| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.122642 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.113204 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0801312 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0629581 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0571498 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0568772 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0526797 |
| SMYD3 | SET and MYND domain containing 3 | 0.051823 |
| RRM2 | ribonucleotide reductase M2 | 0.0515627 |
| PRELID2 | PRELI domain containing 2 | 0.0498995 |
| INTS6 | integrator complex subunit 6 | 0.0497292 |
| ATXN1 | ataxin 1 | 0.0466231 |
| WWOX | WW domain containing oxidoreductase | 0.0431987 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.04317 |
| MED13L | mediator complex subunit 13-like | 0.0425903 |
| LDHA | lactate dehydrogenase A | 0.0418266 |
| FHIT | fragile histidine triad | 0.041634 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0409586 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0408827 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0400766 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0387267 |
| MCL1 | myeloid cell leukemia 1 | 0.0376268 |
| UTRN | utrophin | 0.0371877 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.035739 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.035512 |
| USP34 | ubiquitin specific peptidase 34 | 0.0352605 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0350762 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0349428 |
| APP | amyloid beta (A4) precursor protein | 0.0345376 |
| GPHN | gephyrin | 0.0336685 |
| SMAD3 | SMAD family member 3 | 0.0324804 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0321096 |
| MACROD2 | MACRO domain containing 2 | 0.0320516 |
| VCL | vinculin | 0.0316428 |
| ZNF638 | zinc finger protein 638 | 0.031624 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0314436 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0311896 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0309075 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0305804 |
| RPL4 | ribosomal protein L4 | 0.0303732 |
| ASPH | aspartate beta-hydroxylase | 0.0303356 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0299331 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0298488 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0297829 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0293993 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0291195 |
| MYO1D | myosin ID | 0.0286905 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0283449 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0279113 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0274775 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0273326 |
| DIAPH1 | diaphanous-related formin 1 | 0.0271526 |
| LRRC23 | leucine rich repeat containing 23 | 0.0269838 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0267818 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0266571 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0266296 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0264864 |
| HOMER1 | homer scaffolding protein 1 | 0.0264547 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0263774 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0262366 |
| SSH2 | slingshot protein phosphatase 2 | 0.0259745 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0255868 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0255113 |
| PCBP2 | poly(rC) binding protein 2 | 0.0254789 |
| SP100 | SP100 nuclear antigen | 0.0253586 |
| WWC1 | WW and C2 domain containing 1 | 0.0250758 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0249689 |
| VMP1 | vacuole membrane protein 1 | 0.0245737 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.024448 |
| NEBL | nebulette | 0.0243489 |
| B2M | beta-2-microglobulin | 0.0240862 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0239624 |
| EXOC6B | exocyst complex component 6B | 0.0238647 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0237983 |
| AFDN | afadin, adherens junction formation factor | 0.0236103 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0233669 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0233665 |
| ADD1 | adducin 1 (alpha) | 0.0233318 |
| TJP1 | tight junction protein 1 | 0.023229 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0231374 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0230614 |
| KRT8 | keratin 8, type II | 0.0229748 |
| RCOR1 | REST corepressor 1 | 0.0229743 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0229028 |
| DST | dystonin | 0.0228572 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0227017 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0226667 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0226361 |
| STK24 | serine/threonine kinase 24 | 0.0224739 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0221527 |
| RPS12 | ribosomal protein S12 | 0.0220978 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0220618 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0219788 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0218365 |
| OGA | O-GlcNAcase | 0.0217846 |
| PARD3 | par-3 family cell polarity regulator | 0.0217512 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.0217277 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0217044 |
| PTK2 | protein tyrosine kinase 2 | 0.021271 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0211554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.147664 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.130134 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125648 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0989322 |
| NDRG1 | N-myc downstream regulated 1 | -0.0953142 |
| TMSB10 | thymosin beta 10 | -0.0924782 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0631478 |
| GOLGA4 | golgin A4 | -0.0588967 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.051754 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0507424 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.047756 |
| PKM | pyruvate kinase, muscle | -0.0427725 |
| FAT1 | FAT atypical cadherin 1 | -0.0427014 |
| MKI67 | marker of proliferation Ki-67 | -0.0423726 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0408965 |
| WASF2 | WAS protein family, member 2 | -0.0400008 |
| RPL35A | ribosomal protein L35a | -0.0364308 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0361136 |
| CENPF | centromere protein F, 350/400kDa | -0.0347915 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0336801 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0331219 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0330721 |
| S100A6 | S100 calcium binding protein A6 | -0.0322683 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0319564 |
| RPS6 | ribosomal protein S6 | -0.0315882 |
| HDLBP | high density lipoprotein binding protein | -0.0314783 |
| KRT19 | keratin 19, type I | -0.0313276 |
| ARF4 | ADP-ribosylation factor 4 | -0.0312252 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0304435 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0297395 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0296023 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0285363 |
| OSBP | oxysterol binding protein | -0.0278193 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0277196 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0265069 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0263082 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.026211 |
| PFN1 | profilin 1 | -0.025869 |
| CANX | calnexin | -0.0250593 |
| TBC1D4 | TBC1 domain family, member 4 | -0.0247771 |
| WDR45B | WD repeat domain 45B | -0.0244777 |
| SETD5 | SET domain containing 5 | -0.0244214 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0236033 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0233137 |
| SRP54 | signal recognition particle 54kDa | -0.0221587 |
| GNAS | GNAS complex locus | -0.0219086 |
| PRDX2 | peroxiredoxin 2 | -0.0218659 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0217603 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.021651 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0215576 |
| KRT18 | keratin 18, type I | -0.0210658 |
| ITGB4 | integrin, beta 4 | -0.0209571 |
| RNF43 | ring finger protein 43 | -0.0208934 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0208699 |
| MLEC | malectin | -0.0207789 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.020734 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0204901 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0204386 |
| RPS19 | ribosomal protein S19 | -0.0201441 |
| HLA-A | major histocompatibility complex, class I, A | -0.0201259 |
| RPL8 | ribosomal protein L8 | -0.0197798 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0194639 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0191583 |
| TMF1 | TATA element modulatory factor 1 | -0.0191042 |
| FAM162A | family with sequence similarity 162, member A | -0.0189303 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0188931 |
| THRAP3 | thyroid hormone receptor associated protein 3 | -0.0187672 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0187372 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0183967 |
| TXNIP | thioredoxin interacting protein | -0.0183921 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0183199 |
| VEGFA | vascular endothelial growth factor A | -0.0182985 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0180085 |
| SEC24D | SEC24 family member D | -0.0178989 |
| OLA1 | Obg-like ATPase 1 | -0.0177799 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0177446 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0177193 |
| FTL | ferritin, light polypeptide | -0.0176925 |
| MYOF | myoferlin | -0.0175336 |
| RPL34 | ribosomal protein L34 | -0.0174054 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0173302 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0173066 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0172755 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0171827 |
| SEC24A | SEC24 family member A | -0.0171782 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0171695 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0170287 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0169315 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0169301 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0169114 |
| TPX2 | TPX2, microtubule-associated | -0.016875 |
| ARF1 | ADP-ribosylation factor 1 | -0.0168414 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0166893 |
| EGR1 | early growth response 1 | -0.0166786 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0165041 |
| GOLGA2 | golgin A2 | -0.0164129 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0163844 |
| UBE4B | ubiquitination factor E4B | -0.0163546 |
| RAD50 | RAD50 homolog (S. cerevisiae) | -0.0162331 |
| ENO1 | enolase 1, (alpha) | -0.0161458 |
