| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.145966 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0992632 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0978193 |
| FTL | ferritin, light polypeptide | 0.095243 |
| CD44 | CD44 molecule (Indian blood group) | 0.0825972 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0813996 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0795053 |
| AHNAK | AHNAK nucleoprotein | 0.0771502 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0725446 |
| RPS6 | ribosomal protein S6 | 0.0709513 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0661855 |
| MYO10 | myosin X | 0.0641318 |
| HMGA2 | high mobility group AT-hook 2 | 0.0584738 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0577758 |
| RTN4 | reticulon 4 | 0.05601 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0551709 |
| NDRG1 | N-myc downstream regulated 1 | 0.0547561 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0540823 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0537556 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0504774 |
| RPL27 | ribosomal protein L27 | 0.0487218 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0480941 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.047619 |
| MT2A | metallothionein 2A | 0.0474157 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0456481 |
| NAV1 | neuron navigator 1 | 0.0454533 |
| RPLP0 | ribosomal protein, large, P0 | 0.0453528 |
| SMAD3 | SMAD family member 3 | 0.0435844 |
| DST | dystonin | 0.0435438 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.04291 |
| MAP1B | microtubule-associated protein 1B | 0.0417784 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0417103 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0416708 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0415932 |
| ERBIN | erbb2 interacting protein | 0.0393995 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0378341 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0371796 |
| RUNX1 | runt-related transcription factor 1 | 0.0366477 |
| RPL4 | ribosomal protein L4 | 0.0360992 |
| ITGA6 | integrin, alpha 6 | 0.0358649 |
| MED13L | mediator complex subunit 13-like | 0.0358037 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0357154 |
| STC1 | stanniocalcin 1 | 0.0353412 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0347932 |
| POTEF | POTE ankyrin domain family, member F | 0.0345054 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0344718 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0342989 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0340906 |
| LIMA1 | LIM domain and actin binding 1 | 0.0340826 |
| INTS6 | integrator complex subunit 6 | 0.0339468 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0338826 |
| KLF12 | Kruppel-like factor 12 | 0.0336509 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0332464 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0326488 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0325718 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0319576 |
| RND3 | Rho family GTPase 3 | 0.031858 |
| RPS12 | ribosomal protein S12 | 0.0317855 |
| CCN2 | cellular communication network factor 2 | 0.0314253 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0304652 |
| YBX1 | Y box binding protein 1 | 0.0303142 |
| PARD3 | par-3 family cell polarity regulator | 0.0297254 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0296794 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0293801 |
| HMGA1 | high mobility group AT-hook 1 | 0.0291799 |
| FAT1 | FAT atypical cadherin 1 | 0.0290425 |
| JMJD1C | jumonji domain containing 1C | 0.0287167 |
| VCL | vinculin | 0.0283687 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0283599 |
| TPI1 | triosephosphate isomerase 1 | 0.0283485 |
| TXNRD1 | thioredoxin reductase 1 | 0.0279337 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278453 |
| ATXN1 | ataxin 1 | 0.0278242 |
| MYOF | myoferlin | 0.0272058 |
| TMPRSS15 | transmembrane protease, serine 15 | 0.0269693 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0268787 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0268786 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0265653 |
| CORO1C | coronin, actin binding protein, 1C | 0.0263072 |
| ARF4 | ADP-ribosylation factor 4 | 0.0262877 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0260783 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0258041 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0257584 |
| IPO7 | importin 7 | 0.0257304 |
| CCNL1 | cyclin L1 | 0.0254616 |
| PFN1 | profilin 1 | 0.0254018 |
| FLNB | filamin B, beta | 0.0250705 |
| KLF6 | Kruppel-like factor 6 | 0.0250241 |
| RPS25 | ribosomal protein S25 | 0.0249657 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0249032 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0247792 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0245346 |
| NABP1 | nucleic acid binding protein 1 | 0.0244049 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0242017 |
| PCBP2 | poly(rC) binding protein 2 | 0.0241202 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0238919 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0237602 |
| CENPF | centromere protein F, 350/400kDa | 0.0236146 |
| LDHA | lactate dehydrogenase A | 0.0236037 |
| ANXA5 | annexin A5 | 0.0235867 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | -0.221076 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.198738 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.148691 |
| MMP12 | matrix metallopeptidase 12 | -0.140318 |
| VIM | vimentin | -0.134585 |
| RPS27A | ribosomal protein S27a | -0.123236 |
| UBC | ubiquitin C | -0.120703 |
| TMSB10 | thymosin beta 10 | -0.113516 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.107762 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.080748 |
| LSAMP | limbic system-associated membrane protein | -0.0748722 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0686779 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.065475 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0637419 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0603674 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0556489 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0546735 |
| CANX | calnexin | -0.0536705 |
| WDR45B | WD repeat domain 45B | -0.0528336 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0513094 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0465782 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0460301 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.042609 |
| PTMA | prothymosin, alpha | -0.0413511 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0409453 |
| JUN | jun proto-oncogene | -0.0386486 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0372527 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0369651 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0366119 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.035336 |
| ANXA2 | annexin A2 | -0.0339853 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0335248 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0331307 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0330099 |
| SBF2 | SET binding factor 2 | -0.0329368 |
| CDH13 | cadherin 13 | -0.0325967 |
| KIAA1217 | KIAA1217 | -0.030403 |
| SAFB2 | scaffold attachment factor B2 | -0.0301512 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0300406 |
| PRKCE | protein kinase C, epsilon | -0.0292861 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0288057 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0280859 |
| ARFGEF3 | ARFGEF family member 3 | -0.0279409 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0275848 |
| ZNF804A | zinc finger protein 804A | -0.0275472 |
| APP | amyloid beta (A4) precursor protein | -0.0275203 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0274913 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.02747 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0272573 |
| NRP2 | neuropilin 2 | -0.0269134 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0269055 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0268707 |
| KYNU | kynureninase | -0.0266821 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0264971 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0260939 |
| RPL14 | ribosomal protein L14 | -0.0260013 |
| ENO1 | enolase 1, (alpha) | -0.0255032 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0252685 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0252506 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0248915 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0238398 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0235717 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0233502 |
| GOLGA4 | golgin A4 | -0.0232932 |
| GOLT1B | golgi transport 1B | -0.0232481 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0232393 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0228116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0225588 |
| WDR43 | WD repeat domain 43 | -0.0225489 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.022451 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0224466 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0224383 |
| NRF1 | nuclear respiratory factor 1 | -0.022416 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0221354 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0218245 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.021732 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0216389 |
| RPL34 | ribosomal protein L34 | -0.0216287 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.021537 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0213548 |
| MAP4 | microtubule-associated protein 4 | -0.0213263 |
| CALU | calumenin | -0.0212946 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0212124 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.020796 |
| DGKI | diacylglycerol kinase, iota | -0.0206687 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0206291 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0206094 |
| PTK2 | protein tyrosine kinase 2 | -0.0204692 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0201737 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0199354 |
| CDK14 | cyclin-dependent kinase 14 | -0.0195147 |
| RPL23 | ribosomal protein L23 | -0.0194738 |
| NAV3 | neuron navigator 3 | -0.0194597 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | -0.0193506 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0192954 |
| RBM25 | RNA binding motif protein 25 | -0.0190112 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0188276 |
| CALR | calreticulin | -0.0187475 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0185527 |
| NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | -0.0184529 |
