| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.139311 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.124147 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.114584 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0940345 |
| SMAD3 | SMAD family member 3 | 0.0891866 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0775694 |
| CD44 | CD44 molecule (Indian blood group) | 0.0714219 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0634771 |
| LDHA | lactate dehydrogenase A | 0.0631385 |
| RUNX1 | runt-related transcription factor 1 | 0.0625167 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0622894 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0620091 |
| NAV2 | neuron navigator 2 | 0.059184 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0589304 |
| VIM | vimentin | 0.0584067 |
| DST | dystonin | 0.0581267 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0559146 |
| FAT1 | FAT atypical cadherin 1 | 0.052199 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0514552 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0512746 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0507585 |
| HLA-B | major histocompatibility complex, class I, B | 0.0505027 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0499236 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0495024 |
| B2M | beta-2-microglobulin | 0.0491178 |
| FNIP1 | folliculin interacting protein 1 | 0.0462511 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0457833 |
| CLIC4 | chloride intracellular channel 4 | 0.045133 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0421072 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0398302 |
| INHBA | inhibin, beta A | 0.0397179 |
| ECE1 | endothelin converting enzyme 1 | 0.0395707 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0389518 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0387317 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0378545 |
| AHNAK | AHNAK nucleoprotein | 0.0376526 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0374722 |
| IL1B | interleukin 1, beta | 0.0373385 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0371268 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0369592 |
| HLA-A | major histocompatibility complex, class I, A | 0.0369178 |
| USP34 | ubiquitin specific peptidase 34 | 0.0364717 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0357111 |
| FHIT | fragile histidine triad | 0.0353237 |
| SQSTM1 | sequestosome 1 | 0.0347119 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0340782 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0339657 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0338561 |
| JUN | jun proto-oncogene | 0.0331743 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.031983 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0313638 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0312435 |
| FBXO32 | F-box protein 32 | 0.0309877 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0304566 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0304458 |
| AFDN | afadin, adherens junction formation factor | 0.0303675 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0303239 |
| IER3 | immediate early response 3 | 0.0300524 |
| RBM39 | RNA binding motif protein 39 | 0.0297652 |
| ANGPTL4 | angiopoietin-like 4 | 0.0297136 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0296622 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0292933 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0292851 |
| MYOF | myoferlin | 0.0291311 |
| BRD2 | bromodomain containing 2 | 0.0288785 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0288527 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0288488 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0287183 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0286633 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0284045 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0282112 |
| IL6ST | interleukin 6 signal transducer | 0.0281577 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0280682 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0280558 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0279081 |
| KIAA1217 | KIAA1217 | 0.0278938 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0278245 |
| PLAT | plasminogen activator, tissue | 0.0277156 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0276095 |
| SP100 | SP100 nuclear antigen | 0.0268435 |
| ANXA2 | annexin A2 | 0.0267653 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0266824 |
| SH3PXD2B | SH3 and PX domains 2B | 0.0265962 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0264504 |
| SMYD3 | SET and MYND domain containing 3 | 0.0263418 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0263407 |
| SON | SON DNA binding protein | 0.026268 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0261115 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0260358 |
| PGK1 | phosphoglycerate kinase 1 | 0.0260283 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0259933 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0255617 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0254693 |
| SVIL | supervillin | 0.0253022 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0252989 |
| MCL1 | myeloid cell leukemia 1 | 0.0250013 |
| WWOX | WW domain containing oxidoreductase | 0.0249663 |
| XPO1 | exportin 1 | 0.0249563 |
| FRMD5 | FERM domain containing 5 | 0.0249386 |
