| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.105868 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0980396 |
| FMN1 | formin 1 | 0.0626191 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.057594 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0572049 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0514069 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0504054 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0483285 |
| CDK6 | cyclin-dependent kinase 6 | 0.0480667 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0474032 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0469816 |
| RUNX1 | runt-related transcription factor 1 | 0.0454363 |
| DST | dystonin | 0.0454142 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0445429 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0440943 |
| LDHA | lactate dehydrogenase A | 0.0418427 |
| ATXN1 | ataxin 1 | 0.0415179 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0399802 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0398579 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0394831 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0393671 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0393135 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0390749 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0378718 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0363226 |
| RNF213 | ring finger protein 213 | 0.0363048 |
| FMNL2 | formin-like 2 | 0.0360256 |
| SP100 | SP100 nuclear antigen | 0.0359875 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0359612 |
| NAV1 | neuron navigator 1 | 0.0358934 |
| PLAT | plasminogen activator, tissue | 0.0354575 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0352692 |
| CYTH3 | cytohesin 3 | 0.0352037 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0347046 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0342709 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0341931 |
| WWOX | WW domain containing oxidoreductase | 0.0334105 |
| CLIC4 | chloride intracellular channel 4 | 0.0331817 |
| HDAC9 | histone deacetylase 9 | 0.0331173 |
| PTK2 | protein tyrosine kinase 2 | 0.032884 |
| FLNB | filamin B, beta | 0.0328136 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0324379 |
| VCL | vinculin | 0.0323679 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0318462 |
| SMAD3 | SMAD family member 3 | 0.0317306 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0314202 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0311376 |
| ANLN | anillin, actin binding protein | 0.0309629 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0309477 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0305934 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0305886 |
| CENPF | centromere protein F, 350/400kDa | 0.0303238 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0303095 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0298409 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0296094 |
| MACROD2 | MACRO domain containing 2 | 0.0294092 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.029313 |
| CTTN | cortactin | 0.028974 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0289026 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.028802 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0280894 |
| ZNF608 | zinc finger protein 608 | 0.0277287 |
| ERBIN | erbb2 interacting protein | 0.0275367 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0275352 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0275095 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0272732 |
| IFI44L | interferon-induced protein 44-like | 0.027206 |
| FGGY | FGGY carbohydrate kinase domain containing | 0.0266386 |
| CTBP2 | C-terminal binding protein 2 | 0.0264026 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0263287 |
| ETV6 | ets variant 6 | 0.0259796 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0258106 |
| RIGI | RNA sensor RIG-I | 0.0257661 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.025545 |
| FRMD5 | FERM domain containing 5 | 0.0253446 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0252967 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0251429 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0247719 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0245403 |
| RANGAP1 | Ran GTPase activating protein 1 | 0.0245097 |
| COG5 | component of oligomeric golgi complex 5 | 0.0244534 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0243239 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | 0.02427 |
| EFNA5 | ephrin-A5 | 0.0241871 |
| ACTN1 | actinin, alpha 1 | 0.023961 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.023908 |
| RPS3 | ribosomal protein S3 | 0.0238495 |
| AMOTL1 | angiomotin like 1 | 0.0237897 |
| BPTF | bromodomain PHD finger transcription factor | 0.02371 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0236863 |
| TJP1 | tight junction protein 1 | 0.0236554 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0236231 |
| PMP22 | peripheral myelin protein 22 | 0.0235349 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0232806 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0232242 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0231514 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0229667 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0226872 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0226852 |
| B2M | beta-2-microglobulin | 0.0222528 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.225119 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181291 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.157173 |
| MT2A | metallothionein 2A | -0.0899023 |
| LSAMP | limbic system-associated membrane protein | -0.0879641 |
| GOLGA4 | golgin A4 | -0.0764825 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0596918 |
| PKM | pyruvate kinase, muscle | -0.0561633 |
| RPLP1 | ribosomal protein, large, P1 | -0.0545253 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0507081 |
| PMEL | premelanosome protein | -0.0480085 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0473331 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0458794 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0447245 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0423447 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0419176 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0409797 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0399629 |
| RPL34 | ribosomal protein L34 | -0.0396832 |
| SQSTM1 | sequestosome 1 | -0.03937 |
| TMSB10 | thymosin beta 10 | -0.0382751 |
| TXNRD1 | thioredoxin reductase 1 | -0.0368952 |
| NRG3 | neuregulin 3 | -0.0356094 |
| MATR3 | matrin 3 | -0.0348896 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0328652 |
| RPL12 | ribosomal protein L12 | -0.0322873 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0315987 |
| RAB7A | RAB7A, member RAS oncogene family | -0.030719 |
| CLINT1 | clathrin interactor 1 | -0.0304137 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0295643 |
| FTL | ferritin, light polypeptide | -0.0289282 |
| CADM1 | cell adhesion molecule 1 | -0.0282253 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0274547 |
| RPS23 | ribosomal protein S23 | -0.0273738 |
| RPL32 | ribosomal protein L32 | -0.0269542 |
| RPS6 | ribosomal protein S6 | -0.0268408 |
| RPL23 | ribosomal protein L23 | -0.0265866 |
| PHF3 | PHD finger protein 3 | -0.0264562 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0264435 |
| MMP12 | matrix metallopeptidase 12 | -0.0260792 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0257708 |
| RPL36 | ribosomal protein L36 | -0.0248503 |
| FILIP1 | filamin A interacting protein 1 | -0.0247883 |
| KAZN | kazrin, periplakin interacting protein | -0.0247622 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0247129 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0246157 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0244529 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0242756 |
| RPL35A | ribosomal protein L35a | -0.024202 |
| ZNF654 | zinc finger protein 654 | -0.0237725 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0234821 |
| PRAME | preferentially expressed antigen in melanoma | -0.0233544 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0232021 |
| RLIM | ring finger protein, LIM domain interacting | -0.0231607 |
| JMJD1C | jumonji domain containing 1C | -0.0223574 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0220691 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0216676 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0216611 |
| VIM | vimentin | -0.0216368 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0212132 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.02107 |
| RPL36A | ribosomal protein L36a | -0.020907 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0208676 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0207747 |
| RPS14 | ribosomal protein S14 | -0.0207068 |
| NGLY1 | N-glycanase 1 | -0.0204137 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0202873 |
| RPS29 | ribosomal protein S29 | -0.0201234 |
| MT1X | metallothionein 1X | -0.0199652 |
| MAP4 | microtubule-associated protein 4 | -0.0199172 |
| RPL35 | ribosomal protein L35 | -0.0198164 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0197269 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0191376 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0191318 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0189105 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0186994 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0185125 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.018471 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0183574 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0182263 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0182184 |
| CLEC2D | C-type lectin domain family 2, member D | -0.0180827 |
| RPS20 | ribosomal protein S20 | -0.0180496 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0177295 |
| FAM219A | family with sequence similarity 219, member A | -0.0177269 |
| NBPF8 | neuroblastoma breakpoint family, member 8 | -0.0177213 |
| DIAPH2 | diaphanous-related formin 2 | -0.0175139 |
| TUBB | tubulin, beta class I | -0.0174896 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0174403 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0172898 |
| ZNF121 | zinc finger protein 121 | -0.0172522 |
| RPL14 | ribosomal protein L14 | -0.0171717 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0171697 |
| RPS21 | ribosomal protein S21 | -0.0170977 |
| A2M | alpha-2-macroglobulin | -0.0170863 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.01689 |
| RPS27 | ribosomal protein S27 | -0.0166128 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0166023 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | -0.0166016 |
| ZNF292 | zinc finger protein 292 | -0.0165566 |
