| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.108216 |
| AHNAK | AHNAK nucleoprotein | 0.0641477 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0615865 |
| GRAMD1B | GRAM domain containing 1B | 0.0582862 |
| SLTM | SAFB-like, transcription modulator | 0.0554062 |
| ASPH | aspartate beta-hydroxylase | 0.0494364 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0465809 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0444561 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0433425 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0424847 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.042379 |
| LAMB3 | laminin, beta 3 | 0.0418451 |
| LAMC2 | laminin, gamma 2 | 0.0404333 |
| MT2A | metallothionein 2A | 0.0392288 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0381315 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0352306 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0350823 |
| MCL1 | myeloid cell leukemia 1 | 0.0346803 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0341516 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0340611 |
| RPS3 | ribosomal protein S3 | 0.0339258 |
| ANKRD10 | ankyrin repeat domain 10 | 0.033432 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0333962 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0331338 |
| RPL4 | ribosomal protein L4 | 0.0326331 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0303076 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.02966 |
| LAMA4 | laminin, alpha 4 | 0.0288636 |
| STC1 | stanniocalcin 1 | 0.028687 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0277148 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0271466 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0268927 |
| SMAD3 | SMAD family member 3 | 0.0267684 |
| LDHA | lactate dehydrogenase A | 0.0261429 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0255516 |
| ENO1 | enolase 1, (alpha) | 0.0248514 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0245968 |
| SMYD3 | SET and MYND domain containing 3 | 0.0244794 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0241132 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0237167 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0236963 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0234318 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0232323 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0230013 |
| RPS24 | ribosomal protein S24 | 0.0229054 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0226646 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0222401 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0222201 |
| INTS6 | integrator complex subunit 6 | 0.0221929 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0221457 |
| RAD51B | RAD51 paralog B | 0.0220141 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0219501 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.021692 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0215299 |
| GOLGB1 | golgin B1 | 0.0212747 |
| CANX | calnexin | 0.0208103 |
| RPS8 | ribosomal protein S8 | 0.0206445 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0205315 |
| LMO7 | LIM domain 7 | 0.0204993 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0204285 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0203685 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0203465 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0203416 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0202171 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0201004 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0198648 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0196987 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0196923 |
| USP34 | ubiquitin specific peptidase 34 | 0.0196146 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0195842 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0195806 |
| RNF169 | ring finger protein 169 | 0.019387 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.0192791 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0191392 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0188518 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0188441 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0187573 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0187331 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.018349 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0180393 |
| MKI67 | marker of proliferation Ki-67 | 0.0179659 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0179537 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0178306 |
| SDC4 | syndecan 4 | 0.0177786 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0176298 |
| FNIP1 | folliculin interacting protein 1 | 0.0175879 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0174512 |
| ENSA | endosulfine alpha | 0.0173783 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0171217 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0170654 |
| KIAA1328 | KIAA1328 | 0.0170562 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0170503 |
| GM2A | GM2 ganglioside activator | 0.0170294 |
| HDLBP | high density lipoprotein binding protein | 0.0168575 |
| HOMER1 | homer scaffolding protein 1 | 0.0168541 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0168028 |
| PYGL | phosphorylase, glycogen, liver | 0.0167043 |
| PLEC | plectin | 0.0164733 |
| KIAA1217 | KIAA1217 | 0.016452 |
| CUL4A | cullin 4A | 0.0163865 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.289141 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.209909 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0956726 |
| TMSB10 | thymosin beta 10 | -0.0858438 |
| NDRG1 | N-myc downstream regulated 1 | -0.0853689 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0615862 |
| PKM | pyruvate kinase, muscle | -0.0611426 |
| TMEM165 | transmembrane protein 165 | -0.0608886 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0555152 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0542194 |
| FAM13A | family with sequence similarity 13, member A | -0.0541434 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0534684 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0505147 |
| EGR1 | early growth response 1 | -0.0483311 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0446529 |
| CST3 | cystatin C | -0.0440086 |
| PDE8A | phosphodiesterase 8A | -0.0423801 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.039051 |
| RNF145 | ring finger protein 145 | -0.0381878 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0369909 |
| PTMA | prothymosin, alpha | -0.0359737 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0356648 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0354249 |
| WASF2 | WAS protein family, member 2 | -0.0351203 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0344888 |
| SEC61G | Sec61 gamma subunit | -0.0342706 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0342131 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0337668 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0304758 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0299902 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0281845 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0280268 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0271578 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0261905 |
| FTL | ferritin, light polypeptide | -0.025913 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0244185 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0243113 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0242803 |
| CES1 | carboxylesterase 1 | -0.0234748 |
| SLMAP | sarcolemma associated protein | -0.0234598 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0225634 |
| TPD52 | tumor protein D52 | -0.0224449 |
| ARRDC3 | arrestin domain containing 3 | -0.0223016 |
| SETD5 | SET domain containing 5 | -0.0221538 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0219667 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0213921 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0213779 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0208893 |
| RAB6A | RAB6A, member RAS oncogene family | -0.020858 |
| HELZ | helicase with zinc finger | -0.0207909 |
| INSIG2 | insulin induced gene 2 | -0.0206294 |
| UVRAG | UV radiation resistance associated | -0.0205847 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0200396 |
| WDR45B | WD repeat domain 45B | -0.0199679 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0199345 |
| USP3 | ubiquitin specific peptidase 3 | -0.0197321 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0196038 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0195697 |
| RPS6 | ribosomal protein S6 | -0.0195532 |
| BRD2 | bromodomain containing 2 | -0.0195124 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | -0.0195051 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0194014 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0191586 |
| S100A10 | S100 calcium binding protein A10 | -0.0190928 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0188403 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.018623 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0184269 |
| HYOU1 | hypoxia up-regulated 1 | -0.0183105 |
| NUP58 | nucleoporin 58 | -0.018218 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0178153 |
| KRT7 | keratin 7, type II | -0.0177778 |
| PFN1 | profilin 1 | -0.0170736 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0165638 |
| S100A6 | S100 calcium binding protein A6 | -0.0165497 |
| RNF24 | ring finger protein 24 | -0.0162933 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0162472 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0161484 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0161371 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0159709 |
| MYO1B | myosin IB | -0.0158081 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0158043 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | -0.0155023 |
| S100A9 | S100 calcium binding protein A9 | -0.0152181 |
| RAB10 | RAB10, member RAS oncogene family | -0.0150786 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0150504 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0148892 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0148086 |
| RIN2 | Ras and Rab interactor 2 | -0.014754 |
| TAPBP | TAP binding protein (tapasin) | -0.0146285 |
| TFG | TRK-fused gene | -0.0145037 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.014083 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0140745 |
| VEGFA | vascular endothelial growth factor A | -0.0140134 |
| CCND1 | cyclin D1 | -0.014005 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0140009 |
| DTNA | dystrobrevin, alpha | -0.0139878 |
| CAV2 | caveolin 2 | -0.0139012 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0138243 |
| STC2 | stanniocalcin 2 | -0.0138161 |
| SRP54 | signal recognition particle 54kDa | -0.0137839 |
