| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Norepinephrine (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.129491 |
| FRMD6 | FERM domain containing 6 | 0.124591 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.122433 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.112124 |
| EXT1 | exostosin glycosyltransferase 1 | 0.110342 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.107952 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.106519 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0813599 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.080148 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0732493 |
| SGMS2 | sphingomyelin synthase 2 | 0.0726171 |
| RASA2 | RAS p21 protein activator 2 | 0.0643996 |
| SMYD3 | SET and MYND domain containing 3 | 0.059077 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0590335 |
| CAPRIN2 | caprin family member 2 | 0.0579513 |
| FMNL2 | formin-like 2 | 0.0548626 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0541734 |
| RIGI | RNA sensor RIG-I | 0.0535015 |
| RAD51B | RAD51 paralog B | 0.0532759 |
| SP100 | SP100 nuclear antigen | 0.0521587 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0516098 |
| FRMD4A | FERM domain containing 4A | 0.0510874 |
| HDAC9 | histone deacetylase 9 | 0.0507967 |
| JMJD1C | jumonji domain containing 1C | 0.0497944 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0495953 |
| NAV2 | neuron navigator 2 | 0.0495287 |
| TOP1 | topoisomerase (DNA) I | 0.0484939 |
| RCOR1 | REST corepressor 1 | 0.0484132 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0478848 |
| INTS6 | integrator complex subunit 6 | 0.0444223 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0441565 |
| UPP1 | uridine phosphorylase 1 | 0.0437324 |
| PTMA | prothymosin, alpha | 0.0436054 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0434157 |
| AHNAK | AHNAK nucleoprotein | 0.0431718 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0425898 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0408437 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0407242 |
| APP | amyloid beta (A4) precursor protein | 0.0404673 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0402648 |
| CORO1C | coronin, actin binding protein, 1C | 0.0401496 |
| STC1 | stanniocalcin 1 | 0.0397021 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0395913 |
| ANXA5 | annexin A5 | 0.0388946 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0385427 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0369819 |
| EFNB2 | ephrin-B2 | 0.0367884 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0367864 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0365894 |
| EMP1 | epithelial membrane protein 1 | 0.0362109 |
| RUNX1 | runt-related transcription factor 1 | 0.036145 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.036124 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0353212 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0353034 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0353026 |
| RAD21 | RAD21 homolog (S. pombe) | 0.035293 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0350768 |
| PTK2 | protein tyrosine kinase 2 | 0.034665 |
| PARD3 | par-3 family cell polarity regulator | 0.0344765 |
| ATP13A3 | ATPase type 13A3 | 0.0344656 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.034388 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0337389 |
| RPLP0 | ribosomal protein, large, P0 | 0.0336067 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0335717 |
| JUN | jun proto-oncogene | 0.0335304 |
| RRM2 | ribonucleotide reductase M2 | 0.0334854 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0332415 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0332269 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.033224 |
| DEK | DEK proto-oncogene | 0.0331829 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.033165 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0328796 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.032814 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0324812 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0324469 |
| CCNY | cyclin Y | 0.0324256 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0322785 |
| CUX1 | cut-like homeobox 1 | 0.0320942 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0320545 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0317558 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0317364 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0316504 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0314337 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0313289 |
| WWOX | WW domain containing oxidoreductase | 0.0311578 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0311248 |
| ADTRP | androgen-dependent TFPI-regulating protein | 0.0309069 |
| MTDH | metadherin | 0.0307426 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0304734 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0303459 |
| DIAPH3 | diaphanous-related formin 3 | 0.0299766 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0297694 |
| UBE3C | ubiquitin protein ligase E3C | 0.0297551 |
| VMP1 | vacuole membrane protein 1 | 0.0296527 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0296337 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0293394 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0292548 |
