| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.126152 |
| PRELID2 | PRELI domain containing 2 | 0.116111 |
| ACTG1 | actin gamma 1 | 0.104242 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0974685 |
| MACROD2 | MACRO domain containing 2 | 0.0803073 |
| WWOX | WW domain containing oxidoreductase | 0.0789307 |
| SMAD3 | SMAD family member 3 | 0.077956 |
| TJP1 | tight junction protein 1 | 0.0732115 |
| FHIT | fragile histidine triad | 0.0684869 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0680785 |
| RUNX1 | runt-related transcription factor 1 | 0.0622606 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0612625 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0592485 |
| RAD51B | RAD51 paralog B | 0.0562106 |
| ECT2 | epithelial cell transforming 2 | 0.054978 |
| WWC1 | WW and C2 domain containing 1 | 0.0546463 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0542589 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0540722 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0519327 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0515851 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0504416 |
| OGA | O-GlcNAcase | 0.0502512 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0489913 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0476966 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0464594 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0460154 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0451325 |
| SPAG9 | sperm associated antigen 9 | 0.0450254 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0449052 |
| INTS6 | integrator complex subunit 6 | 0.0443376 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0441458 |
| VCL | vinculin | 0.0441376 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0432088 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0427022 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0425915 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0410716 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0403997 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0401624 |
| SQSTM1 | sequestosome 1 | 0.0396219 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0388989 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0381479 |
| ANLN | anillin, actin binding protein | 0.0366158 |
| ANXA1 | annexin A1 | 0.0362026 |
| TUSC3 | tumor suppressor candidate 3 | 0.0357701 |
| SMYD3 | SET and MYND domain containing 3 | 0.0354674 |
| SNX9 | sorting nexin 9 | 0.035463 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0352052 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0351731 |
| FAM13B | family with sequence similarity 13, member B | 0.0350842 |
| DIAPH1 | diaphanous-related formin 1 | 0.0350007 |
| JMJD1C | jumonji domain containing 1C | 0.0344835 |
| FTL | ferritin, light polypeptide | 0.0344724 |
| NUP58 | nucleoporin 58 | 0.0344709 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0343932 |
| BBX | bobby sox homolog (Drosophila) | 0.0341571 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0340325 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0339553 |
| XPO1 | exportin 1 | 0.0334427 |
| ANXA11 | annexin A11 | 0.0328874 |
| PCBP2 | poly(rC) binding protein 2 | 0.0325876 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0322387 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0318399 |
| EZR | ezrin | 0.0317913 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0316749 |
| RASA2 | RAS p21 protein activator 2 | 0.0313917 |
| AFDN | afadin, adherens junction formation factor | 0.0308705 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.030805 |
| MED13 | mediator complex subunit 13 | 0.0307924 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0307192 |
| CTBP2 | C-terminal binding protein 2 | 0.0303959 |
| RND3 | Rho family GTPase 3 | 0.0300364 |
| MED13L | mediator complex subunit 13-like | 0.0298721 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0297801 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0297146 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.029516 |
| RBM6 | RNA binding motif protein 6 | 0.0294461 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.02932 |
| SGMS2 | sphingomyelin synthase 2 | 0.0293001 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0292029 |
| RPLP0 | ribosomal protein, large, P0 | 0.029008 |
| MYO1E | myosin IE | 0.0288843 |
| RAB3IP | RAB3A interacting protein | 0.0287719 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0284534 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.028445 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0284118 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.028188 |
| HELZ | helicase with zinc finger | 0.0281254 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0280162 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0278903 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0278392 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0277625 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0276652 |
| MYO1D | myosin ID | 0.0276236 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0273627 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0272512 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0270673 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0266003 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0264881 |
