| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.157682 |
| TJP1 | tight junction protein 1 | 0.147936 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0963001 |
| HDAC9 | histone deacetylase 9 | 0.0940289 |
| PKM | pyruvate kinase, muscle | 0.0886495 |
| PDGFC | platelet derived growth factor C | 0.0786904 |
| AHNAK | AHNAK nucleoprotein | 0.0755589 |
| ZNF608 | zinc finger protein 608 | 0.0703937 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0606558 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.058527 |
| PRELID2 | PRELI domain containing 2 | 0.0570428 |
| PCBP2 | poly(rC) binding protein 2 | 0.0561535 |
| GLI2 | GLI family zinc finger 2 | 0.0542186 |
| MYO5C | myosin VC | 0.053565 |
| LDHA | lactate dehydrogenase A | 0.0527505 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0518146 |
| DIAPH3 | diaphanous-related formin 3 | 0.0490588 |
| MACROD2 | MACRO domain containing 2 | 0.0488744 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0486791 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0476246 |
| GLI3 | GLI family zinc finger 3 | 0.0466973 |
| ANLN | anillin, actin binding protein | 0.0449699 |
| PFN1 | profilin 1 | 0.0416226 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0401961 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0401714 |
| IRS1 | insulin receptor substrate 1 | 0.0394802 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0392212 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0380368 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0378178 |
| DUSP4 | dual specificity phosphatase 4 | 0.0366463 |
| TXNRD1 | thioredoxin reductase 1 | 0.0360704 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0355383 |
| TPI1 | triosephosphate isomerase 1 | 0.0354286 |
| VCL | vinculin | 0.03526 |
| FAT1 | FAT atypical cadherin 1 | 0.0348224 |
| BMP2K | BMP2 inducible kinase | 0.0346662 |
| ECT2 | epithelial cell transforming 2 | 0.0344436 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0335441 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0334119 |
| FER1L6 | fer-1-like family member 6 | 0.0330562 |
| ATP9B | ATPase, class II, type 9B | 0.0324903 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0323087 |
| MT2A | metallothionein 2A | 0.0321963 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0319639 |
| EZR | ezrin | 0.0317909 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0316901 |
| TMEM65 | transmembrane protein 65 | 0.0313984 |
| GSE1 | Gse1 coiled-coil protein | 0.03132 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0309864 |
| CCDC68 | coiled-coil domain containing 68 | 0.0306756 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0302386 |
| RRM2 | ribonucleotide reductase M2 | 0.0300078 |
| SFTPA2 | surfactant protein A2 | 0.0299858 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0299502 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0295742 |
| PYGB | phosphorylase, glycogen; brain | 0.0295045 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0291193 |
| SQSTM1 | sequestosome 1 | 0.0291133 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0290052 |
| RPL12 | ribosomal protein L12 | 0.0289065 |
| RACK1 | receptor for activated C kinase 1 | 0.0288877 |
| S100A4 | S100 calcium binding protein A4 | 0.028756 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0287274 |
| RPS8 | ribosomal protein S8 | 0.0286966 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0284784 |
| YAP1 | Yes-associated protein 1 | 0.0283363 |
| RHOA | ras homolog family member A | 0.0282613 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0280197 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0278637 |
| PTMS | parathymosin | 0.0278396 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0275703 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 0.0273497 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0271327 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0269887 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.026983 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0267649 |
| TRIM24 | tripartite motif containing 24 | 0.0265822 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0264622 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0263021 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0260685 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0257895 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0255349 |
| EEA1 | early endosome antigen 1 | 0.0253832 |
| SCFD1 | sec1 family domain containing 1 | 0.0251366 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0248861 |
| LOXL3 | lysyl oxidase-like 3 | 0.0248181 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0247137 |
| ENO1 | enolase 1, (alpha) | 0.024609 |
| SNX14 | sorting nexin 14 | 0.0243837 |
| SET | SET nuclear proto-oncogene | 0.0241284 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0240121 |
| B2M | beta-2-microglobulin | 0.0239341 |
| ZNF217 | zinc finger protein 217 | 0.0237779 |
| TRIOBP | TRIO and F-actin binding protein | 0.0235411 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0234415 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0233481 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0233405 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0231976 |
