| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.13958 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0869391 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0816812 |
| SMAD3 | SMAD family member 3 | 0.0735536 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0663523 |
| STC1 | stanniocalcin 1 | 0.0660823 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0612331 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0592341 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0589478 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0576848 |
| ATXN1 | ataxin 1 | 0.0553761 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0536812 |
| ASPH | aspartate beta-hydroxylase | 0.0514563 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0513877 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0492143 |
| FAM107B | family with sequence similarity 107, member B | 0.0491137 |
| INTS6 | integrator complex subunit 6 | 0.0475676 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.047432 |
| RIGI | RNA sensor RIG-I | 0.0471978 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0467965 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0441999 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.043377 |
| HMGA2 | high mobility group AT-hook 2 | 0.041494 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0414517 |
| TGFB1 | transforming growth factor, beta 1 | 0.0412005 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0403831 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0396858 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0393073 |
| SP100 | SP100 nuclear antigen | 0.0389579 |
| AADAC | arylacetamide deacetylase | 0.0377036 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0376445 |
| RPL4 | ribosomal protein L4 | 0.0376245 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0369131 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0356926 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0348846 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0341049 |
| ADM | adrenomedullin | 0.0336564 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0327571 |
| NAV2 | neuron navigator 2 | 0.0317811 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0317715 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0316904 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0307672 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0307133 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0307088 |
| B2M | beta-2-microglobulin | 0.0304325 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0302366 |
| CALU | calumenin | 0.0301796 |
| YBX3 | Y box binding protein 3 | 0.0301457 |
| IL6ST | interleukin 6 signal transducer | 0.0299736 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0297863 |
| EZR | ezrin | 0.0292216 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0290537 |
| MYO10 | myosin X | 0.0289872 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0286287 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0285177 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.028395 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0279807 |
| MT2A | metallothionein 2A | 0.0279756 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0275481 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0270429 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0270049 |
| RPL11 | ribosomal protein L11 | 0.0268913 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0266788 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0264849 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0259935 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0259555 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.025934 |
| EMP1 | epithelial membrane protein 1 | 0.0258701 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0255005 |
| JUN | jun proto-oncogene | 0.0253929 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0253518 |
| SYAP1 | synapse associated protein 1 | 0.0252406 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0251189 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0249218 |
| IER3 | immediate early response 3 | 0.0243354 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.024187 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0240791 |
| RHCG | Rh family, C glycoprotein | 0.0239617 |
| LDHA | lactate dehydrogenase A | 0.0238884 |
| LOXL2 | lysyl oxidase-like 2 | 0.0237791 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.023492 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0233155 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0228587 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0225158 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0223262 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0222757 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0219452 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0216425 |
| EREG | epiregulin | 0.0215774 |
| ANXA1 | annexin A1 | 0.0215453 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0211807 |
| APP | amyloid beta (A4) precursor protein | 0.0211329 |
| MCL1 | myeloid cell leukemia 1 | 0.0211252 |
| CTBP2 | C-terminal binding protein 2 | 0.0209526 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0208667 |
| ECE1 | endothelin converting enzyme 1 | 0.020746 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0206089 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0205906 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0205648 |
| ADAR | adenosine deaminase, RNA-specific | 0.0204163 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.166139 |
| TMSB10 | thymosin beta 10 | -0.143653 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0892503 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0768015 |
| LOX | lysyl oxidase | -0.0700482 |
| NRP1 | neuropilin 1 | -0.0660455 |
| GOLGA4 | golgin A4 | -0.0641958 |
| RUNX2 | runt-related transcription factor 2 | -0.0594042 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0520745 |
| OSMR | oncostatin M receptor | -0.0503863 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0482313 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0464678 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.04391 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0429098 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0424426 |
| GLCCI1 | glucocorticoid induced 1 | -0.0418351 |
| POTEF | POTE ankyrin domain family, member F | -0.041581 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0405445 |
| FTL | ferritin, light polypeptide | -0.0387512 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.038653 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0385771 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0370782 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0370272 |
| VEGFA | vascular endothelial growth factor A | -0.0361829 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0357353 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0356239 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0354833 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0348551 |
| MEF2A | myocyte enhancer factor 2A | -0.0332413 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0329145 |
| S100A6 | S100 calcium binding protein A6 | -0.0323969 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0322254 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0320146 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0305089 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0302286 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0299627 |
| EGR1 | early growth response 1 | -0.0299058 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0296362 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | -0.0296118 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0296018 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.029578 |
| TMEM131 | transmembrane protein 131 | -0.0283424 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0282642 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0279108 |
| SRP54 | signal recognition particle 54kDa | -0.0275312 |
| RNF145 | ring finger protein 145 | -0.0273692 |
| ADD3 | adducin 3 (gamma) | -0.0271212 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0268503 |
| GPC6 | glypican 6 | -0.0266488 |
| RPL35A | ribosomal protein L35a | -0.0266279 |
| HMGA1 | high mobility group AT-hook 1 | -0.0265632 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0263728 |
| PRSS3 | protease, serine, 3 | -0.0260523 |
| CLMP | CXADR-like membrane protein | -0.0260376 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0254561 |
| PRRX1 | paired related homeobox 1 | -0.0252871 |
| PFN1 | profilin 1 | -0.0250018 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0247099 |
| VRK2 | vaccinia related kinase 2 | -0.0247024 |
| RAI14 | retinoic acid induced 14 | -0.0246281 |
| MAP1B | microtubule-associated protein 1B | -0.0244323 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0242033 |
| NBAS | neuroblastoma amplified sequence | -0.0239996 |
| AAK1 | AP2 associated kinase 1 | -0.0237607 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0236015 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0230991 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.022986 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0229146 |
| PTEN | phosphatase and tensin homolog | -0.0226364 |
| SETD5 | SET domain containing 5 | -0.0224675 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0222243 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0221511 |
| PLIN2 | perilipin 2 | -0.0220403 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0213759 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0207508 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0205671 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0205603 |
| RNF149 | ring finger protein 149 | -0.0203913 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0203898 |
| RPLP1 | ribosomal protein, large, P1 | -0.0203075 |
| ATP13A3 | ATPase type 13A3 | -0.0202712 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.020227 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0201481 |
| YBX1 | Y box binding protein 1 | -0.020125 |
| ZNF804A | zinc finger protein 804A | -0.0200734 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0200445 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0196753 |
| CAB39 | calcium binding protein 39 | -0.0196456 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0194828 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | -0.0193187 |
| LRRC49 | leucine rich repeat containing 49 | -0.0191878 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0191482 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0188285 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.0187902 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0187779 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0187198 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0187111 |
| SMAD4 | SMAD family member 4 | -0.0184957 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.018464 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0183644 |