| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | 0.254711 |
| AHNAK | AHNAK nucleoprotein | 0.228353 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.145534 |
| FNDC3B | fibronectin type III domain containing 3B | 0.128972 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.113241 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.106405 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0966373 |
| SEPTIN9 | septin 9 | 0.0908931 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0879244 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0872909 |
| FBL | fibrillarin | 0.0728566 |
| DST | dystonin | 0.0724323 |
| NAV2 | neuron navigator 2 | 0.0701923 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0660878 |
| SFTPA2 | surfactant protein A2 | 0.061837 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0555962 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0546924 |
| FMNL2 | formin-like 2 | 0.0510942 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0506918 |
| MORF4L2 | mortality factor 4 like 2 | 0.0502809 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0486744 |
| MYOF | myoferlin | 0.0469702 |
| SMAD3 | SMAD family member 3 | 0.0460869 |
| SPAG9 | sperm associated antigen 9 | 0.0442095 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0439706 |
| SBF2 | SET binding factor 2 | 0.0422822 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0420969 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0407546 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0407435 |
| CTBP2 | C-terminal binding protein 2 | 0.0403278 |
| RPL35A | ribosomal protein L35a | 0.0388738 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0386109 |
| INTS6 | integrator complex subunit 6 | 0.038074 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0378277 |
| MKI67 | marker of proliferation Ki-67 | 0.0376833 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0376266 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0361758 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0351067 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0348668 |
| SNX14 | sorting nexin 14 | 0.0345782 |
| MYO10 | myosin X | 0.0340525 |
| PTMA | prothymosin, alpha | 0.033914 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0338703 |
| RPL4 | ribosomal protein L4 | 0.0334274 |
| PDE10A | phosphodiesterase 10A | 0.0330612 |
| EFNA5 | ephrin-A5 | 0.0329555 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0323691 |
| YBX1 | Y box binding protein 1 | 0.0320947 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0314999 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0309193 |
| ATP13A3 | ATPase type 13A3 | 0.0303976 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0301561 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0301523 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0299583 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292579 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.028798 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0287574 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0287437 |
| ANLN | anillin, actin binding protein | 0.0285997 |
| PRELID2 | PRELI domain containing 2 | 0.0285195 |
| RPS6 | ribosomal protein S6 | 0.0283535 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0281495 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0279077 |
| CMIP | c-Maf inducing protein | 0.0278396 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0276124 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0275878 |
| ANO6 | anoctamin 6 | 0.0274772 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.027433 |
| FAT1 | FAT atypical cadherin 1 | 0.0273593 |
| AFDN | afadin, adherens junction formation factor | 0.0272017 |
| FN1 | fibronectin 1 | 0.0270011 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0268891 |
| UBAP2 | ubiquitin associated protein 2 | 0.0267544 |
| HPCAL1 | hippocalcin-like 1 | 0.0264756 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0257294 |
| ATXN1 | ataxin 1 | 0.0257293 |
| TAOK1 | TAO kinase 1 | 0.0250943 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0246713 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0246583 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.024394 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0243275 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0239864 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0239722 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0239431 |
| PLEC | plectin | 0.0239397 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0238854 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0233127 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0232781 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0232629 |
| FNIP1 | folliculin interacting protein 1 | 0.0232618 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0229513 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.02287 |
| APP | amyloid beta (A4) precursor protein | 0.0228651 |
| RPL3 | ribosomal protein L3 | 0.0227635 |
| CDK6 | cyclin-dependent kinase 6 | 0.0226749 |
| WWC2 | WW and C2 domain containing 2 | 0.0225502 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0225182 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0222575 |
| TNS3 | tensin 3 | 0.0220288 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0219189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.26775 |
