| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.206019 |
| CADM2 | cell adhesion molecule 2 | 0.141511 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.121761 |
| PARD3B | par-3 family cell polarity regulator beta | 0.120344 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.115804 |
| DST | dystonin | 0.111957 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111429 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.105571 |
| PCDH9 | protocadherin 9 | 0.0999378 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0962205 |
| LRRC4C | leucine rich repeat containing 4C | 0.0935435 |
| RPS12 | ribosomal protein S12 | 0.0900816 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0781776 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0710578 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0709769 |
| TENM3 | teneurin transmembrane protein 3 | 0.0675764 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0657963 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0650942 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0608247 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0607728 |
| USP34 | ubiquitin specific peptidase 34 | 0.058327 |
| ITGAV | integrin, alpha V | 0.0558974 |
| PHIP | pleckstrin homology domain interacting protein | 0.0555425 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0537807 |
| PCBP2 | poly(rC) binding protein 2 | 0.0536808 |
| SNX6 | sorting nexin 6 | 0.0527971 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0524973 |
| NHSL1 | NHS-like 1 | 0.0521582 |
| HDAC9 | histone deacetylase 9 | 0.0508958 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0504914 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0504883 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0498806 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0497871 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0496843 |
| PCDH7 | protocadherin 7 | 0.0496454 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0483603 |
| OGA | O-GlcNAcase | 0.0463119 |
| XPO1 | exportin 1 | 0.044848 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0446719 |
| NEBL | nebulette | 0.0441456 |
| ENO1 | enolase 1, (alpha) | 0.0437492 |
| USP53 | ubiquitin specific peptidase 53 | 0.0429777 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0426718 |
| JMJD1C | jumonji domain containing 1C | 0.0424691 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0422443 |
| CALR | calreticulin | 0.0420726 |
| LDHA | lactate dehydrogenase A | 0.0419549 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0409912 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0406464 |
| ERBIN | erbb2 interacting protein | 0.0403018 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0400077 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0396175 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.039554 |
| MED13L | mediator complex subunit 13-like | 0.0394976 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0393327 |
| ZNF638 | zinc finger protein 638 | 0.0393164 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0392691 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.038194 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0375606 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0375156 |
| HMGA2 | high mobility group AT-hook 2 | 0.0371262 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0367756 |
| MYOF | myoferlin | 0.0367036 |
| RPL31 | ribosomal protein L31 | 0.0366761 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0365615 |
| RPS3 | ribosomal protein S3 | 0.0359994 |
| ATXN2 | ataxin 2 | 0.0359143 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0358138 |
| COL3A1 | collagen, type III, alpha 1 | 0.0357568 |
| RAB31 | RAB31, member RAS oncogene family | 0.0356607 |
| SRP54 | signal recognition particle 54kDa | 0.035537 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0353474 |
| SRPK2 | SRSF protein kinase 2 | 0.035297 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.035238 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0344506 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0339796 |
| RPS6 | ribosomal protein S6 | 0.0338366 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0334876 |
| PRELID2 | PRELI domain containing 2 | 0.0334326 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0333616 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0333424 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0330694 |
| PLPP1 | phospholipid phosphatase 1 | 0.0330248 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0328989 |
| HMCN1 | hemicentin 1 | 0.0327581 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0326552 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0326497 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0326442 |
| THOC2 | THO complex 2 | 0.032232 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0322301 |
| CEP192 | centrosomal protein 192kDa | 0.0322173 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0321718 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0319684 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0319578 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0319016 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0316228 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0315358 |
| BPTF | bromodomain PHD finger transcription factor | 0.0313276 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0312738 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0311553 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0893216 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0495298 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0489531 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0474148 |
| PFN1 | profilin 1 | -0.0408313 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0399967 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0392914 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | -0.0363753 |
| SYT1 | synaptotagmin I | -0.0363007 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0361651 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.03544 |
| WDR43 | WD repeat domain 43 | -0.033032 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0322408 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0298659 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0287932 |
| OLA1 | Obg-like ATPase 1 | -0.0284137 |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | -0.0281861 |
| FAM171B | family with sequence similarity 171, member B | -0.027706 |
| SPAG9 | sperm associated antigen 9 | -0.0270769 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.026944 |
| TXNRD1 | thioredoxin reductase 1 | -0.0267324 |
| MAP1B | microtubule-associated protein 1B | -0.0265236 |
| FBL | fibrillarin | -0.0264756 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0255524 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0254616 |
| THBS1 | thrombospondin 1 | -0.0247314 |
| RBBP6 | retinoblastoma binding protein 6 | -0.024503 |
| CENPF | centromere protein F, 350/400kDa | -0.0239925 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0238463 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0236801 |
| ARL13B | ADP-ribosylation factor-like 13B | -0.0235207 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0234859 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0234191 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0232351 |
| ZNF292 | zinc finger protein 292 | -0.0231684 |
| PEG10 | paternally expressed 10 | -0.0228494 |
| COL1A2 | collagen, type I, alpha 2 | -0.0227974 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0226497 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0225525 |
| DSTN | destrin (actin depolymerizing factor) | -0.0223789 |
| DEK | DEK proto-oncogene | -0.0222855 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0220528 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0218212 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0217087 |
| KIF5B | kinesin family member 5B | -0.0216537 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0215907 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0213985 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0213479 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0210267 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0209541 |
| MRTFA | myocardin related transcription factor A | -0.020944 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | -0.0207144 |
| AAK1 | AP2 associated kinase 1 | -0.0206172 |
| PLS3 | plastin 3 | -0.0202509 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.0202018 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0201861 |
| RFX7 | regulatory factor X, 7 | -0.0200955 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.020008 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0199403 |
| SLC38A2 | solute carrier family 38, member 2 | -0.019915 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0199078 |
| ATG5 | autophagy related 5 | -0.0194327 |
| MYL9 | myosin, light chain 9, regulatory | -0.0191902 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.019165 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0191482 |
| BTG3 | BTG family, member 3 | -0.0191262 |
| RAB22A | RAB22A, member RAS oncogene family | -0.018965 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0189239 |
| PURB | purine-rich element binding protein B | -0.0188462 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0188128 |
| PRR16 | proline rich 16 | -0.0188033 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0188003 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0186815 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0186562 |
| ARF1 | ADP-ribosylation factor 1 | -0.0186381 |
| RLIM | ring finger protein, LIM domain interacting | -0.0185798 |
| CHD3 | chromodomain helicase DNA binding protein 3 | -0.018479 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0182705 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.0182239 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0181669 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0179325 |
| CBX3 | chromobox homolog 3 | -0.0179032 |
| GLI3 | GLI family zinc finger 3 | -0.0177653 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0175439 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0174696 |
| POTEF | POTE ankyrin domain family, member F | -0.017468 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0173685 |
| POMP | proteasome maturation protein | -0.0172586 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.017193 |
| RPLP2 | ribosomal protein, large, P2 | -0.017001 |
| MORF4L1 | mortality factor 4 like 1 | -0.0169901 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0169131 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C | -0.0168137 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0167411 |
| TMEM50A | transmembrane protein 50A | -0.0166884 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.016666 |
| SASS6 | spindle assembly 6 homolog (C. elegans) | -0.0166507 |
| GNAS | GNAS complex locus | -0.0166026 |
| RPL19 | ribosomal protein L19 | -0.0166005 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0163792 |
