0549011 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0503129 |
| PTK2 | protein tyrosine kinase 2 | 0.0502303 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0492028 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.047042 |
| HIP1 | huntingtin interacting protein 1 | 0.0455195 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0450366 |
| RIGI | RNA sensor RIG-I | 0.0427689 |
| FGF13 | fibroblast growth factor 13 | 0.0415991 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0404042 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0389899 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0387399 |
| HLA-A | major histocompatibility complex, class I, A | 0.0386651 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0380377 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0374092 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0372029 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0370769 |
| WWOX | WW domain containing oxidoreductase | 0.0366687 |
| HMGA2 | high mobility group AT-hook 2 | 0.0359131 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0356725 |
| ANLN | anillin, actin binding protein | 0.0355926 |
| SFTPA2 | surfactant protein A2 | 0.0355053 |
| ACTG1 | actin gamma 1 | 0.0349271 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0348166 |
| SDC4 | syndecan 4 | 0.0347092 |
| CLIC4 | chloride intracellular channel 4 | 0.0343746 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0342905 |
| ASPH | aspartate beta-hydroxylase | 0.0333128 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0323345 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0322201 |
| DST | dystonin | 0.0321064 |
| KYNU | kynureninase | 0.0319065 |
| FAM20C | family with sequence similarity 20, member C | 0.0314908 |
| NAV1 | neuron navigator 1 | 0.0312573 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.031235 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0304392 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0297111 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0296807 |
| CEP128 | centrosomal protein 128kDa | 0.0296533 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.029596 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0294169 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0294051 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0292174 |
| FMNL2 | formin-like 2 | 0.0290513 |
| RRM2 | ribonucleotide reductase M2 | 0.0285982 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0285939 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0282383 |
| GLCCI1 | glucocorticoid induced 1 | 0.0281677 |
| NAV2 | neuron navigator 2 | 0.0274216 |
| SPAG9 | sperm associated antigen 9 | 0.0271693 |
| B2M | beta-2-microglobulin | 0.0270936 |
| ECE1 | endothelin converting enzyme 1 | 0.0268266 |
| XYLT1 | xylosyltransferase I | 0.0267454 |
| RPL23 | ribosomal protein L23 | 0.0267207 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0264581 |
| INTS6 | integrator complex subunit 6 | 0.0264045 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0263577 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0263174 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0263027 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.026278 |
| MCL1 | myeloid cell leukemia 1 | 0.0262148 |
| SVIL | supervillin | 0.0259219 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0257479 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.0244901 |
| MRC2 | mannose receptor, C type 2 | 0.0244616 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0244519 |
| C1S | complement component 1, s subcomponent | 0.0244251 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0242648 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0242192 |
| VIM | vimentin | 0.0241581 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0241573 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0240923 |
| MYO1E | myosin IE | 0.0240775 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0240072 |
| RUNX1 | runt-related transcription factor 1 | 0.023636 |
| CD44 | CD44 molecule (Indian blood group) | 0.0233949 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0232068 |
| LMO7 | LIM domain 7 | 0.0230521 |
| APP | amyloid beta (A4) precursor protein | 0.0230285 |
| DENND1A | DENN/MADD domain containing 1A | 0.0229819 |
| AGO2 | argonaute RISC catalytic component 2 | 0.022864 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.02284 |
| GRAMD1B | GRAM domain containing 1B | 0.0226616 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0222728 |
| RACK1 | receptor for activated C kinase 1 | 0.0222619 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.0222199 |
| SATB2 | SATB homeobox 2 | 0.0221302 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.192195 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.16142 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.118721 |
| FTL | ferritin, light polypeptide | -0.0957845 |
| GOLGA4 | golgin A4 | -0.0834125 |
| AHNAK | AHNAK nucleoprotein | -0.073506 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0732168 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.072922 |
