| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.0936584 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0815173 |
| CD44 | CD44 molecule (Indian blood group) | 0.0805657 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0760097 |
| HMGA2 | high mobility group AT-hook 2 | 0.0707166 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0657095 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.065267 |
| MT2A | metallothionein 2A | 0.0636021 |
| COL5A1 | collagen, type V, alpha 1 | 0.063429 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0633623 |
| NDRG1 | N-myc downstream regulated 1 | 0.062708 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0624274 |
| FNDC3B | fibronectin type III domain containing 3B | 0.06092 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0604677 |
| SEPTIN9 | septin 9 | 0.0546639 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0519238 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0504018 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0496516 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.048201 |
| SMAD3 | SMAD family member 3 | 0.0462959 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.045739 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0432188 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0428381 |
| PCBP3 | poly(rC) binding protein 3 | 0.0422426 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0409033 |
| DUSP6 | dual specificity phosphatase 6 | 0.0399185 |
| CANX | calnexin | 0.0394685 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0391642 |
| LDHA | lactate dehydrogenase A | 0.0391492 |
| OGA | O-GlcNAcase | 0.0390214 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.036821 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0361995 |
| RPS12 | ribosomal protein S12 | 0.0361339 |
| ASPH | aspartate beta-hydroxylase | 0.0360767 |
| PDE10A | phosphodiesterase 10A | 0.0360766 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0356921 |
| FAM13A | family with sequence similarity 13, member A | 0.0356721 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0348787 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0348595 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0331314 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0324576 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0324186 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0322191 |
| CAPRIN2 | caprin family member 2 | 0.0321491 |
| MLPH | melanophilin | 0.031428 |
| ANGPTL4 | angiopoietin-like 4 | 0.0308124 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0304921 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0295814 |
| EFNA5 | ephrin-A5 | 0.0293903 |
| APP | amyloid beta (A4) precursor protein | 0.0289078 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.027234 |
| FLNB | filamin B, beta | 0.0268475 |
| LOX | lysyl oxidase | 0.026748 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0266346 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0256254 |
| PCBP2 | poly(rC) binding protein 2 | 0.025294 |
| RPL4 | ribosomal protein L4 | 0.0251256 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0251061 |
| IL11 | interleukin 11 | 0.024954 |
| RPS3 | ribosomal protein S3 | 0.0244763 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0244741 |
| RASA3 | RAS p21 protein activator 3 | 0.0243647 |
| PLEC | plectin | 0.0243151 |
| SFTPA2 | surfactant protein A2 | 0.0236009 |
| LOXL2 | lysyl oxidase-like 2 | 0.0235334 |
| MT1E | metallothionein 1E | 0.0234535 |
| ATP13A3 | ATPase type 13A3 | 0.0233462 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0233039 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0231764 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0226042 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0225817 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0225561 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0225171 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0223821 |
| MT1X | metallothionein 1X | 0.0221926 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0219537 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0218668 |
| ZNF292 | zinc finger protein 292 | 0.0217986 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0217924 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0217729 |
| SPAG9 | sperm associated antigen 9 | 0.0215476 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0213518 |
| RPS8 | ribosomal protein S8 | 0.0212594 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0211776 |
| RUNX1 | runt-related transcription factor 1 | 0.0211649 |
| AFDN | afadin, adherens junction formation factor | 0.0208767 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0207518 |
| DST | dystonin | 0.020746 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0206817 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0206431 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0204604 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0204295 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0203803 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0203296 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0202848 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0202685 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0202653 |
