| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.20842 |
| PM20D1 | peptidase M20 domain containing 1 | 0.20619 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.142925 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.12562 |
| FTL | ferritin, light polypeptide | 0.0995777 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0942712 |
| WWOX | WW domain containing oxidoreductase | 0.0910608 |
| ASPH | aspartate beta-hydroxylase | 0.0849606 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0843324 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0835938 |
| AHNAK | AHNAK nucleoprotein | 0.0775933 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.071645 |
| RPL4 | ribosomal protein L4 | 0.0673483 |
| MT2A | metallothionein 2A | 0.0595389 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0552894 |
| TXNRD1 | thioredoxin reductase 1 | 0.0542016 |
| FAM107B | family with sequence similarity 107, member B | 0.0538774 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0537281 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.050101 |
| LDHA | lactate dehydrogenase A | 0.0498541 |
| RPS12 | ribosomal protein S12 | 0.0495164 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0472572 |
| CAVIN1 | caveolae associated protein 1 | 0.0456449 |
| APP | amyloid beta (A4) precursor protein | 0.0450932 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0436299 |
| IER3 | immediate early response 3 | 0.043073 |
| KYNU | kynureninase | 0.0429609 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.042394 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0413445 |
| DOCK5 | dedicator of cytokinesis 5 | 0.038853 |
| RPS3 | ribosomal protein S3 | 0.0388475 |
| RPL26 | ribosomal protein L26 | 0.0375782 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0369515 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0367336 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0356422 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0342385 |
| RPLP0 | ribosomal protein, large, P0 | 0.0334642 |
| RPL23 | ribosomal protein L23 | 0.0332732 |
| RPL7 | ribosomal protein L7 | 0.0331706 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0318373 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0316696 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0316418 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0312757 |
| MCL1 | myeloid cell leukemia 1 | 0.0311691 |
| RPL19 | ribosomal protein L19 | 0.0303137 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0296757 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0294652 |
| BMP6 | bone morphogenetic protein 6 | 0.0294607 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0294088 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0292183 |
| SMAD2 | SMAD family member 2 | 0.0292097 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.028836 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0283979 |
| ATXN1 | ataxin 1 | 0.0283935 |
| GLIS3 | GLIS family zinc finger 3 | 0.0281961 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0277035 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0276696 |
| STC1 | stanniocalcin 1 | 0.0275886 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0275578 |
| RRM2 | ribonucleotide reductase M2 | 0.0271728 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.026906 |
| RPS27A | ribosomal protein S27a | 0.0265665 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0259901 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0259299 |
| RPL11 | ribosomal protein L11 | 0.0258944 |
| AHR | aryl hydrocarbon receptor | 0.0258003 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0256251 |
| DST | dystonin | 0.0256237 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0252812 |
| YBX1 | Y box binding protein 1 | 0.0250938 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0249547 |
| RPL30 | ribosomal protein L30 | 0.0249076 |
| RPS8 | ribosomal protein S8 | 0.0247456 |
| RTN4 | reticulon 4 | 0.024708 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0242797 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0242323 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0242279 |
| EXOC6B | exocyst complex component 6B | 0.0241612 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0237639 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0234156 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0231934 |
| SMYD3 | SET and MYND domain containing 3 | 0.0229979 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0229332 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0227871 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0227246 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0223543 |
| KLF6 | Kruppel-like factor 6 | 0.0222268 |
| MRTFA | myocardin related transcription factor A | 0.0220399 |
| ANXA2 | annexin A2 | 0.0219884 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0218879 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.021874 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0217515 |
| DOCK1 | dedicator of cytokinesis 1 | 0.021614 |
| ATP11A | ATPase, class VI, type 11A | 0.0211653 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0209337 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0209119 |
| RACK1 | receptor for activated C kinase 1 | 0.0209099 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0207218 |
| CYRIB | CYFIP related Rac1 interactor B | 0.020589 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0201735 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.17966 |