| NDRG1 | N-myc downstream regulated 1 | -0.0679549 |
| GOLGB1 | golgin B1 | -0.0678732 |
| SBF2 | SET binding factor 2 | -0.0606387 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.057761 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0560508 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0505867 |
| EGFR | epidermal growth factor receptor | -0.0501171 |
| LOX | lysyl oxidase | -0.0494938 |
| MT1X | metallothionein 1X | -0.0492084 |
| RPLP1 | ribosomal protein, large, P1 | -0.0481255 |
| TNNC1 | troponin C type 1 (slow) | -0.0458435 |
| ANKRD17 | ankyrin repeat domain 17 | -0.040671 |
| SCFD2 | sec1 family domain containing 2 | -0.0406407 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0394572 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0391024 |
| ATP13A3 | ATPase type 13A3 | -0.039038 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0388169 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0384296 |
| TMSB10 | thymosin beta 10 | -0.0384274 |
| VEGFA | vascular endothelial growth factor A | -0.0383073 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0366082 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0359051 |
| COPA | coatomer protein complex, subunit alpha | -0.0358156 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0353655 |
| CANX | calnexin | -0.0351263 |
| PKM | pyruvate kinase, muscle | -0.0343565 |
| CADM1 | cell adhesion molecule 1 | -0.0338238 |
| MAP1B | microtubule-associated protein 1B | -0.0335662 |
| USP47 | ubiquitin specific peptidase 47 | -0.0335357 |
| RPL35A | ribosomal protein L35a | -0.0325966 |
| LRRC49 | leucine rich repeat containing 49 | -0.0324529 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0320887 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0317072 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0308594 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.0305188 |
| GOLGA3 | golgin A3 | -0.0304581 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0303226 |
| COG5 | component of oligomeric golgi complex 5 | -0.030016 |
| BRD4 | bromodomain containing 4 | -0.0299812 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0293019 |
| LIMA1 | LIM domain and actin binding 1 | -0.0292849 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0286429 |
| URI1 | URI1, prefoldin-like chaperone | -0.0284018 |
| HDLBP | high density lipoprotein binding protein | -0.0283237 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0278502 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0278038 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0276257 |
| SEC24D | SEC24 family member D | -0.0273969 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0273665 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0273137 |
| PHF14 | PHD finger protein 14 | -0.0271854 |
| RPS2 | ribosomal protein S2 | -0.0269612 |
| HELZ | helicase with zinc finger | -0.026852 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | -0.0261064 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0258195 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0258048 |
| DCLK2 | doublecortin-like kinase 2 | -0.0256049 |
| GSK3B | glycogen synthase kinase 3 beta | -0.025528 |
| RPS25 | ribosomal protein S25 | -0.025428 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0247444 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | -0.0247008 |
| ZNF292 | zinc finger protein 292 | -0.0246934 |
| CLINT1 | clathrin interactor 1 | -0.0246842 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0245544 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0244945 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0243474 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0243338 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0241754 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0239948 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0239659 |
| RPL37A | ribosomal protein L37a | -0.023886 |
| FAF2 | Fas associated factor family member 2 | -0.0238839 |
| RBAK-RBAKDN | RBAK-RBAKDN readthrough | -0.0235293 |
| MAP4 | microtubule-associated protein 4 | -0.0231632 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.022724 |
| GNAS | GNAS complex locus | -0.0226552 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0225918 |
| GPR107 | G protein-coupled receptor 107 | -0.0224856 |
| TXNIP | thioredoxin interacting protein | -0.0223602 |
| FNBP4 | formin binding protein 4 | -0.0223383 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0219195 |
| SRP54 | signal recognition particle 54kDa | -0.0216474 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0214816 |
| RPL18 | ribosomal protein L18 | -0.0213882 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0212801 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0212187 |
| TMEM39A | transmembrane protein 39A | -0.0212174 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0211767 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0210938 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0210533 |
| TRAM1 | translocation associated membrane protein 1 | -0.0209938 |
| RNF216 | ring finger protein 216 | -0.0209444 |
