| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS12 | ribosomal protein S12 | 0.117619 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.112946 |
| LMO7 | LIM domain 7 | 0.102064 |
| FAT1 | FAT atypical cadherin 1 | 0.0942598 |
| EZR | ezrin | 0.0923041 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0914317 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0773603 |
| MYO1E | myosin IE | 0.0759917 |
| DSPP | dentin sialophosphoprotein | 0.0735539 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0713713 |
| LDHA | lactate dehydrogenase A | 0.0713392 |
| PCBP2 | poly(rC) binding protein 2 | 0.0703259 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0686125 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.066893 |
| INTS6 | integrator complex subunit 6 | 0.0663489 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0629378 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0591599 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0590711 |
| AHNAK | AHNAK nucleoprotein | 0.0585775 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0578518 |
| RPS3 | ribosomal protein S3 | 0.056168 |
| MUC13 | mucin 13, cell surface associated | 0.0552308 |
| MSI2 | musashi RNA-binding protein 2 | 0.0546354 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0539722 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0530229 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0496649 |
| MYO5B | myosin VB | 0.0489578 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0477912 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.047034 |
| RPL4 | ribosomal protein L4 | 0.0468287 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0466831 |
| ASPH | aspartate beta-hydroxylase | 0.0465431 |
| FRMD5 | FERM domain containing 5 | 0.0461859 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0437733 |
| OXSR1 | oxidative stress responsive 1 | 0.0434002 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0433451 |
| CTBP2 | C-terminal binding protein 2 | 0.0428284 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0426879 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.042529 |
| RPS8 | ribosomal protein S8 | 0.0425173 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0400448 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0388649 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0380514 |
| AREG | amphiregulin | 0.0374762 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0372037 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0368594 |
| EGFR | epidermal growth factor receptor | 0.0367752 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0358826 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0349673 |
| CLOCK | clock circadian regulator | 0.0348799 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0347522 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0345886 |
| RCOR1 | REST corepressor 1 | 0.0344722 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.034372 |
| SLTM | SAFB-like, transcription modulator | 0.0343505 |
| UBE3C | ubiquitin protein ligase E3C | 0.0342316 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0341924 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | 0.0341535 |
| NABP1 | nucleic acid binding protein 1 | 0.0341163 |
| DST | dystonin | 0.0338839 |
| ZNF638 | zinc finger protein 638 | 0.0337648 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0330127 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0326719 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0323229 |
| JUN | jun proto-oncogene | 0.0318892 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0318079 |
| SMAD3 | SMAD family member 3 | 0.0314677 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.031236 |
| FMNL2 | formin-like 2 | 0.031035 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.030879 |
| RPL7A | ribosomal protein L7a | 0.0300775 |
| APP | amyloid beta (A4) precursor protein | 0.0300078 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0297707 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0297547 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0295595 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0293996 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0293753 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0289914 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0287821 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0286283 |
| PGK1 | phosphoglycerate kinase 1 | 0.0284042 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0283196 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0279769 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0277611 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0277057 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0273 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0272886 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0272401 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0271879 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0268011 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0267416 |
| TC2N | tandem C2 domains, nuclear | 0.0263364 |
| UBAP2 | ubiquitin associated protein 2 | 0.0262325 |
| ACTG1 | actin gamma 1 | 0.0261238 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0261003 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0259903 |
| CCNYL1 | cyclin Y-like 1 | 0.0257169 |
| LRRC23 | leucine rich repeat containing 23 | 0.0256301 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0254088 |
| CAPRIN2 | caprin family member 2 | 0.0253916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.135559 |
| RPL34 | ribosomal protein L34 | -0.0931721 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0890019 |
| PRSS3 | protease, serine, 3 | -0.0867901 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0826479 |
| CALB1 | calbindin 1, 28kDa | -0.0808173 |
| PKP2 | plakophilin 2 | -0.0791757 |
| GOLGA4 | golgin A4 | -0.0736231 |
| RPL35A | ribosomal protein L35a | -0.0709476 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.057092 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0566633 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0565081 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0564444 |
| TXNRD1 | thioredoxin reductase 1 | -0.0543216 |
| TRIM2 | tripartite motif containing 2 | -0.053 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0506958 |
| TSPAN8 | tetraspanin 8 | -0.0490353 |
| RPS6 | ribosomal protein S6 | -0.048313 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0482489 |
| RPLP1 | ribosomal protein, large, P1 | -0.0477368 |
| PRELID2 | PRELI domain containing 2 | -0.047222 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0466843 |
| TMSB10 | thymosin beta 10 | -0.0463784 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0441743 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0428457 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0428302 |
| RRBP1 | ribosome binding protein 1 | -0.0424999 |
| ETNK1 | ethanolamine kinase 1 | -0.0418445 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.041567 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.041462 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0414232 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0404241 |
| ACTN4 | actinin, alpha 4 | -0.0385484 |
| PTMA | prothymosin, alpha | -0.038261 |
| PCDHB16 | protocadherin beta 16 | -0.0372454 |
| SHROOM3 | shroom family member 3 | -0.0369477 |
| RPS21 | ribosomal protein S21 | -0.0365637 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0361658 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.035373 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0352736 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0349969 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0348194 |
| ABHD17C | abhydrolase domain containing 17C | -0.0348092 |
| WWC1 | WW and C2 domain containing 1 | -0.0346981 |
| SNX9 | sorting nexin 9 | -0.0345602 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0337364 |
| DSG3 | desmoglein 3 | -0.0334717 |
| ANXA2 | annexin A2 | -0.0332651 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0325323 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0323755 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0317229 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0312954 |
| ATXN1 | ataxin 1 | -0.0312487 |
| FERMT1 | fermitin family member 1 | -0.0310919 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0310265 |
| RPS24 | ribosomal protein S24 | -0.0308893 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0308838 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0308144 |
| PDE8A | phosphodiesterase 8A | -0.0308117 |
| RTN4 | reticulon 4 | -0.0305522 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0304381 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0301283 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0300222 |
| COG5 | component of oligomeric golgi complex 5 | -0.0294584 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0294302 |
| MKI67 | marker of proliferation Ki-67 | -0.0291545 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0290669 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.02865 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0284457 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0284439 |
| HMGA1 | high mobility group AT-hook 1 | -0.028187 |
| RIGI | RNA sensor RIG-I | -0.0280664 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0275837 |
| PTEN | phosphatase and tensin homolog | -0.0274406 |
| USP3 | ubiquitin specific peptidase 3 | -0.0269343 |
| VCL | vinculin | -0.0268137 |
| CCPG1 | cell cycle progression 1 | -0.0266922 |
| RFX7 | regulatory factor X, 7 | -0.0266461 |
| PLAC8 | placenta-specific 8 | -0.0265869 |
| FOXO1 | forkhead box O1 | -0.0265528 |
| NKTR | natural killer cell triggering receptor | -0.0263688 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.026304 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0262072 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0254919 |
| FHL2 | four and a half LIM domains 2 | -0.0250557 |
| WASF2 | WAS protein family, member 2 | -0.0250439 |
| FLNB | filamin B, beta | -0.0247958 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0245929 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0244748 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.024449 |
| NEK7 | NIMA-related kinase 7 | -0.0243087 |
| LAMA4 | laminin, alpha 4 | -0.0242557 |
| MATR3 | matrin 3 | -0.0241381 |
| RPS2 | ribosomal protein S2 | -0.024108 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0241078 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0239467 |
| KLF6 | Kruppel-like factor 6 | -0.0238815 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0238242 |
| EGR1 | early growth response 1 | -0.0238044 |
| ITGA6 | integrin, alpha 6 | -0.0235989 |
