| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.22363 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.139797 |
| CDH13 | cadherin 13 | 0.131606 |
| EXT1 | exostosin glycosyltransferase 1 | 0.126714 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.124909 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.123704 |
| COL6A3 | collagen, type VI, alpha 3 | 0.123441 |
| LDHA | lactate dehydrogenase A | 0.115754 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0989985 |
| IER3 | immediate early response 3 | 0.0895643 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0859832 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0834339 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0707644 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0696606 |
| ACTG1 | actin gamma 1 | 0.0691482 |
| ATXN1 | ataxin 1 | 0.0663317 |
| ASPH | aspartate beta-hydroxylase | 0.0624803 |
| SQSTM1 | sequestosome 1 | 0.0604787 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0592048 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0588742 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0562128 |
| FN1 | fibronectin 1 | 0.05467 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0541811 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0538314 |
| FBN1 | fibrillin 1 | 0.0519787 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0514953 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0509358 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0507802 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0472804 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0470743 |
| NAV2 | neuron navigator 2 | 0.0466447 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0442554 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0434528 |
| CANX | calnexin | 0.0429536 |
| IL6ST | interleukin 6 signal transducer | 0.0428449 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0427832 |
| CALU | calumenin | 0.0421861 |
| COL5A1 | collagen, type V, alpha 1 | 0.0420047 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0408301 |
| VIM | vimentin | 0.0406501 |
| MTDH | metadherin | 0.0405456 |
| CCNY | cyclin Y | 0.0402929 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0401451 |
| SP100 | SP100 nuclear antigen | 0.0395468 |
| STC1 | stanniocalcin 1 | 0.0388634 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0384395 |
| ADM | adrenomedullin | 0.0378808 |
| DST | dystonin | 0.0375454 |
| RIGI | RNA sensor RIG-I | 0.0373268 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0371585 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0370682 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0367581 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0366309 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0365928 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0361187 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0357138 |
| RPS3 | ribosomal protein S3 | 0.035109 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0347704 |
| GOLGB1 | golgin B1 | 0.0346411 |
| COL1A1 | collagen, type I, alpha 1 | 0.0346231 |
| AHNAK | AHNAK nucleoprotein | 0.0345449 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0340175 |
| RND3 | Rho family GTPase 3 | 0.0338298 |
| NEK10 | NIMA-related kinase 10 | 0.0335078 |
| HDAC9 | histone deacetylase 9 | 0.0334774 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0331119 |
| NAV1 | neuron navigator 1 | 0.03311 |
| VCL | vinculin | 0.0329709 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0328381 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0321935 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0319253 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0317475 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0315528 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0313109 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0313106 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0311857 |
| EGFR | epidermal growth factor receptor | 0.0306691 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0305487 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0303694 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0297714 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0296425 |
| INTS6 | integrator complex subunit 6 | 0.0295388 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0286445 |
| ANXA1 | annexin A1 | 0.0286431 |
| TPM4 | tropomyosin 4 | 0.0285554 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0285026 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0278279 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0276405 |
| JAK1 | Janus kinase 1 | 0.027463 |
| PGK1 | phosphoglycerate kinase 1 | 0.0273419 |
| APP | amyloid beta (A4) precursor protein | 0.0271465 |
| RPL37A | ribosomal protein L37a | 0.0268303 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0262568 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0260585 |
| OGA | O-GlcNAcase | 0.0258922 |
| FMNL2 | formin-like 2 | 0.0258639 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0256502 |
| COPA | coatomer protein complex, subunit alpha | 0.0255517 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0255379 |
| CDK13 | cyclin-dependent kinase 13 | 0.0255164 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.245928 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115439 |