| NCKAP1 | NCK-associated protein 1 | 0.0231748 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0231631 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.170999 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121378 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114518 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.11147 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.10132 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0991836 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0611018 |
| FOXP1 | forkhead box P1 | -0.05484 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0524129 |
| RPS23 | ribosomal protein S23 | -0.0522627 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0511255 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0487752 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0478351 |
| SBF2 | SET binding factor 2 | -0.0467884 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0446564 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0439986 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0438136 |
| RHBDD1 | rhomboid domain containing 1 | -0.0428736 |
| RPS25 | ribosomal protein S25 | -0.0414535 |
| HDLBP | high density lipoprotein binding protein | -0.0399514 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0396233 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0393061 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390526 |
| RLF | rearranged L-myc fusion | -0.0386813 |
| RPS29 | ribosomal protein S29 | -0.0385046 |
| RPL13A | ribosomal protein L13a | -0.0378298 |
| RRBP1 | ribosome binding protein 1 | -0.0369778 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0357857 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0356643 |
| COG5 | component of oligomeric golgi complex 5 | -0.0354324 |
| RPS13 | ribosomal protein S13 | -0.035263 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0349522 |
| EXOC6B | exocyst complex component 6B | -0.0348285 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0348116 |
| NEBL | nebulette | -0.034282 |
| RPL38 | ribosomal protein L38 | -0.0342565 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0340993 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0338946 |
| SRPK2 | SRSF protein kinase 2 | -0.0337631 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0331635 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0330748 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0330595 |
| TCF12 | transcription factor 12 | -0.0327245 |
| HLA-B | major histocompatibility complex, class I, B | -0.0325198 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0322543 |
| PHF14 | PHD finger protein 14 | -0.0320569 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0319945 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0316239 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0315566 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.031464 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0311719 |
| NFIA | nuclear factor I/A | -0.0309246 |
| JMJD1C | jumonji domain containing 1C | -0.0305004 |
| RPS3 | ribosomal protein S3 | -0.0303873 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.030239 |
| RPL34 | ribosomal protein L34 | -0.0302193 |
| CALR | calreticulin | -0.0300371 |
| HMGB1 | high mobility group box 1 | -0.0299718 |
| RBM39 | RNA binding motif protein 39 | -0.0298157 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.029736 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0297218 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0292058 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0291108 |
| DENND1A | DENN/MADD domain containing 1A | -0.0288927 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0288027 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0286052 |
| LIMD1 | LIM domains containing 1 | -0.0283405 |
| PGK1 | phosphoglycerate kinase 1 | -0.0281115 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0276498 |
| TMEM41B | transmembrane protein 41B | -0.0275922 |
| OSMR | oncostatin M receptor | -0.0273836 |
| NOP56 | NOP56 ribonucleoprotein | -0.0272298 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0271778 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0269266 |
| NBEA | neurobeachin | -0.0268356 |
| CBFB | core-binding factor, beta subunit | -0.0266854 |
| RBM8A | RNA binding motif protein 8A | -0.0266543 |
| RPS24 | ribosomal protein S24 | -0.0264552 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0263071 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0261858 |
| ELP2 | elongator acetyltransferase complex subunit 2 | -0.0260681 |
| ZNF292 | zinc finger protein 292 | -0.0259292 |
| RPL35A | ribosomal protein L35a | -0.0258254 |
| ZNF609 | zinc finger protein 609 | -0.0258243 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0257402 |
| RPS6 | ribosomal protein S6 | -0.0254596 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0253301 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0250768 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0250548 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0248466 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0248208 |
| SAFB2 | scaffold attachment factor B2 | -0.0247779 |
| RPS15A | ribosomal protein S15a | -0.02454 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0245342 |
| NGLY1 | N-glycanase 1 | -0.0244018 |
| RPS15 | ribosomal protein S15 | -0.0243421 |
| PWWP2A | PWWP domain containing 2A | -0.0242022 |
| MSI2 | musashi RNA-binding protein 2 | -0.0240622 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0240098 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0238884 |