| RNF24 | ring finger protein 24 | 0.0202231 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.020202 |
| ZNF638 | zinc finger protein 638 | 0.020069 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.293464 |
| IGF2 | insulin-like growth factor 2 | -0.171969 |
| TMSB10 | thymosin beta 10 | -0.139207 |
| VIM | vimentin | -0.135472 |
| EGR1 | early growth response 1 | -0.0786908 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0672091 |
| POTEF | POTE ankyrin domain family, member F | -0.0539249 |
| CDH13 | cadherin 13 | -0.0497104 |
| ACTG1 | actin gamma 1 | -0.046507 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0412789 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0402485 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0363624 |
| PTMA | prothymosin, alpha | -0.0337637 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0319461 |
| CLMP | CXADR-like membrane protein | -0.0315657 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0313686 |
| PKM | pyruvate kinase, muscle | -0.0302973 |
| PFN1 | profilin 1 | -0.0302505 |
| MYO10 | myosin X | -0.0296428 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290678 |
| TPM1 | tropomyosin 1 (alpha) | -0.0288788 |
| HMGA1 | high mobility group AT-hook 1 | -0.0273479 |
| TPM4 | tropomyosin 4 | -0.0272961 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.02707 |
| RRBP1 | ribosome binding protein 1 | -0.0266536 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0263333 |
| CENPF | centromere protein F, 350/400kDa | -0.0260404 |
| COL1A1 | collagen, type I, alpha 1 | -0.0256208 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0251568 |
| DIAPH2 | diaphanous-related formin 2 | -0.0248468 |
| TPI1 | triosephosphate isomerase 1 | -0.0242353 |
| GNAS | GNAS complex locus | -0.0233342 |
| MSN | moesin | -0.0229502 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0221106 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0216141 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0200605 |
| NAV3 | neuron navigator 3 | -0.0193165 |
| RPL8 | ribosomal protein L8 | -0.0189343 |
| RAI14 | retinoic acid induced 14 | -0.0189027 |
| ASTN2 | astrotactin 2 | -0.0185228 |
| MAP1B | microtubule-associated protein 1B | -0.0182708 |
| IL1B | interleukin 1, beta | -0.018195 |
| RPS6 | ribosomal protein S6 | -0.0180682 |
| S100A10 | S100 calcium binding protein A10 | -0.0180315 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0178985 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0174143 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0173434 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0173203 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0172353 |
| COL6A2 | collagen, type VI, alpha 2 | -0.017014 |
| FMN1 | formin 1 | -0.016977 |
| FTL | ferritin, light polypeptide | -0.0167615 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0166865 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0164887 |
| TUBB | tubulin, beta class I | -0.0162574 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0161355 |
| RPL32 | ribosomal protein L32 | -0.0160984 |
| TMEM165 | transmembrane protein 165 | -0.0157367 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0157052 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0157002 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.015597 |
| RPS19 | ribosomal protein S19 | -0.015483 |
| RPLP1 | ribosomal protein, large, P1 | -0.0154571 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0153737 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0152967 |
| TUBB6 | tubulin, beta 6 class V | -0.0151495 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0150674 |
| RPS23 | ribosomal protein S23 | -0.0150083 |
| RPL35A | ribosomal protein L35a | -0.0149703 |
| WASF2 | WAS protein family, member 2 | -0.0147592 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0143961 |
| TAGLN2 | transgelin 2 | -0.0141725 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0141421 |
| FUS | FUS RNA binding protein | -0.0139495 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0139 |
| HMGB1 | high mobility group box 1 | -0.0138558 |
| RIN2 | Ras and Rab interactor 2 | -0.0133323 |
| S100A9 | S100 calcium binding protein A9 | -0.0132737 |
| RPL34 | ribosomal protein L34 | -0.013228 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0132272 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0130824 |
| CALD1 | caldesmon 1 | -0.013032 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0130105 |
| KIAA1549L | KIAA1549-like | -0.012896 |
| DIAPH3 | diaphanous-related formin 3 | -0.0127882 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0127228 |
| FRMD4A | FERM domain containing 4A | -0.0126955 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0126472 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0124606 |
| PRR11 | proline rich 11 | -0.0122657 |
| PLS3 | plastin 3 | -0.0122422 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0121115 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0121042 |
| RPS21 | ribosomal protein S21 | -0.0120689 |
| ATN1 | atrophin 1 | -0.0119145 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0117341 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0116264 |
| S100A2 | S100 calcium binding protein A2 | -0.0115855 |
| TMEM263 | transmembrane protein 263 | -0.0115834 |
| RPS15 | ribosomal protein S15 | -0.0115556 |
