| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.175145 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.128819 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.125836 |
| GRAMD1B | GRAM domain containing 1B | 0.0919828 |
| MCL1 | myeloid cell leukemia 1 | 0.091744 |
| YBX3 | Y box binding protein 3 | 0.0909963 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0862838 |
| WWOX | WW domain containing oxidoreductase | 0.0857234 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0848209 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0783033 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0769436 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0721863 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0714513 |
| PRELID2 | PRELI domain containing 2 | 0.0710329 |
| EXOC4 | exocyst complex component 4 | 0.0696625 |
| HMGA2 | high mobility group AT-hook 2 | 0.069338 |
| RBM39 | RNA binding motif protein 39 | 0.0674756 |
| HOMER1 | homer scaffolding protein 1 | 0.066463 |
| ACTG1 | actin gamma 1 | 0.0664596 |
| RAD51B | RAD51 paralog B | 0.0641325 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0634705 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0630209 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0623429 |
| VCL | vinculin | 0.0615112 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0598333 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0587214 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0586952 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0566193 |
| INTS6 | integrator complex subunit 6 | 0.0562628 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0549722 |
| AEBP2 | AE binding protein 2 | 0.0544281 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0536489 |
| FMNL2 | formin-like 2 | 0.0529768 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0508196 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0495364 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0487249 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0481151 |
| ATXN1 | ataxin 1 | 0.0479885 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0472735 |
| YAP1 | Yes-associated protein 1 | 0.0444376 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.044256 |
| RRM2 | ribonucleotide reductase M2 | 0.0433677 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0432999 |
| PDE10A | phosphodiesterase 10A | 0.043069 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0428029 |
| PRKCE | protein kinase C, epsilon | 0.0427548 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0427417 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0419975 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0418542 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0415245 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0408299 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0401201 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0401138 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0396363 |
| LDHA | lactate dehydrogenase A | 0.0396048 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0392018 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0387761 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0384622 |
| CUX1 | cut-like homeobox 1 | 0.037884 |
| NEK10 | NIMA-related kinase 10 | 0.0378567 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.037712 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0361267 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0360998 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0353257 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0353074 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0352723 |
| SMYD3 | SET and MYND domain containing 3 | 0.0347694 |
| CAPRIN2 | caprin family member 2 | 0.0347391 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0340529 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0339007 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0338392 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0335094 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0335016 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0334922 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0329226 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0329018 |
| RPS12 | ribosomal protein S12 | 0.032813 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0327332 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0326525 |
| TRIM59 | tripartite motif containing 59 | 0.0325577 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.03251 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0321389 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321312 |
| PCBP2 | poly(rC) binding protein 2 | 0.032059 |
| CPNE1 | copine I | 0.0319546 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0316349 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0313781 |
| BRD2 | bromodomain containing 2 | 0.0310479 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0309963 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0308006 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.030615 |
| PTK2 | protein tyrosine kinase 2 | 0.0303918 |
| DIAPH2 | diaphanous-related formin 2 | 0.0302411 |
| GPATCH2L | G patch domain containing 2-like | 0.0298534 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0296433 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0287379 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0286209 |
| BNC2 | basonuclin 2 | 0.0285966 |
| RPL9 | ribosomal protein L9 | 0.0284971 |
| ADIPOR2 | adiponectin receptor 2 | 0.0283245 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.164042 |
| EGR1 | early growth response 1 | -0.0735655 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0582157 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0464352 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0451119 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0399611 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0395625 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0383887 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0371458 |
| LATS2 | large tumor suppressor kinase 2 | -0.0365902 |
| RTN4 | reticulon 4 | -0.0357919 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0348178 |
| SBF2 | SET binding factor 2 | -0.0343285 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0337956 |
| RFX7 | regulatory factor X, 7 | -0.0335214 |
| AHNAK | AHNAK nucleoprotein | -0.0323227 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0322218 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0312575 |
| MKI67 | marker of proliferation Ki-67 | -0.0309777 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0279433 |
| TMEM165 | transmembrane protein 165 | -0.0277829 |
| ADAR | adenosine deaminase, RNA-specific | -0.0266417 |
| LIMA1 | LIM domain and actin binding 1 | -0.0266404 |
| PFN1 | profilin 1 | -0.0264932 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0256188 |
| EGFR | epidermal growth factor receptor | -0.0255394 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0253844 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0252401 |
| RPS27 | ribosomal protein S27 | -0.0252194 |
| CCND2 | cyclin D2 | -0.0249396 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0245039 |
| PNN | pinin, desmosome associated protein | -0.0241702 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0237384 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -0.0236506 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0235489 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0233058 |
| WASF2 | WAS protein family, member 2 | -0.0227554 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0226726 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0226534 |
| SIN3A | SIN3 transcription regulator family member A | -0.0226141 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0221994 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0220036 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0218641 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0217128 |
| CDCP1 | CUB domain containing protein 1 | -0.0216274 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0216167 |
| PKM | pyruvate kinase, muscle | -0.0215816 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.0214446 |
| GOLGA4 | golgin A4 | -0.0213908 |
| RAI1 | retinoic acid induced 1 | -0.0212506 |
| KMT2D | lysine (K)-specific methyltransferase 2D | -0.0210962 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0207229 |
| PTMS | parathymosin | -0.0204633 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0198204 |
| SNX9 | sorting nexin 9 | -0.0197992 |
| RNF169 | ring finger protein 169 | -0.0191733 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.018763 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0187515 |
| CLDN1 | claudin 1 | -0.0187095 |
| ZFR | zinc finger RNA binding protein | -0.0184082 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0182651 |
| PLEC | plectin | -0.0182465 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.0181733 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0181307 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0180434 |
| MRPS5 | mitochondrial ribosomal protein S5 | -0.0180116 |
| WDR35 | WD repeat domain 35 | -0.0179382 |
| IMMT | inner membrane protein, mitochondrial | -0.0178568 |
| IGF2 | insulin-like growth factor 2 | -0.0177961 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0175444 |
| TLN1 | talin 1 | -0.0175217 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.017338 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0172907 |
| TMSB10 | thymosin beta 10 | -0.0170161 |
| BSG | basigin (Ok blood group) | -0.0169611 |
| RNF38 | ring finger protein 38 | -0.0169176 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0168786 |
| ITGB5 | integrin, beta 5 | -0.0168733 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0168588 |
| RPS2 | ribosomal protein S2 | -0.0167375 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.0166035 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0165805 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0165346 |
| EPN2 | epsin 2 | -0.0163846 |
| RPLP2 | ribosomal protein, large, P2 | -0.0163774 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0163631 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0162908 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0162672 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0162369 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0162103 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0160319 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.016009 |
| CDK19 | cyclin-dependent kinase 19 | -0.0159456 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0158964 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0158768 |
| HCFC1 | host cell factor C1 | -0.0158587 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0158472 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0156904 |
| MATR3 | matrin 3 | -0.0156859 |
| GOLGB1 | golgin B1 | -0.0155812 |