| UBC | ubiquitin C | -0.13081 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0959995 |
| RPS27A | ribosomal protein S27a | -0.0747191 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0669709 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0635355 |
| ACTN4 | actinin, alpha 4 | -0.0569896 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0454303 |
| RTN4 | reticulon 4 | -0.0421459 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0390876 |
| S100A6 | S100 calcium binding protein A6 | -0.0368643 |
| FHL2 | four and a half LIM domains 2 | -0.0350243 |
| ACTG1 | actin gamma 1 | -0.0340227 |
| EGR1 | early growth response 1 | -0.0330761 |
| VMP1 | vacuole membrane protein 1 | -0.0323723 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0321651 |
| TMEM41B | transmembrane protein 41B | -0.0321594 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0301406 |
| JUN | jun proto-oncogene | -0.0298498 |
| RPLP0 | ribosomal protein, large, P0 | -0.0294329 |
| VCL | vinculin | -0.0289438 |
| MAP1B | microtubule-associated protein 1B | -0.0279095 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0278501 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0277713 |
| ENO1 | enolase 1, (alpha) | -0.0274588 |
| MCL1 | myeloid cell leukemia 1 | -0.0264136 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0262052 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0260555 |
| FOSL1 | FOS-like antigen 1 | -0.0252452 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0246873 |
| DSTN | destrin (actin depolymerizing factor) | -0.0235577 |
| SET | SET nuclear proto-oncogene | -0.023257 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0222865 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0221771 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0213599 |
| RPL37A | ribosomal protein L37a | -0.0211553 |
| THOC2 | THO complex 2 | -0.0209421 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0209343 |
| RPS12 | ribosomal protein S12 | -0.0201135 |
| TMSB10 | thymosin beta 10 | -0.0200802 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0197051 |
| OSMR | oncostatin M receptor | -0.0195771 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0192898 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0189714 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0186574 |
| CALR | calreticulin | -0.0181417 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0180634 |
| RPL30 | ribosomal protein L30 | -0.0179975 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0174744 |
| RIGI | RNA sensor RIG-I | -0.0174064 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0172489 |
| FTL | ferritin, light polypeptide | -0.0168966 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0166935 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0166743 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0166513 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0165496 |
| MYADM | myeloid-associated differentiation marker | -0.0164027 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0162925 |
| RBM25 | RNA binding motif protein 25 | -0.0160891 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0159466 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0158512 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0157359 |
| RPS5 | ribosomal protein S5 | -0.0151628 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0151622 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | -0.0147272 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0146805 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | -0.0146419 |
| TUBA1C | tubulin, alpha 1c | -0.0146382 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0144722 |
| ZMAT2 | zinc finger, matrin-type 2 | -0.0143818 |
| TXNDC12 | thioredoxin domain containing 12 (endoplasmic reticulum) | -0.0143621 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0143262 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0142143 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.014178 |
| RPS3 | ribosomal protein S3 | -0.0141497 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0139773 |
| ZYX | zyxin | -0.0139468 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0139065 |
| H3-3B | H3.3 histone B | -0.0138854 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0133582 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0132662 |
| TMEM87A | transmembrane protein 87A | -0.0132244 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0131719 |
| TUBA1B | tubulin, alpha 1b | -0.0130483 |
| DLL3 | delta-like 3 (Drosophila) | -0.0126928 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0125417 |
| LRP11 | low density lipoprotein receptor-related protein 11 | -0.0123121 |
| RPS2 | ribosomal protein S2 | -0.0121005 |
| GOLT1A | golgi transport 1A | -0.0120738 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0120011 |
| LMO4 | LIM domain only 4 | -0.0119754 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0117665 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.011735 |
| CERS2 | ceramide synthase 2 | -0.0117113 |
| LDHA | lactate dehydrogenase A | -0.011627 |
| DEK | DEK proto-oncogene | -0.0116237 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0115696 |
| RACK1 | receptor for activated C kinase 1 | -0.0114908 |
| SESN2 | sestrin 2 | -0.0114574 |
| BCL10 | B-cell CLL/lymphoma 10 | -0.0114122 |