| TMSB10 | thymosin beta 10 | -0.096297 |
| VEGFA | vascular endothelial growth factor A | -0.0776808 |
| COL1A2 | collagen, type I, alpha 2 | -0.0666712 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0665887 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0625564 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0622396 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0561997 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0525096 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0519329 |
| PKM | pyruvate kinase, muscle | -0.0488354 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0473535 |
| RPS6 | ribosomal protein S6 | -0.0464273 |
| RPL35A | ribosomal protein L35a | -0.0461601 |
| HMGA2 | high mobility group AT-hook 2 | -0.0446297 |
| ATP13A3 | ATPase type 13A3 | -0.0426027 |
| CD44 | CD44 molecule (Indian blood group) | -0.0423889 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0422809 |
| RPS19 | ribosomal protein S19 | -0.0379342 |
| POSTN | periostin, osteoblast specific factor | -0.036328 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0362697 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.036143 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0354838 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0354118 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0350405 |
| S100A9 | S100 calcium binding protein A9 | -0.0341989 |
| RPL8 | ribosomal protein L8 | -0.0335751 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0334555 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330663 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0321191 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0315006 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0314019 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0311429 |
| RPLP2 | ribosomal protein, large, P2 | -0.0310379 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0309844 |
| ZNF148 | zinc finger protein 148 | -0.0307537 |
| TPI1 | triosephosphate isomerase 1 | -0.030748 |
| LOXL2 | lysyl oxidase-like 2 | -0.0299161 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0292353 |
| GOLGA4 | golgin A4 | -0.0290264 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0289817 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0289724 |
| JAK2 | Janus kinase 2 | -0.0288371 |
| RPL36 | ribosomal protein L36 | -0.0286535 |
| MT2A | metallothionein 2A | -0.0276626 |
| PTMA | prothymosin, alpha | -0.0265195 |
| SBF2 | SET binding factor 2 | -0.0263891 |
| S100A6 | S100 calcium binding protein A6 | -0.0258322 |
| RPS21 | ribosomal protein S21 | -0.025798 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0257863 |
| TAPBP | TAP binding protein (tapasin) | -0.0255154 |
| IL6 | interleukin 6 | -0.0249153 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0248829 |
| RPL34 | ribosomal protein L34 | -0.024773 |
| FTL | ferritin, light polypeptide | -0.0241405 |
| VEGFC | vascular endothelial growth factor C | -0.0241198 |
| CCDC91 | coiled-coil domain containing 91 | -0.0226711 |
| HAS2 | hyaluronan synthase 2 | -0.0226621 |
| RPL23 | ribosomal protein L23 | -0.0219933 |
| KLF6 | Kruppel-like factor 6 | -0.0217198 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0216715 |
| MTSS1 | metastasis suppressor 1 | -0.0216399 |
| MAP1B | microtubule-associated protein 1B | -0.0216228 |
| PFN1 | profilin 1 | -0.0214525 |
| AXL | AXL receptor tyrosine kinase | -0.0212095 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0211285 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0210135 |
| NRP1 | neuropilin 1 | -0.020836 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0208035 |
| FLNA | filamin A, alpha | -0.0207893 |
| SMAD3 | SMAD family member 3 | -0.0207024 |
| RARB | retinoic acid receptor, beta | -0.0205612 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0205532 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0205153 |
| RPL28 | ribosomal protein L28 | -0.0203282 |
| MEF2A | myocyte enhancer factor 2A | -0.0202503 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0201482 |
| TPM1 | tropomyosin 1 (alpha) | -0.019875 |
| USP3 | ubiquitin specific peptidase 3 | -0.0197082 |
| TMEM165 | transmembrane protein 165 | -0.0195612 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0193152 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0188 |
| SEPTIN9 | septin 9 | -0.018621 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0185908 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0184905 |
| GSK3B | glycogen synthase kinase 3 beta | -0.018095 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0180608 |
| ZNF292 | zinc finger protein 292 | -0.0180092 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0179485 |
| CFAP96 | cilia and flagella associated protein 96 | -0.0178053 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0176347 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0174564 |
| ARRDC3 | arrestin domain containing 3 | -0.0173148 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.016917 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0169122 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0169083 |
| SRGN | serglycin | -0.0168548 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0166625 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0166572 |
