| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Norepinephrine (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RCOR1 | REST corepressor 1 | 0.135337 |
| EGFR | epidermal growth factor receptor | 0.132751 |
| ACTG1 | actin gamma 1 | 0.122966 |
| LAMA4 | laminin, alpha 4 | 0.0877377 |
| SMAD3 | SMAD family member 3 | 0.0773024 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0767816 |
| SEPTIN9 | septin 9 | 0.0761061 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.069015 |
| HMGA2 | high mobility group AT-hook 2 | 0.0663177 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0652949 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0639291 |
| FHIT | fragile histidine triad | 0.0546651 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0545717 |
| VCL | vinculin | 0.0521839 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0482759 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0478179 |
| ABR | active BCR-related | 0.0473675 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0469579 |
| EFNB2 | ephrin-B2 | 0.0464266 |
| GPHN | gephyrin | 0.0462716 |
| LAMC2 | laminin, gamma 2 | 0.0459171 |
| SGMS2 | sphingomyelin synthase 2 | 0.0447544 |
| EMP1 | epithelial membrane protein 1 | 0.0441298 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0439154 |
| CMIP | c-Maf inducing protein | 0.0429561 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0426292 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0405381 |
| RAD51B | RAD51 paralog B | 0.0401829 |
| ATL2 | atlastin GTPase 2 | 0.0383768 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0380928 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0374058 |
| ANKRD17 | ankyrin repeat domain 17 | 0.036969 |
| CUX1 | cut-like homeobox 1 | 0.0367327 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.036553 |
| SLC30A10 | solute carrier family 30, member 10 | 0.0361763 |
| NUP50 | nucleoporin 50kDa | 0.0357556 |
| PHF14 | PHD finger protein 14 | 0.0355365 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0355249 |
| SMYD3 | SET and MYND domain containing 3 | 0.0348119 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0343297 |
| TNS3 | tensin 3 | 0.0330255 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0326825 |
| AREG | amphiregulin | 0.0324013 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0323107 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0320144 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.031909 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0311443 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0310117 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0307542 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0305007 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0299169 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0292984 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0291281 |
| ATXN1 | ataxin 1 | 0.0291192 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0289383 |
| HOMER1 | homer scaffolding protein 1 | 0.0286313 |
| ANXA2 | annexin A2 | 0.0284959 |
| WWOX | WW domain containing oxidoreductase | 0.0284392 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0280833 |
| WWC1 | WW and C2 domain containing 1 | 0.0280709 |
| IER3 | immediate early response 3 | 0.0276939 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.027409 |
| RRM2 | ribonucleotide reductase M2 | 0.0272961 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0272621 |
| PARD3B | par-3 family cell polarity regulator beta | 0.027159 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.02712 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0265426 |
| TRAF3 | TNF receptor-associated factor 3 | 0.0264908 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0261342 |
| EXOC4 | exocyst complex component 4 | 0.0259933 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0259445 |
| FHL2 | four and a half LIM domains 2 | 0.0257233 |
| DSPP | dentin sialophosphoprotein | 0.0257098 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0256763 |
| TENM3 | teneurin transmembrane protein 3 | 0.0253677 |
| VMP1 | vacuole membrane protein 1 | 0.0250277 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0249255 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0248628 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0243211 |
| MTAP | methylthioadenosine phosphorylase | 0.023788 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0237838 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0236392 |
| JMJD1C | jumonji domain containing 1C | 0.0235755 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0235234 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0233029 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0232006 |
| CD9 | CD9 molecule | 0.0230526 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0229247 |
| RAB10 | RAB10, member RAS oncogene family | 0.0228735 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0227092 |
| CPOX | coproporphyrinogen oxidase | 0.0227034 |
| KSR2 | kinase suppressor of ras 2 | 0.0226773 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0223165 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0223107 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0221176 |
| KLF12 | Kruppel-like factor 12 | 0.0220607 |
| DST | dystonin | 0.0220538 |
