| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Norepinephrine (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IER3 | immediate early response 3 | 0.0504701 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0476829 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0455273 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0431528 |
| HDAC9 | histone deacetylase 9 | 0.0409755 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0408224 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.038559 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0370251 |
| MT2A | metallothionein 2A | 0.0352254 |
| SQSTM1 | sequestosome 1 | 0.0346971 |
| ASPH | aspartate beta-hydroxylase | 0.0345981 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0305017 |
| WWOX | WW domain containing oxidoreductase | 0.0288088 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0271017 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0268768 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0260301 |
| RPL4 | ribosomal protein L4 | 0.0255098 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0254552 |
| ANXA2 | annexin A2 | 0.0252059 |
| ACTG1 | actin gamma 1 | 0.0238169 |
| SYNJ2 | synaptojanin 2 | 0.0233492 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0226492 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0225111 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0221698 |
| INTS6 | integrator complex subunit 6 | 0.0216998 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0216277 |
| LDHA | lactate dehydrogenase A | 0.0210431 |
| RPS24 | ribosomal protein S24 | 0.0203435 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0203208 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0202578 |
| MLPH | melanophilin | 0.0199587 |
| HLA-E | major histocompatibility complex, class I, E | 0.0197116 |
| RPL37A | ribosomal protein L37a | 0.0192606 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0188864 |
| NAV2 | neuron navigator 2 | 0.0188462 |
| VCL | vinculin | 0.0186262 |
| SVIL | supervillin | 0.018479 |
| GPC6 | glypican 6 | 0.0182679 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0182495 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0182203 |
| CRY1 | cryptochrome circadian clock 1 | 0.0181727 |
| AHNAK | AHNAK nucleoprotein | 0.0178795 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0177607 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0177143 |
| SMAD3 | SMAD family member 3 | 0.0171144 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0170674 |
| DUSP10 | dual specificity phosphatase 10 | 0.0166221 |
| APP | amyloid beta (A4) precursor protein | 0.0164313 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0163692 |
| IPO7 | importin 7 | 0.0162363 |
| ANXA1 | annexin A1 | 0.0162076 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0161162 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0159081 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0159018 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0157064 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0156998 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0152705 |
| RPLP0 | ribosomal protein, large, P0 | 0.0152074 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0150093 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0148151 |
| FHIT | fragile histidine triad | 0.0147642 |
| WTAP | Wilms tumor 1 associated protein | 0.0146898 |
| IRS2 | insulin receptor substrate 2 | 0.014653 |
| MYO10 | myosin X | 0.0146456 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0145329 |
| EFNA5 | ephrin-A5 | 0.0145294 |
| RPL7 | ribosomal protein L7 | 0.0136082 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0135655 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0135537 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0134383 |
| XPO1 | exportin 1 | 0.0134339 |
| RYBP | RING1 and YY1 binding protein | 0.0133894 |
| COL5A1 | collagen, type V, alpha 1 | 0.013376 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0133445 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0130898 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0130098 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0129016 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0127646 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.012694 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.012679 |
| STX3 | syntaxin 3 | 0.0126647 |
| RUNX1 | runt-related transcription factor 1 | 0.0126096 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.012603 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0125915 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0125366 |
| CCND1 | cyclin D1 | 0.0124762 |
| PRELID2 | PRELI domain containing 2 | 0.0124581 |
| STC1 | stanniocalcin 1 | 0.0123472 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0123046 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0122458 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0121168 |
| FAM107B | family with sequence similarity 107, member B | 0.0120451 |
| IRF1 | interferon regulatory factor 1 | 0.0120402 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0119614 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0119255 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0118385 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0117788 |
| SSR1 | signal sequence receptor, alpha | 0.0117617 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0116347 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0115533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.19 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.153404 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.138187 |
| VIM | vimentin | -0.10674 |
| VEGFA | vascular endothelial growth factor A | -0.101422 |
| FN1 | fibronectin 1 | -0.0848623 |
| CADM1 | cell adhesion molecule 1 | -0.0781679 |
| VCAN | versican | -0.0765662 |
| CD44 | CD44 molecule (Indian blood group) | -0.0674872 |
| FRMD4A | FERM domain containing 4A | -0.0669618 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0666135 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0639829 |
| NDRG1 | N-myc downstream regulated 1 | -0.0629359 |
| PDE10A | phosphodiesterase 10A | -0.0622821 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0586338 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0568696 |
| GLIS3 | GLIS family zinc finger 3 | -0.0534922 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0532245 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0518617 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0509594 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0501832 |
| RAI14 | retinoic acid induced 14 | -0.0475802 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0457847 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0454792 |
| EGR1 | early growth response 1 | -0.0441074 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0439321 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.043593 |
| FLNB | filamin B, beta | -0.0431903 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0423306 |
| HLA-A | major histocompatibility complex, class I, A | -0.0415529 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0406034 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0402942 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0402426 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0398761 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0396193 |
| LOX | lysyl oxidase | -0.0394085 |
| MSN | moesin | -0.0392432 |
| DIAPH2 | diaphanous-related formin 2 | -0.0392336 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0387503 |
| GOLGA4 | golgin A4 | -0.0381934 |
| DST | dystonin | -0.0369249 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0367722 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0367137 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0361062 |
| TMSB10 | thymosin beta 10 | -0.0358873 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.034449 |
| CLMP | CXADR-like membrane protein | -0.0343172 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0342347 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0334412 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0331112 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0315489 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.03145 |
| PCBP2 | poly(rC) binding protein 2 | -0.0313825 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0312681 |
| SBF2 | SET binding factor 2 | -0.0309748 |
| PLIN2 | perilipin 2 | -0.0309411 |
| C3 | complement component 3 | -0.0306023 |
| ATP13A3 | ATPase type 13A3 | -0.0300704 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.02985 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.029706 |
| STC2 | stanniocalcin 2 | -0.0293764 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0293275 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0290843 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0289066 |
| MAP4 | microtubule-associated protein 4 | -0.0284124 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0283651 |
| WASF2 | WAS protein family, member 2 | -0.0274724 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0272707 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0268279 |
| RTN4 | reticulon 4 | -0.0267168 |
| PRRC2C | proline-rich coiled-coil 2C | -0.026653 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0262172 |
| PHF21A | PHD finger protein 21A | -0.0260545 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0260322 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0258919 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0257929 |
| IL6 | interleukin 6 | -0.0252959 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0251791 |
| MMP12 | matrix metallopeptidase 12 | -0.0249968 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0248417 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0246321 |
| LRRC7 | leucine rich repeat containing 7 | -0.0245015 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.024293 |
| NGLY1 | N-glycanase 1 | -0.0240152 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0237727 |
| TAPBP | TAP binding protein (tapasin) | -0.0236383 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0235092 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0233627 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0232976 |
| COL1A2 | collagen, type I, alpha 2 | -0.0231288 |
| CDCP1 | CUB domain containing protein 1 | -0.0231028 |
| VMP1 | vacuole membrane protein 1 | -0.0227881 |
| EGFR | epidermal growth factor receptor | -0.0226165 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0225316 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.022381 |
| MATR3 | matrin 3 | -0.022335 |
| THOC2 | THO complex 2 | -0.0222729 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0222025 |
| OSMR | oncostatin M receptor | -0.0219251 |
| CFB | complement factor B | -0.0218605 |