| YBX1 | Y box binding protein 1 | 0.0248382 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A1 | collagen, type VI, alpha 1 | -0.0880815 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0838542 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0732338 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0729653 |
| FN1 | fibronectin 1 | -0.0692798 |
| MT2A | metallothionein 2A | -0.0672363 |
| TMSB10 | thymosin beta 10 | -0.0654754 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0651261 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0603462 |
| NDRG1 | N-myc downstream regulated 1 | -0.0588555 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0497212 |
| COL1A2 | collagen, type I, alpha 2 | -0.0473701 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0461269 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0436613 |
| PKM | pyruvate kinase, muscle | -0.0427849 |
| GOLGA4 | golgin A4 | -0.0420699 |
| MMP12 | matrix metallopeptidase 12 | -0.0418712 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0389628 |
| FAM20C | family with sequence similarity 20, member C | -0.038922 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0384911 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0384149 |
| ITGA1 | integrin, alpha 1 | -0.0370422 |
| POTEF | POTE ankyrin domain family, member F | -0.0360175 |
| MMP2 | matrix metallopeptidase 2 | -0.0359859 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0356373 |
| TMEM178B | transmembrane protein 178B | -0.0345428 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0340589 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0331221 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0324804 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0300928 |
| VEGFA | vascular endothelial growth factor A | -0.0295587 |
| RPS21 | ribosomal protein S21 | -0.0281409 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0273947 |
| FTL | ferritin, light polypeptide | -0.0266176 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0264737 |
| C1R | complement component 1, r subcomponent | -0.0264106 |
| S100A6 | S100 calcium binding protein A6 | -0.0258927 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0257503 |
| FBN1 | fibrillin 1 | -0.0256992 |
| AGRN | agrin | -0.0252161 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0250592 |
| SETD5 | SET domain containing 5 | -0.025059 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0250271 |
| COL5A2 | collagen, type V, alpha 2 | -0.0247952 |
| DSTN | destrin (actin depolymerizing factor) | -0.0247758 |
| KLF13 | Kruppel-like factor 13 | -0.0243846 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0240954 |
| TAOK1 | TAO kinase 1 | -0.024075 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0234639 |
| FAM162A | family with sequence similarity 162, member A | -0.0231666 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0226901 |
| DNHD1 | dynein heavy chain domain 1 | -0.0226841 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0225904 |
| WASF2 | WAS protein family, member 2 | -0.0225888 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0225492 |
| TTYH3 | tweety family member 3 | -0.0224872 |
| RPL23 | ribosomal protein L23 | -0.0224674 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0224666 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0222187 |
| GOLGA3 | golgin A3 | -0.0218768 |
| RPL34 | ribosomal protein L34 | -0.02187 |
| TUBB6 | tubulin, beta 6 class V | -0.0213936 |
| SERF2 | small EDRK-rich factor 2 | -0.0212739 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0210921 |
| AEBP1 | AE binding protein 1 | -0.0210595 |
| MSN | moesin | -0.0209064 |
| LOXL2 | lysyl oxidase-like 2 | -0.0208946 |
| EHD2 | EH-domain containing 2 | -0.0208211 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0208203 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0207386 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0207091 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | -0.0206221 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0204007 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0203178 |
| ASPH | aspartate beta-hydroxylase | -0.0202282 |
| RPS6 | ribosomal protein S6 | -0.0202142 |
| PFN1 | profilin 1 | -0.020175 |
| TWIST2 | twist family bHLH transcription factor 2 | -0.0200767 |
| RBPMS | RNA binding protein with multiple splicing | -0.0200059 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0199925 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0199156 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.01981 |
| VIRMA | vir like m6A methyltransferase associated | -0.019734 |
| PTGFR | prostaglandin F receptor (FP) | -0.0195557 |
| RRBP1 | ribosome binding protein 1 | -0.0194575 |
| GNAS | GNAS complex locus | -0.0193753 |
| SNX14 | sorting nexin 14 | -0.0193377 |
| ARF4 | ADP-ribosylation factor 4 | -0.019322 |
| ZNF292 | zinc finger protein 292 | -0.0191147 |
| SEC61G | Sec61 gamma subunit | -0.0190502 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0190462 |
| CDH13 | cadherin 13 | -0.018717 |
| RPLP1 | ribosomal protein, large, P1 | -0.0183926 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0183782 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.018185 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0181402 |
| RAI14 | retinoic acid induced 14 | -0.0180897 |
| RPL36 | ribosomal protein L36 | -0.0179108 |
| QRICH1 | glutamine-rich 1 | -0.0177616 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.017532 |
