| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ALCAM | activated leukocyte cell adhesion molecule | 0.137448 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.130869 |
| EXT1 | exostosin glycosyltransferase 1 | 0.116828 |
| LMO7 | LIM domain 7 | 0.109261 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.103223 |
| AHNAK | AHNAK nucleoprotein | 0.10218 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0966539 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0940399 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0899764 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0846511 |
| LAMC2 | laminin, gamma 2 | 0.0828401 |
| MYO6 | myosin VI | 0.0771718 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0741051 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0732114 |
| ANXA2 | annexin A2 | 0.0716203 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0711968 |
| ASPH | aspartate beta-hydroxylase | 0.0703987 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0696373 |
| KRT7 | keratin 7, type II | 0.0678929 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0642243 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0629173 |
| SMAD3 | SMAD family member 3 | 0.0615466 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0614397 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0611114 |
| RASAL2 | RAS protein activator like 2 | 0.0610938 |
| RNF213 | ring finger protein 213 | 0.0591101 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0589088 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0570297 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0568589 |
| PTK2 | protein tyrosine kinase 2 | 0.0544452 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0538701 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0524634 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0523808 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0519127 |
| ERBIN | erbb2 interacting protein | 0.0518893 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0518755 |
| MYO5B | myosin VB | 0.0513927 |
| FTL | ferritin, light polypeptide | 0.0502682 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0494989 |
| RAB10 | RAB10, member RAS oncogene family | 0.0490128 |
| ATXN1 | ataxin 1 | 0.0480537 |
| DSG2 | desmoglein 2 | 0.0471442 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0471105 |
| INTS6 | integrator complex subunit 6 | 0.0466217 |
| VGLL3 | vestigial-like family member 3 | 0.0462228 |
| DSPP | dentin sialophosphoprotein | 0.04614 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0458463 |
| EGFR | epidermal growth factor receptor | 0.0455671 |
| NTN4 | netrin 4 | 0.0455325 |
| ETV6 | ets variant 6 | 0.0451689 |
| GRAMD2B | GRAM domain containing 2B | 0.0451215 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0446047 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0442444 |
| TJP1 | tight junction protein 1 | 0.044126 |
| SEPTIN11 | septin 11 | 0.0433546 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0433026 |
| MYOF | myoferlin | 0.0429534 |
| SVIL | supervillin | 0.0428642 |
| SGMS2 | sphingomyelin synthase 2 | 0.0427803 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.042589 |
| RUNX1 | runt-related transcription factor 1 | 0.0421744 |
| DST | dystonin | 0.0421587 |
| PLEC | plectin | 0.0419291 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0416596 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0409452 |
| S100A10 | S100 calcium binding protein A10 | 0.0398925 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0395197 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.039359 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0393389 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.039129 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.039122 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0388269 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0386541 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0384193 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0379715 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0378307 |
| FHIT | fragile histidine triad | 0.0377997 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0377136 |
| PGK1 | phosphoglycerate kinase 1 | 0.0374904 |
| EFNA5 | ephrin-A5 | 0.0369709 |
| RIGI | RNA sensor RIG-I | 0.0366487 |
| PTMA | prothymosin, alpha | 0.0366117 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0365949 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364183 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0363134 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.036283 |
| CTBP2 | C-terminal binding protein 2 | 0.0361538 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0360827 |
| APP | amyloid beta (A4) precursor protein | 0.0350765 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0349865 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0349246 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0347362 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0346497 |
| S100A6 | S100 calcium binding protein A6 | 0.0346454 |
| LAMB3 | laminin, beta 3 | 0.0345851 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0341998 |
| RCOR1 | REST corepressor 1 | 0.03392 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0338041 |
| PALLD | palladin, cytoskeletal associated protein | 0.0337854 |
| AREG | amphiregulin | 0.033776 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.153068 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.139499 |