| IGF2 | insulin-like growth factor 2 | -0.170823 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159467 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.127087 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.120965 |
| POTEF | POTE ankyrin domain family, member F | -0.0898149 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0858706 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0810479 |
| PYGL | phosphorylase, glycogen, liver | -0.0624345 |
| TMSB10 | thymosin beta 10 | -0.0496684 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0428026 |
| TPM4 | tropomyosin 4 | -0.0379946 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0371019 |
| PFN1 | profilin 1 | -0.0341735 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0339509 |
| GOLGA4 | golgin A4 | -0.0334631 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0333147 |
| RBM25 | RNA binding motif protein 25 | -0.0319473 |
| PKM | pyruvate kinase, muscle | -0.031424 |
| HLA-B | major histocompatibility complex, class I, B | -0.0308801 |
| ERBIN | erbb2 interacting protein | -0.0307626 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0302252 |
| EGR1 | early growth response 1 | -0.0301417 |
| HLA-A | major histocompatibility complex, class I, A | -0.0298577 |
| RPS6 | ribosomal protein S6 | -0.0295039 |
| NDRG1 | N-myc downstream regulated 1 | -0.0290119 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0285554 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | -0.0275124 |
| FLNB | filamin B, beta | -0.0273436 |
| MAP1B | microtubule-associated protein 1B | -0.026624 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0248992 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0246661 |
| EGFR | epidermal growth factor receptor | -0.0240278 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0239182 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0238666 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0234808 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0227311 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0219574 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0218605 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0217459 |
| COPA | coatomer protein complex, subunit alpha | -0.0217146 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0216741 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0214378 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0214193 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0212394 |
| CDCP1 | CUB domain containing protein 1 | -0.0211452 |
| SRP54 | signal recognition particle 54kDa | -0.0206902 |
| MYADM | myeloid-associated differentiation marker | -0.0202547 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0200534 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.019767 |
| CD99 | CD99 molecule | -0.0194278 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0194106 |
| MSN | moesin | -0.0191139 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0188049 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0187164 |
| TMEM87A | transmembrane protein 87A | -0.0186794 |
| HMGA1 | high mobility group AT-hook 1 | -0.0186626 |
| LAMB1 | laminin, beta 1 | -0.0184481 |
| OPTN | optineurin | -0.0184249 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0183651 |
| VEGFA | vascular endothelial growth factor A | -0.0182733 |
| ZNF207 | zinc finger protein 207 | -0.0180331 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0177699 |
| RNF145 | ring finger protein 145 | -0.0176824 |
| STC2 | stanniocalcin 2 | -0.0175009 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0173713 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0173641 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0173585 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0171544 |
| MATR3 | matrin 3 | -0.0169603 |
| SVIL | supervillin | -0.0169086 |
| PRR16 | proline rich 16 | -0.016898 |
| CCNL1 | cyclin L1 | -0.0167713 |
| ASTN2 | astrotactin 2 | -0.0167458 |
| FMNL2 | formin-like 2 | -0.0166724 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.016633 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0162116 |
| S100A11 | S100 calcium binding protein A11 | -0.0159129 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0158928 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0158428 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0157226 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0156922 |
| NOP58 | NOP58 ribonucleoprotein | -0.0156579 |
| CA2 | carbonic anhydrase II | -0.0155327 |
| IL6 | interleukin 6 | -0.0155318 |
| HDGF | hepatoma-derived growth factor | -0.0154917 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0154659 |
| PRAME | preferentially expressed antigen in melanoma | -0.0154208 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0153716 |
| RSF1 | remodeling and spacing factor 1 | -0.0152027 |
| CFDP1 | craniofacial development protein 1 | -0.0150073 |
| TLK1 | tousled-like kinase 1 | -0.0149036 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0148086 |
| NUP58 | nucleoporin 58 | -0.0147249 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0146918 |
| LAMA5 | laminin, alpha 5 | -0.0146589 |
| ARF4 | ADP-ribosylation factor 4 | -0.0146353 |
| YY1 | YY1 transcription factor | -0.0145442 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0144829 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.014446 |
