| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.14164 |
| SMAD3 | SMAD family member 3 | 0.101873 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0957875 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0675022 |
| FAT1 | FAT atypical cadherin 1 | 0.0656835 |
| EZR | ezrin | 0.0651418 |
| PDZD8 | PDZ domain containing 8 | 0.0642314 |
| BCL2L1 | BCL2-like 1 | 0.0629688 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0610801 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0600399 |
| STK24 | serine/threonine kinase 24 | 0.0599713 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.059689 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.058477 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0580875 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0571855 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0566284 |
| NTN4 | netrin 4 | 0.0549642 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.054099 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0537655 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0530747 |
| WWC1 | WW and C2 domain containing 1 | 0.050721 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0470943 |
| PLK2 | polo-like kinase 2 | 0.0460568 |
| TJP1 | tight junction protein 1 | 0.0450957 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0436012 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0435625 |
| FOXO1 | forkhead box O1 | 0.0432904 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0420531 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0415583 |
| JMJD1C | jumonji domain containing 1C | 0.0409469 |
| UTRN | utrophin | 0.0408863 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0403428 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0402534 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0400324 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0395044 |
| YAP1 | Yes-associated protein 1 | 0.0394766 |
| XPO1 | exportin 1 | 0.039468 |
| CTBP2 | C-terminal binding protein 2 | 0.0379828 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0378992 |
| FLNB | filamin B, beta | 0.0375274 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0374475 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.037445 |
| ANXA11 | annexin A11 | 0.0374367 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0367511 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0360506 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0352726 |
| PCBP2 | poly(rC) binding protein 2 | 0.0352548 |
| PTK2 | protein tyrosine kinase 2 | 0.0352412 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0344479 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0344037 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0341109 |
| SEPTIN9 | septin 9 | 0.0339758 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0336647 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0329911 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0326531 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0325113 |
| AFDN | afadin, adherens junction formation factor | 0.0324865 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0320048 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0318764 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0318079 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0313964 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0303836 |
| PTEN | phosphatase and tensin homolog | 0.0300902 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0295716 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0295598 |
| TJP2 | tight junction protein 2 | 0.0295421 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0293293 |
| TPM3 | tropomyosin 3 | 0.0288776 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0287089 |
| PRR5L | proline rich 5 like | 0.0284536 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0284185 |
| CUL3 | cullin 3 | 0.0283989 |
| CCNYL1 | cyclin Y-like 1 | 0.0283888 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0281223 |
| ECT2 | epithelial cell transforming 2 | 0.0278902 |
| CLTC | clathrin, heavy chain (Hc) | 0.027885 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0275976 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0275589 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.027374 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0273715 |
| SPAG9 | sperm associated antigen 9 | 0.027164 |
| SLTM | SAFB-like, transcription modulator | 0.0271114 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0269885 |
| PDE10A | phosphodiesterase 10A | 0.0265158 |
| SIK3 | SIK family kinase 3 | 0.0264447 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0262858 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0262113 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0260462 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0260323 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0256982 |
| OGA | O-GlcNAcase | 0.0256396 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0255411 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0253706 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0253096 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0252297 |
| SGMS2 | sphingomyelin synthase 2 | 0.0249381 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.024898 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0248774 |
| NCKAP1 | NCK-associated protein 1 | 0.0247266 |
| YTHDC1 | YTH domain containing 1 | 0.024561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRY | furry homolog (Drosophila) | -0.135788 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.115319 |
| EGR1 | early growth response 1 | -0.107087 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0961581 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0888169 |
| TMSB10 | thymosin beta 10 | -0.0884427 |
| RPLP1 | ribosomal protein, large, P1 | -0.0874386 |
| INTS6 | integrator complex subunit 6 | -0.0825107 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0803152 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0755 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0681335 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.067892 |
| RPS6 | ribosomal protein S6 | -0.0662129 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0659138 |
| NDRG1 | N-myc downstream regulated 1 | -0.0656094 |
| AGR2 | anterior gradient 2 | -0.0644557 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0635756 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0624972 |
| RPL35A | ribosomal protein L35a | -0.0615453 |
| RPL34 | ribosomal protein L34 | -0.0612051 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0601288 |
| PTMA | prothymosin, alpha | -0.060111 |
| POF1B | premature ovarian failure, 1B | -0.0589658 |
| RPL13A | ribosomal protein L13a | -0.056108 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0558978 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0558865 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0533304 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0531433 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0528774 |
| PRELID2 | PRELI domain containing 2 | -0.0518155 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0509472 |
| FTL | ferritin, light polypeptide | -0.0498848 |
| DIAPH2 | diaphanous-related formin 2 | -0.0498637 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0487013 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0479069 |
| ANXA2 | annexin A2 | -0.0471498 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0460076 |
| GOLGB1 | golgin B1 | -0.0456936 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0440185 |
| PCED1B | PC-esterase domain containing 1B | -0.0429581 |
| GNAS | GNAS complex locus | -0.0425919 |
| ACTG1 | actin gamma 1 | -0.0420261 |
| RPLP2 | ribosomal protein, large, P2 | -0.0417613 |
| MMP7 | matrix metallopeptidase 7 | -0.0416877 |
| RPS19 | ribosomal protein S19 | -0.0413072 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.040059 |
| RPS16 | ribosomal protein S16 | -0.039433 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0388721 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0385842 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0381467 |
| PGK1 | phosphoglycerate kinase 1 | -0.037942 |
| TRIB1 | tribbles pseudokinase 1 | -0.0379388 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0367474 |
| FOXO3 | forkhead box O3 | -0.036318 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0356551 |
| HDLBP | high density lipoprotein binding protein | -0.0355136 |
| RPL31 | ribosomal protein L31 | -0.0352593 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0352105 |
| RPS13 | ribosomal protein S13 | -0.0341431 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0341221 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0338937 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0334144 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.033319 |
| LAMA4 | laminin, alpha 4 | -0.0332422 |
| RPS24 | ribosomal protein S24 | -0.032951 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0326506 |
| KRT20 | keratin 20, type I | -0.0321947 |
| RNF213 | ring finger protein 213 | -0.0321815 |
| RTN3 | reticulon 3 | -0.0320623 |
| ATXN1 | ataxin 1 | -0.0302717 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0302568 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0299261 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0297056 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0296341 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0293328 |
| RPS8 | ribosomal protein S8 | -0.0287473 |
| RPL19 | ribosomal protein L19 | -0.0286521 |
| ACTN4 | actinin, alpha 4 | -0.0279445 |
| KRT19 | keratin 19, type I | -0.0275061 |
| RPS25 | ribosomal protein S25 | -0.0271803 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0271512 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0264863 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0262194 |
| WDR45B | WD repeat domain 45B | -0.0261964 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0260144 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0257967 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0256201 |
| INSIG1 | insulin induced gene 1 | -0.0256135 |
| DGKH | diacylglycerol kinase, eta | -0.025603 |
| LYZ | lysozyme | -0.0255479 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0255141 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0255125 |
| PKM | pyruvate kinase, muscle | -0.0254614 |
| SNX14 | sorting nexin 14 | -0.0253214 |
| S100A6 | S100 calcium binding protein A6 | -0.0248228 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.024308 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0242353 |
| JUN | jun proto-oncogene | -0.0241586 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0239619 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0239376 |