| FN1 | fibronectin 1 | -0.129446 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0709953 |
| GOLGA4 | golgin A4 | -0.0602807 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0588452 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0483274 |
| RPL9 | ribosomal protein L9 | -0.0442822 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0391095 |
| CANX | calnexin | -0.0384659 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0373719 |
| RPS13 | ribosomal protein S13 | -0.036506 |
| CDCP1 | CUB domain containing protein 1 | -0.036108 |
| RPS6 | ribosomal protein S6 | -0.0357316 |
| FAM3C | family with sequence similarity 3, member C | -0.034538 |
| RPS12 | ribosomal protein S12 | -0.0343161 |
| TMEM165 | transmembrane protein 165 | -0.0329205 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0321056 |
| RPL30 | ribosomal protein L30 | -0.032017 |
| FAM13A | family with sequence similarity 13, member A | -0.0317097 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0308855 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0307206 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0295333 |
| ARRDC3 | arrestin domain containing 3 | -0.0290924 |
| RPL35A | ribosomal protein L35a | -0.0290089 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.028303 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0277192 |
| UPP1 | uridine phosphorylase 1 | -0.0275831 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.027297 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0267395 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0267194 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0265666 |
| MTDH | metadherin | -0.0254252 |
| RPS17 | ribosomal protein S17 | -0.0243549 |
| RPS23 | ribosomal protein S23 | -0.0236015 |
| ZFR | zinc finger RNA binding protein | -0.0224798 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0224302 |
| VIRMA | vir like m6A methyltransferase associated | -0.0224206 |
| TXNRD1 | thioredoxin reductase 1 | -0.0222276 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0221837 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.022182 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0220185 |
| VEGFA | vascular endothelial growth factor A | -0.0219705 |
| RACK1 | receptor for activated C kinase 1 | -0.0219143 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0217293 |
| TPM4 | tropomyosin 4 | -0.0214538 |
| HLA-B | major histocompatibility complex, class I, B | -0.0209016 |
| RPS25 | ribosomal protein S25 | -0.0207586 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0207359 |
| RPS8 | ribosomal protein S8 | -0.0199954 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0197507 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0197151 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0196401 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0194792 |
| HLA-A | major histocompatibility complex, class I, A | -0.019271 |
| RPL23 | ribosomal protein L23 | -0.019263 |
| RPLP2 | ribosomal protein, large, P2 | -0.0191258 |
| RPS19 | ribosomal protein S19 | -0.0190402 |
| RPS2 | ribosomal protein S2 | -0.0188736 |
| RPL5 | ribosomal protein L5 | -0.0186679 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0183246 |
| FBXO33 | F-box protein 33 | -0.0182246 |
| RPS27 | ribosomal protein S27 | -0.018105 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0178703 |
| RPL31 | ribosomal protein L31 | -0.0175902 |
| TMSB4X | thymosin beta 4, X-linked | -0.0174952 |
| SLMAP | sarcolemma associated protein | -0.0172313 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.0172229 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0171076 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0170262 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0169526 |
| MKRN1 | makorin ring finger protein 1 | -0.0169412 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0168387 |
| HMGA1 | high mobility group AT-hook 1 | -0.0166922 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.016556 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -0.0165371 |
| RPL37 | ribosomal protein L37 | -0.0163033 |
| RBM25 | RNA binding motif protein 25 | -0.0162779 |
| RPS27A | ribosomal protein S27a | -0.0162545 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0162151 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0161882 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0159281 |
| TRAM1 | translocation associated membrane protein 1 | -0.0158477 |
| PDCD10 | programmed cell death 10 | -0.0156763 |
| LOC112694756 | uncharaterized LOC112694756 | -0.015622 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0154867 |
| CREBRF | CREB3 regulatory factor | -0.0154668 |
| RPS15 | ribosomal protein S15 | -0.0153063 |
| MATR3 | matrin 3 | -0.0152196 |
| WDR45B | WD repeat domain 45B | -0.0150666 |
| FAM168B | family with sequence similarity 168, member B | -0.0150618 |
| TMEM41B | transmembrane protein 41B | -0.0147869 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0146878 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0145926 |
| CCNK | cyclin K | -0.0145642 |
| RPL34 | ribosomal protein L34 | -0.0145135 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0144887 |
| ADAR | adenosine deaminase, RNA-specific | -0.014405 |
| S100A9 | S100 calcium binding protein A9 | -0.0143966 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.014252 |