| SIK3 | SIK family kinase 3 | 0.0218228 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0218074 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0214971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.12146 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.121135 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0881919 |
| GOLGA4 | golgin A4 | -0.0876481 |
| RPS6 | ribosomal protein S6 | -0.0834149 |
| RUNX2 | runt-related transcription factor 2 | -0.0678258 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0649665 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0642234 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0554618 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.053461 |
| TXNRD1 | thioredoxin reductase 1 | -0.0507452 |
| RNF43 | ring finger protein 43 | -0.0496047 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0491783 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0455539 |
| LMO7 | LIM domain 7 | -0.0453933 |
| TOP1 | topoisomerase (DNA) I | -0.0448551 |
| MKI67 | marker of proliferation Ki-67 | -0.0416189 |
| RPL35A | ribosomal protein L35a | -0.0407324 |
| PKM | pyruvate kinase, muscle | -0.038639 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0381911 |
| EREG | epiregulin | -0.0380811 |
| FLOT1 | flotillin 1 | -0.0376455 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0367166 |
| RPL34 | ribosomal protein L34 | -0.0341172 |
| COG5 | component of oligomeric golgi complex 5 | -0.0334623 |
| RPLP1 | ribosomal protein, large, P1 | -0.033423 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0333306 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.033282 |
| USP3 | ubiquitin specific peptidase 3 | -0.0331939 |
| ZNF292 | zinc finger protein 292 | -0.0331139 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0316517 |
| RPL23 | ribosomal protein L23 | -0.0315178 |
| RPLP2 | ribosomal protein, large, P2 | -0.0304725 |
| NBAS | neuroblastoma amplified sequence | -0.0303739 |
| MT2A | metallothionein 2A | -0.0299542 |
| RPS27 | ribosomal protein S27 | -0.0296584 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0296099 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0291587 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0280822 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0277944 |
| EDAR | ectodysplasin A receptor | -0.0274345 |
| MATR3 | matrin 3 | -0.0271512 |
| NDRG1 | N-myc downstream regulated 1 | -0.0266658 |
| RPS19 | ribosomal protein S19 | -0.0263586 |
| OXR1 | oxidation resistance 1 | -0.02628 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0262301 |
| RPL32 | ribosomal protein L32 | -0.0261368 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0261157 |
| HMGA1 | high mobility group AT-hook 1 | -0.0260274 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0259056 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0255529 |
| LOC112694756 | uncharaterized LOC112694756 | -0.025315 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0252735 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0252591 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0245896 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.023909 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0237248 |
| GLG1 | golgi glycoprotein 1 | -0.023677 |
| RPS16 | ribosomal protein S16 | -0.0236764 |
| PTMA | prothymosin, alpha | -0.0236422 |
| TMSB10 | thymosin beta 10 | -0.0234234 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0230909 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0230842 |
| PHIP | pleckstrin homology domain interacting protein | -0.0230379 |
| RPL28 | ribosomal protein L28 | -0.0229113 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0228939 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0217498 |
| RPL35 | ribosomal protein L35 | -0.0216891 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0214559 |
| NUP58 | nucleoporin 58 | -0.0214109 |
| GDF15 | growth differentiation factor 15 | -0.02133 |
| RPS14 | ribosomal protein S14 | -0.0212552 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0210658 |
| FERMT1 | fermitin family member 1 | -0.0210603 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0209372 |
| RPS2 | ribosomal protein S2 | -0.020919 |
| RPS21 | ribosomal protein S21 | -0.0206957 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | -0.0206837 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0206537 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.020602 |
| NEK7 | NIMA-related kinase 7 | -0.0205833 |
| YBX1 | Y box binding protein 1 | -0.0205777 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0205166 |
| RPS25 | ribosomal protein S25 | -0.0204503 |
| RNF145 | ring finger protein 145 | -0.0204004 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0199537 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.019686 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0193015 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0192068 |
| AXIN2 | axin 2 | -0.0191625 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0191253 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0191243 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0191094 |
| RPS15 | ribosomal protein S15 | -0.0190269 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0189008 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0187907 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0187361 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0185588 |
| RPS5 | ribosomal protein S5 | -0.0180973 |
| CEP152 | centrosomal protein 152kDa | -0.0178661 |