| STK4 | serine/threonine kinase 4 | 0.0290529 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0290504 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0289431 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | -0.120097 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0789452 |
| POTEF | POTE ankyrin domain family, member F | -0.0788895 |
| RPS6 | ribosomal protein S6 | -0.0778014 |
| RPLP1 | ribosomal protein, large, P1 | -0.0666001 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0594816 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0571223 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0562648 |
| LOC112694756 | uncharaterized LOC112694756 | -0.055545 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.055236 |
| RPL35A | ribosomal protein L35a | -0.0543741 |
| RPL35 | ribosomal protein L35 | -0.0526771 |
| PKM | pyruvate kinase, muscle | -0.0514052 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0491803 |
| RPL34 | ribosomal protein L34 | -0.0484772 |
| HMGA1 | high mobility group AT-hook 1 | -0.0460512 |
| GOLGA4 | golgin A4 | -0.0442042 |
| RPS2 | ribosomal protein S2 | -0.0432576 |
| RPS19 | ribosomal protein S19 | -0.0419036 |
| RPL8 | ribosomal protein L8 | -0.0408309 |
| RPS21 | ribosomal protein S21 | -0.0406756 |
| RPL28 | ribosomal protein L28 | -0.0397657 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0393411 |
| PCNX4 | pecanex 4 | -0.0384194 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0376881 |
| RPL19 | ribosomal protein L19 | -0.0375945 |
| RPS27 | ribosomal protein S27 | -0.0357961 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0349124 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0346209 |
| RPL12 | ribosomal protein L12 | -0.0344686 |
| RPL23 | ribosomal protein L23 | -0.0344034 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0343215 |
| EGR1 | early growth response 1 | -0.0341275 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0335905 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0335227 |
| TRAM1 | translocation associated membrane protein 1 | -0.0328377 |
| TMSB10 | thymosin beta 10 | -0.0320184 |
| RPS29 | ribosomal protein S29 | -0.0301632 |
| S100A2 | S100 calcium binding protein A2 | -0.0293112 |
| HLA-A | major histocompatibility complex, class I, A | -0.0291692 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0278007 |
| FLNA | filamin A, alpha | -0.0276362 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0275539 |
| RPLP2 | ribosomal protein, large, P2 | -0.0275458 |
| RPL30 | ribosomal protein L30 | -0.0274772 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | -0.0272378 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0270269 |
| RPL37 | ribosomal protein L37 | -0.0263489 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0261178 |
| RPL37A | ribosomal protein L37a | -0.02564 |
| RPL21 | ribosomal protein L21 | -0.025538 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0254678 |
| CCDC50 | coiled-coil domain containing 50 | -0.0252821 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0251457 |
| TTR | transthyretin | -0.0250425 |
| RPS23 | ribosomal protein S23 | -0.0244939 |
| PTEN | phosphatase and tensin homolog | -0.024408 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0242386 |
| RNF11 | ring finger protein 11 | -0.0238054 |
| RPS26 | ribosomal protein S26 | -0.0235706 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0234201 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0233286 |
| CALD1 | caldesmon 1 | -0.0232011 |
| PHF3 | PHD finger protein 3 | -0.0229962 |
| COG5 | component of oligomeric golgi complex 5 | -0.0225872 |
| RPL9 | ribosomal protein L9 | -0.022408 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0224026 |
| RPL7A | ribosomal protein L7a | -0.0221993 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0220718 |
| TMF1 | TATA element modulatory factor 1 | -0.0219913 |
| MATR3 | matrin 3 | -0.0217774 |
| FAM91A1 | family with sequence similarity 91, member A1 | -0.0214032 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.021368 |
| ZNF37A | zinc finger protein 37A | -0.0213586 |
| ATN1 | atrophin 1 | -0.0213109 |
| LDHB | lactate dehydrogenase B | -0.0212193 |
| TMEM165 | transmembrane protein 165 | -0.0211582 |
| RPL10A | ribosomal protein L10a | -0.0207907 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0205481 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0202003 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0199026 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0199019 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | -0.0197263 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.0194844 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0194333 |
| GUK1 | guanylate kinase 1 | -0.0192151 |
| RPL3 | ribosomal protein L3 | -0.019078 |
| PGAM4 | phosphoglycerate mutase family member 4 | -0.0188772 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0188041 |
| ETNK1 | ethanolamine kinase 1 | -0.0188017 |
| SEC24D | SEC24 family member D | -0.0186498 |
| CALR | calreticulin | -0.0185159 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0184516 |
| SLC41A1 | solute carrier family 41 (magnesium transporter), member 1 | -0.0182271 |
| EPHA2 | EPH receptor A2 | -0.0180599 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 | -0.0179475 |
| TXNRD1 | thioredoxin reductase 1 | -0.0178178 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0177423 |
| FOSL1 | FOS-like antigen 1 | -0.0176045 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0174655 |
