| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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131 genes differentially expressed following the Norepinephrine (hydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.212076 |
| NAV2 | neuron navigator 2 | 0.167955 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.164436 |
| MYO10 | myosin X | 0.160948 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.151693 |
| RPL23 | ribosomal protein L23 | 0.150798 |
| COL6A3 | collagen, type VI, alpha 3 | 0.150503 |
| AHNAK | AHNAK nucleoprotein | 0.148332 |
| RPS8 | ribosomal protein S8 | 0.146834 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.143385 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.139138 |
| FNDC3B | fibronectin type III domain containing 3B | 0.106411 |
| NF1 | neurofibromin 1 | 0.104304 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0998334 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0880038 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0873014 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0847883 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0819567 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.076811 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0765716 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0754448 |
| OGA | O-GlcNAcase | 0.0705427 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0698532 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0678329 |
| RPS6 | ribosomal protein S6 | 0.0644573 |
| CANX | calnexin | 0.0612244 |
| PTMA | prothymosin, alpha | 0.0584893 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0574816 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0559263 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0542178 |
| TMSB10 | thymosin beta 10 | 0.0455581 |
| FAM13A | family with sequence similarity 13, member A | 0.0452208 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0447472 |
| PKM | pyruvate kinase, muscle | 0.0445254 |
| CDH13 | cadherin 13 | 0.0399313 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0318844 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.031179 |
| RPS12 | ribosomal protein S12 | 0.0305423 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0296637 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0293723 |
| PGK1 | phosphoglycerate kinase 1 | 0.0281972 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0272195 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0252509 |
| LDHA | lactate dehydrogenase A | 0.0231892 |
| SPAG9 | sperm associated antigen 9 | 0.0231492 |
| SMYD3 | SET and MYND domain containing 3 | 0.0215482 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0211244 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0193658 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0131403 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0117713 |
| MAP1B | microtubule-associated protein 1B | 0.00979268 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00886461 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00836029 |
| RPS19 | ribosomal protein S19 | 0.008283 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.00813578 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.00690734 |
| NDRG1 | N-myc downstream regulated 1 | 0.00563834 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00352831 |
| JMJD1C | jumonji domain containing 1C | 0.00259051 |
| HMGA2 | high mobility group AT-hook 2 | 4.27984E-4 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 3.47173E-4 |
| NIBAN2 | niban apoptosis regulator 2 | 6.48312E-5 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.212624 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.18859 |
| IGF2 | insulin-like growth factor 2 | -0.148204 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.127501 |
| FN1 | fibronectin 1 | -0.125159 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.121517 |
| EXT1 | exostosin glycosyltransferase 1 | -0.104289 |
| PARD3 | par-3 family cell polarity regulator | -0.0973219 |
| NPAS2 | neuronal PAS domain protein 2 | -0.091194 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0854229 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0806911 |
| GPC6 | glypican 6 | -0.0740528 |
| SBF2 | SET binding factor 2 | -0.0732591 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.069213 |
| MYO1E | myosin IE | -0.0666691 |
| GOLGA4 | golgin A4 | -0.0664922 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0640564 |
| VCL | vinculin | -0.0637529 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0611879 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0596127 |
| EFNA5 | ephrin-A5 | -0.0592307 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0555992 |
| NRG3 | neuregulin 3 | -0.0532902 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0532727 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0524795 |
| ANXA2 | annexin A2 | -0.0509689 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0504888 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0503804 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0502334 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0499326 |
| STC1 | stanniocalcin 1 | -0.0493719 |
| LMO7 | LIM domain 7 | -0.0492919 |
| VIM | vimentin | -0.0454243 |
| MCL1 | myeloid cell leukemia 1 | -0.0436248 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0387365 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0379398 |
| EGFR | epidermal growth factor receptor | -0.0365387 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0343006 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0339425 |
| HDLBP | high density lipoprotein binding protein | -0.0338451 |
| NLGN1 | neuroligin 1 | -0.0329719 |
| COL5A1 | collagen, type V, alpha 1 | -0.0322006 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0269222 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0249459 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0248905 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0244132 |
| FTL | ferritin, light polypeptide | -0.0240489 |
| EZR | ezrin | -0.0221197 |
| RPS25 | ribosomal protein S25 | -0.0220846 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0216968 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0207629 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0171041 |
| ZNF292 | zinc finger protein 292 | -0.0169717 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0165847 |
| TXNRD1 | thioredoxin reductase 1 | -0.0162054 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0130678 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0126777 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0125882 |
| PDE10A | phosphodiesterase 10A | -0.00999572 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00876688 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.00818481 |
| FAT1 | FAT atypical cadherin 1 | -0.00798971 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.00743759 |
| DSCAM | Down syndrome cell adhesion molecule | -0.00684996 |
| MT2A | metallothionein 2A | -0.0067928 |
| B2M | beta-2-microglobulin | -0.00597769 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.00564033 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00258402 |
| MYOF | myoferlin | -0.00216093 |
