| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.198492 |
| APOB | apolipoprotein B | 0.171501 |
| FN1 | fibronectin 1 | 0.107453 |
| EXT1 | exostosin glycosyltransferase 1 | 0.105086 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.102014 |
| GPC3 | glypican 3 | 0.0919944 |
| APOA2 | apolipoprotein A-II | 0.0885224 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0868791 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0864526 |
| FAM107B | family with sequence similarity 107, member B | 0.0859273 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0792663 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0738242 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0720017 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0675908 |
| DST | dystonin | 0.0670843 |
| SVIL | supervillin | 0.0645446 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0643839 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0589734 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0581543 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0550177 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0544203 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0535116 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0530359 |
| AHR | aryl hydrocarbon receptor | 0.0505707 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0496118 |
| VCL | vinculin | 0.0486573 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0459913 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0452482 |
| PTCHD4 | patched domain containing 4 | 0.0451814 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0450863 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0449694 |
| SDC4 | syndecan 4 | 0.0421676 |
| FOXP1 | forkhead box P1 | 0.0406143 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0395729 |
| FTL | ferritin, light polypeptide | 0.0375361 |
| LYZ | lysozyme | 0.0374767 |
| KRT23 | keratin 23, type I | 0.0373635 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0361539 |
| ACTG1 | actin gamma 1 | 0.035684 |
| MBNL3 | muscleblind-like splicing regulator 3 | 0.0349684 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0347915 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0341387 |
| FAT1 | FAT atypical cadherin 1 | 0.0340353 |
| TRIM26 | tripartite motif containing 26 | 0.0337722 |
| PERP | PERP, TP53 apoptosis effector | 0.0336829 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0333539 |
| FMNL2 | formin-like 2 | 0.0331784 |
| CADM1 | cell adhesion molecule 1 | 0.0330539 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0324483 |
| KIF21A | kinesin family member 21A | 0.0321117 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0305103 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0304975 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0300235 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0295518 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.029485 |
| EPAS1 | endothelial PAS domain protein 1 | 0.029395 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0284734 |
| CRY1 | cryptochrome circadian clock 1 | 0.0283411 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0277284 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0277277 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0276402 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.0274389 |
| KIF1B | kinesin family member 1B | 0.0274379 |
| LDHA | lactate dehydrogenase A | 0.0274199 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0273101 |
| RPS24 | ribosomal protein S24 | 0.0269716 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.026939 |
| RPLP0 | ribosomal protein, large, P0 | 0.0266527 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0265321 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0264064 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0263533 |
| GK | glycerol kinase | 0.0261843 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0256793 |
| TCIM | transcriptional and immune response regulator | 0.0252209 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0249231 |
| ENAH | enabled homolog (Drosophila) | 0.0249045 |
| KLF6 | Kruppel-like factor 6 | 0.0249034 |
| BPTF | bromodomain PHD finger transcription factor | 0.0242858 |
| ALPK2 | alpha-kinase 2 | 0.0241935 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0240625 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0239799 |
| IER3 | immediate early response 3 | 0.0239681 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0239103 |
| ITGAV | integrin, alpha V | 0.0238422 |
| MYO1D | myosin ID | 0.0237439 |
| MYO1E | myosin IE | 0.0236033 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.023577 |
| KALRN | kalirin, RhoGEF kinase | 0.0232929 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0232906 |
| A2M | alpha-2-macroglobulin | 0.0230806 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.022911 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.022906 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0228708 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.022856 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0227086 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0223222 |
| PALLD | palladin, cytoskeletal associated protein | 0.0223016 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0220355 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0219918 |
| RASA2 | RAS p21 protein activator 2 | 0.0215775 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.196046 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.169481 |
| TF | transferrin | -0.121279 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0848683 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0772426 |
| VEGFA | vascular endothelial growth factor A | -0.0645256 |
| DTNA | dystrobrevin, alpha | -0.0543834 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.053593 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0526608 |
| ENO1 | enolase 1, (alpha) | -0.0507599 |
| RPS6 | ribosomal protein S6 | -0.0500677 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0475789 |
| RPL3 | ribosomal protein L3 | -0.0469088 |
| RUNX1 | runt-related transcription factor 1 | -0.0453285 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0439464 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0439462 |
| PCBP2 | poly(rC) binding protein 2 | -0.0431451 |
| RPL23 | ribosomal protein L23 | -0.0429345 |
| NDRG1 | N-myc downstream regulated 1 | -0.0428059 |
| TNS1 | tensin 1 | -0.0420604 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0414219 |
| ASPH | aspartate beta-hydroxylase | -0.0407973 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.039259 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0390112 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0380593 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0354883 |
| MSI2 | musashi RNA-binding protein 2 | -0.0350027 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0348964 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0342135 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0337383 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.0334609 |
| ATP10A | ATPase, class V, type 10A | -0.0334104 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0320579 |
| RBM39 | RNA binding motif protein 39 | -0.0320454 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0317656 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0314283 |
| GOLGA4 | golgin A4 | -0.0314021 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0311762 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0307763 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0300679 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0299698 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286198 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0283023 |
| PLEC | plectin | -0.0276394 |
| MTSS1 | metastasis suppressor 1 | -0.027604 |
| STC2 | stanniocalcin 2 | -0.0275787 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0271666 |
| NGLY1 | N-glycanase 1 | -0.0270174 |
| HELZ | helicase with zinc finger | -0.0267587 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0267132 |
| ANKRD10 | ankyrin repeat domain 10 | -0.026339 |
| RPS3 | ribosomal protein S3 | -0.0263093 |
| RPL5 | ribosomal protein L5 | -0.0262145 |
| PARD3 | par-3 family cell polarity regulator | -0.0261752 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0259803 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0256672 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0255137 |
| GSE1 | Gse1 coiled-coil protein | -0.0251889 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0251314 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0249957 |
| QKI | QKI, KH domain containing, RNA binding | -0.024984 |
| RPL27 | ribosomal protein L27 | -0.0249327 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0248601 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0245955 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | -0.0244366 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0242605 |
| RPL36 | ribosomal protein L36 | -0.0241573 |
| RPL26 | ribosomal protein L26 | -0.0238502 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0237223 |
| CP | ceruloplasmin (ferroxidase) | -0.0236069 |
| FAM13A | family with sequence similarity 13, member A | -0.0235769 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0233346 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0232818 |
| FERMT1 | fermitin family member 1 | -0.02327 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0230407 |
| FOXK2 | forkhead box K2 | -0.0230237 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | -0.0229938 |
| PTK2 | protein tyrosine kinase 2 | -0.022946 |
| RPS12 | ribosomal protein S12 | -0.0227903 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0227266 |
| RPLP2 | ribosomal protein, large, P2 | -0.0226156 |
| MYO1B | myosin IB | -0.0224424 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0221795 |
| RPS16 | ribosomal protein S16 | -0.0221098 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0217718 |
| FBXO42 | F-box protein 42 | -0.0212501 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0211105 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0210909 |
| BBX | bobby sox homolog (Drosophila) | -0.0206046 |
| INSIG2 | insulin induced gene 2 | -0.0204102 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0203652 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0203245 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0201897 |
| C3 | complement component 3 | -0.0200332 |
| YBX1 | Y box binding protein 1 | -0.0200296 |
| HSPA1B | heat shock 70kDa protein 1B | -0.0197604 |
| RPS19 | ribosomal protein S19 | -0.0196947 |
| ARFGEF3 | ARFGEF family member 3 | -0.0193886 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0193491 |
| SETD5 | SET domain containing 5 | -0.0193389 |
