| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Norepinephrine (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.111213 |
| TENM1 | teneurin transmembrane protein 1 | 0.0896659 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0750273 |
| MCL1 | myeloid cell leukemia 1 | 0.0733264 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0686019 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0660086 |
| INHBA | inhibin, beta A | 0.0658659 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0631581 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0609285 |
| ASPH | aspartate beta-hydroxylase | 0.057662 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0565737 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.055959 |
| PTMA | prothymosin, alpha | 0.0523762 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0521211 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0492362 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0469123 |
| PDE10A | phosphodiesterase 10A | 0.0461479 |
| NBEA | neurobeachin | 0.0456204 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0447741 |
| RNF213 | ring finger protein 213 | 0.0446416 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0445963 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0444959 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0444923 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0444215 |
| TXNRD1 | thioredoxin reductase 1 | 0.0440709 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0440219 |
| ACTG1 | actin gamma 1 | 0.0430198 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0425784 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0423586 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.041419 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.0414118 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0401203 |
| NAV2 | neuron navigator 2 | 0.0390593 |
| CHGA | chromogranin A | 0.038892 |
| NCKAP5 | NCK-associated protein 5 | 0.0388904 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0384416 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0379374 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0378884 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.036972 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0364501 |
| SCFD2 | sec1 family domain containing 2 | 0.0362333 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0356701 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0354006 |
| IRS2 | insulin receptor substrate 2 | 0.0353354 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0351812 |
| SIK2 | salt-inducible kinase 2 | 0.0342661 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0342168 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0340713 |
| ZFHX3 | zinc finger homeobox 3 | 0.0337457 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | 0.0331583 |
| EHBP1 | EH domain binding protein 1 | 0.0330319 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0327021 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0327012 |
| SMYD3 | SET and MYND domain containing 3 | 0.032015 |
| SETX | senataxin | 0.0317409 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0313153 |
| TPM4 | tropomyosin 4 | 0.0310388 |
| EGFR | epidermal growth factor receptor | 0.0309091 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0308651 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0303956 |
| PTCHD4 | patched domain containing 4 | 0.0298482 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0297932 |
| PALLD | palladin, cytoskeletal associated protein | 0.0294124 |
| FGF14 | fibroblast growth factor 14 | 0.0291747 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0289852 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0285247 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0285216 |
| EPHA4 | EPH receptor A4 | 0.0277284 |
| PUM3 | pumilio RNA binding family member 3 | 0.0275943 |
| MX2 | MX dynamin-like GTPase 2 | 0.0273831 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | 0.0272615 |
| VCL | vinculin | 0.0269825 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0266446 |
| INTS6 | integrator complex subunit 6 | 0.0260848 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0260435 |
| PCBP3 | poly(rC) binding protein 3 | 0.0260402 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0260159 |
| AOPEP | aminopeptidase O (putative) | 0.0260137 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0259237 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0259122 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0254734 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0251868 |
| SIK3 | SIK family kinase 3 | 0.0251622 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0249887 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.024741 |
| TUSC3 | tumor suppressor candidate 3 | 0.0246839 |
| ZMAT4 | zinc finger, matrin-type 4 | 0.0246465 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0245109 |
| TOX | thymocyte selection-associated high mobility group box | 0.0244489 |
| MYO9A | myosin IXA | 0.0243358 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0242757 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0242744 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0241738 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0240628 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0239848 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0239547 |
| TOP1 | topoisomerase (DNA) I | 0.0239302 |
| USP34 | ubiquitin specific peptidase 34 | 0.023835 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0237179 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0236 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.0860012 |
| VGF | VGF nerve growth factor inducible | -0.0858452 |
| RIT2 | Ras-like without CAAX 2 | -0.0599198 |
| PEG10 | paternally expressed 10 | -0.0523609 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0505981 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0475202 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0436443 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0423763 |
| ENO1 | enolase 1, (alpha) | -0.0402323 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0391608 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0382574 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0374275 |
| MAP1B | microtubule-associated protein 1B | -0.0365416 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0363108 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.0360193 |
| CENPF | centromere protein F, 350/400kDa | -0.0337695 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0335993 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0333869 |
| GPC6 | glypican 6 | -0.0312235 |
| PKM | pyruvate kinase, muscle | -0.0309181 |
| DTNA | dystrobrevin, alpha | -0.0303902 |
| RTN4 | reticulon 4 | -0.0302814 |
| RPL26 | ribosomal protein L26 | -0.0296568 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0295514 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0292704 |
| GSE1 | Gse1 coiled-coil protein | -0.029177 |
| CHGB | chromogranin B | -0.0291186 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0288051 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0285088 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0269594 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | -0.0262659 |
| VEGFA | vascular endothelial growth factor A | -0.026169 |
| PFN1 | profilin 1 | -0.0259009 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0257069 |
| NFIA | nuclear factor I/A | -0.0256234 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0254338 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0253867 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0245045 |
| ESRRG | estrogen-related receptor gamma | -0.0244716 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0240316 |
| SYT1 | synaptotagmin I | -0.0240118 |
| KLHL24 | kelch-like family member 24 | -0.0233345 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0232541 |
| BSG | basigin (Ok blood group) | -0.0232391 |
| NEMF | nuclear export mediator factor | -0.0227742 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0225422 |
| ZNF292 | zinc finger protein 292 | -0.0223977 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0223603 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.022208 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0220184 |
| NELL1 | NEL-like 1 (chicken) | -0.0219191 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0215265 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0213412 |
| TMSB4X | thymosin beta 4, X-linked | -0.021333 |
| NRG1 | neuregulin 1 | -0.0213265 |
| FOXO1 | forkhead box O1 | -0.0208958 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0208916 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0208682 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0208232 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.020396 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0200369 |
| S100A9 | S100 calcium binding protein A9 | -0.0199963 |
| RPS21 | ribosomal protein S21 | -0.019983 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0194714 |
| SCG2 | secretogranin II | -0.0193001 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0191219 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0188433 |
| PDE8A | phosphodiesterase 8A | -0.0188406 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.018798 |
| VWDE | von Willebrand factor D and EGF domains | -0.0187881 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.0187816 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0187028 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0184386 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0181879 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0180149 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.018006 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0179555 |
| TSHZ1 | teashirt zinc finger homeobox 1 | -0.0178991 |
| ECT2 | epithelial cell transforming 2 | -0.0178246 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0177218 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0177098 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.017676 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0175105 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.01747 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0174356 |
| NUP54 | nucleoporin 54kDa | -0.0174185 |
| ZNF148 | zinc finger protein 148 | -0.0173395 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0171893 |
| FOXC1 | forkhead box C1 | -0.0171591 |
| ZNF395 | zinc finger protein 395 | -0.0171279 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0171269 |
| NBAS | neuroblastoma amplified sequence | -0.0171104 |
| FNIP1 | folliculin interacting protein 1 | -0.0170917 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0170702 |
| KAT7 | K(lysine) acetyltransferase 7 | -0.0170336 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0168974 |
| HLA-A | major histocompatibility complex, class I, A | -0.0167909 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0166691 |
| ANLN | anillin, actin binding protein | -0.0166119 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0163773 |