| RCOR1 | REST corepressor 1 | 0.026401 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0263735 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.156405 |
| TMSB10 | thymosin beta 10 | -0.130778 |
| MT2A | metallothionein 2A | -0.108532 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101393 |
| NDRG1 | N-myc downstream regulated 1 | -0.0809658 |
| TMSB4X | thymosin beta 4, X-linked | -0.0746117 |
| PTMA | prothymosin, alpha | -0.0657318 |
| ENO1 | enolase 1, (alpha) | -0.0640989 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0591818 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0583668 |
| PKM | pyruvate kinase, muscle | -0.0514168 |
| EGFR | epidermal growth factor receptor | -0.0505225 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0483187 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0471623 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0471101 |
| VCAN | versican | -0.0448563 |
| HMGA1 | high mobility group AT-hook 1 | -0.0412367 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0370743 |
| EGR1 | early growth response 1 | -0.0357815 |
| MAP4 | microtubule-associated protein 4 | -0.0348902 |
| RPL35A | ribosomal protein L35a | -0.0345808 |
| CCND1 | cyclin D1 | -0.0343778 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0319732 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0312138 |
| GOLGA4 | golgin A4 | -0.0311598 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0298035 |
| KRT7 | keratin 7, type II | -0.0283139 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0282673 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0273317 |
| RPS6 | ribosomal protein S6 | -0.02701 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.026527 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0262891 |
| S100A9 | S100 calcium binding protein A9 | -0.0260763 |
| RPL34 | ribosomal protein L34 | -0.0257088 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0253568 |
| TCERG1 | transcription elongation regulator 1 | -0.0252671 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0252159 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0250201 |
| RPL13A | ribosomal protein L13a | -0.0248066 |
| PCED1B | PC-esterase domain containing 1B | -0.024609 |
| S100A6 | S100 calcium binding protein A6 | -0.0245309 |
| KRT18 | keratin 18, type I | -0.0240774 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0239245 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.023832 |
| ZNF609 | zinc finger protein 609 | -0.0235414 |
| MKI67 | marker of proliferation Ki-67 | -0.0232499 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0232093 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0228002 |
| S100A4 | S100 calcium binding protein A4 | -0.0227999 |
| TPM4 | tropomyosin 4 | -0.0226956 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.022546 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0222812 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0218651 |
| HKDC1 | hexokinase domain containing 1 | -0.0213957 |
| CD44 | CD44 molecule (Indian blood group) | -0.0210934 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0209972 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -0.0209678 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0206603 |
| AHNAK | AHNAK nucleoprotein | -0.0203083 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.020231 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0201015 |
| MATR3 | matrin 3 | -0.0199018 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0195422 |
| TPI1 | triosephosphate isomerase 1 | -0.0191922 |
| PLEC | plectin | -0.0191226 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0189235 |
| ANXA2 | annexin A2 | -0.0189076 |
| RASA3 | RAS p21 protein activator 3 | -0.0188761 |
| MGLL | monoglyceride lipase | -0.0188761 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0186867 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0185966 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0184854 |
| LMNA | lamin A/C | -0.018469 |
| OCIAD2 | OCIA domain containing 2 | -0.01808 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0179786 |
| ENOSF1 | enolase superfamily member 1 | -0.0179196 |
| LASP1 | LIM and SH3 protein 1 | -0.0178849 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0178595 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0177625 |
| GNAS | GNAS complex locus | -0.0177292 |
| H1-0 | H1.0 linker histone | -0.0176261 |
| VEGFA | vascular endothelial growth factor A | -0.0174697 |
| GLIS3 | GLIS family zinc finger 3 | -0.0173636 |
| TRAM1 | translocation associated membrane protein 1 | -0.0170366 |
| RACK1 | receptor for activated C kinase 1 | -0.0168499 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0168172 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0168024 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0167632 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0167522 |
| THOC2 | THO complex 2 | -0.0167365 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.0167036 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0166843 |
| ANXA4 | annexin A4 | -0.0166757 |
| KRT19 | keratin 19, type I | -0.0164182 |
| TEX10 | testis expressed 10 | -0.0164179 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0163164 |
| C19ORF33 | chromosome 19 open reading frame 33 | -0.0163 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0162338 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0161932 |
| AFAP1L1 | actin filament associated protein 1-like 1 | -0.016098 |
