| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Norepinephrine (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Norepinephrine (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.137329 |
| EXT1 | exostosin glycosyltransferase 1 | 0.112525 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.109268 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.102707 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0950887 |
| VCL | vinculin | 0.095056 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0908168 |
| ASPH | aspartate beta-hydroxylase | 0.0749064 |
| GLIS3 | GLIS family zinc finger 3 | 0.0739009 |
| SMAD3 | SMAD family member 3 | 0.0717848 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0671212 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0652276 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0641291 |
| FN1 | fibronectin 1 | 0.0601836 |
| AHNAK | AHNAK nucleoprotein | 0.0583938 |
| INTS6 | integrator complex subunit 6 | 0.0531768 |
| MYO10 | myosin X | 0.0528705 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0501857 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0500003 |
| LOX | lysyl oxidase | 0.0499396 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0488146 |
| FRMD4A | FERM domain containing 4A | 0.0479725 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.047528 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0466891 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0446862 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0437819 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0435893 |
| CD44 | CD44 molecule (Indian blood group) | 0.0432819 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0425968 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0418721 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.041533 |
| LDHA | lactate dehydrogenase A | 0.0397242 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.038972 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.03874 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0360814 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345771 |
| COL5A3 | collagen, type V, alpha 3 | 0.0342868 |
| CALD1 | caldesmon 1 | 0.033356 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0332382 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0327367 |
| NAV1 | neuron navigator 1 | 0.0320538 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0320055 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0318208 |
| EGFR | epidermal growth factor receptor | 0.0310582 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0305616 |
| JAK1 | Janus kinase 1 | 0.0298211 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0288894 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0284342 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0284279 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0282048 |
| MED13L | mediator complex subunit 13-like | 0.0275148 |
| AMOTL1 | angiomotin like 1 | 0.0274331 |
| PDE8A | phosphodiesterase 8A | 0.0270781 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0268998 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0268836 |
| RAB31 | RAB31, member RAS oncogene family | 0.0267946 |
| RAD51B | RAD51 paralog B | 0.0259681 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0258378 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0251488 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0250292 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0246728 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0243366 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0242136 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0241748 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0239956 |
| EXOC4 | exocyst complex component 4 | 0.0239206 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0238482 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0235004 |
| NABP1 | nucleic acid binding protein 1 | 0.023366 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0233464 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0233369 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0233044 |
| COL5A1 | collagen, type V, alpha 1 | 0.02298 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0229779 |
| CLIC4 | chloride intracellular channel 4 | 0.022933 |
| ACTN1 | actinin, alpha 1 | 0.0228347 |
| ANXA2 | annexin A2 | 0.0227821 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0227192 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0224009 |
| IPO9 | importin 9 | 0.0223684 |
| NOTCH2 | notch 2 | 0.0223681 |
| PTK2 | protein tyrosine kinase 2 | 0.0222826 |
| JAG1 | jagged 1 | 0.0222801 |
| RCOR1 | REST corepressor 1 | 0.0222458 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0221767 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0221507 |
| RUNX1 | runt-related transcription factor 1 | 0.0220384 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0219166 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0218858 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0218581 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0217153 |
| RASAL2 | RAS protein activator like 2 | 0.0216768 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0216108 |
| RSU1 | Ras suppressor protein 1 | 0.0215617 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0213916 |
| CAVIN1 | caveolae associated protein 1 | 0.0212815 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0212671 |
| YAP1 | Yes-associated protein 1 | 0.0210552 |
| DGKI | diacylglycerol kinase, iota | 0.0210496 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0209398 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.197258 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0835509 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0764062 |
| STC1 | stanniocalcin 1 | -0.0747854 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0732004 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0721848 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.05942 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0584933 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0559993 |
| HLA-B | major histocompatibility complex, class I, B | -0.0536125 |
| MMP12 | matrix metallopeptidase 12 | -0.0534317 |
| FAM13A | family with sequence similarity 13, member A | -0.0523875 |
| COL6A1 | collagen, type VI, alpha 1 | -0.049981 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0494908 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0478552 |
| NDRG1 | N-myc downstream regulated 1 | -0.04753 |
| B2M | beta-2-microglobulin | -0.0433502 |
| TMEM165 | transmembrane protein 165 | -0.0426524 |
| RPS6 | ribosomal protein S6 | -0.0415982 |
| GOLGA4 | golgin A4 | -0.0399554 |
| COL1A2 | collagen, type I, alpha 2 | -0.0396675 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0396442 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.03908 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0366287 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0354483 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0349146 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0349046 |
| COL1A1 | collagen, type I, alpha 1 | -0.0342411 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0333338 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0324416 |
| INHBA | inhibin, beta A | -0.0309644 |
| TPM4 | tropomyosin 4 | -0.0308017 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0301012 |
| SNX9 | sorting nexin 9 | -0.0280445 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0270319 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.025561 |
| INSIG1 | insulin induced gene 1 | -0.0254704 |
| ZNF292 | zinc finger protein 292 | -0.0250735 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0250589 |
| ATP13A3 | ATPase type 13A3 | -0.0245116 |
| PTMA | prothymosin, alpha | -0.0244528 |
| NPTX1 | neuronal pentraxin I | -0.0233201 |
| PKM | pyruvate kinase, muscle | -0.0232875 |
| MMP1 | matrix metallopeptidase 1 | -0.0230503 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.022719 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0226463 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0217275 |
| VCAN | versican | -0.0209425 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0205242 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0203699 |
| RND3 | Rho family GTPase 3 | -0.0194993 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0194954 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0193361 |
| NGLY1 | N-glycanase 1 | -0.0192595 |
| NKTR | natural killer cell triggering receptor | -0.0191266 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0189371 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0188593 |
| NCKAP5 | NCK-associated protein 5 | -0.0184285 |
| WDR45B | WD repeat domain 45B | -0.0183151 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0182926 |
| MYADM | myeloid-associated differentiation marker | -0.0181656 |
| TMSB10 | thymosin beta 10 | -0.0181385 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0180423 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0180353 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0179914 |
| HLA-A | major histocompatibility complex, class I, A | -0.0179039 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0178052 |
| MEIS1 | Meis homeobox 1 | -0.0177977 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.017646 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0175402 |
| UBXN4 | UBX domain protein 4 | -0.0175239 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0174126 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0168018 |
| MAP1B | microtubule-associated protein 1B | -0.0167218 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0165837 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0165549 |
| IGF2 | insulin-like growth factor 2 | -0.0164672 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0159674 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0158704 |
| OXR1 | oxidation resistance 1 | -0.0158086 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0155406 |
| FOSL1 | FOS-like antigen 1 | -0.0155104 |
| STC2 | stanniocalcin 2 | -0.0154104 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.015218 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0150115 |
| PRRX1 | paired related homeobox 1 | -0.0148344 |
| ENO1 | enolase 1, (alpha) | -0.0147907 |
| ADM | adrenomedullin | -0.0147824 |
| ARRDC3 | arrestin domain containing 3 | -0.0146056 |
| E2F7 | E2F transcription factor 7 | -0.0145331 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0144862 |
| SERF2 | small EDRK-rich factor 2 | -0.0143983 |
| TMF1 | TATA element modulatory factor 1 | -0.014356 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0142599 |
| HAS2 | hyaluronan synthase 2 | -0.0141898 |
| MTSS1 | metastasis suppressor 1 | -0.0141792 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0141791 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0138209 |
| WASF2 | WAS protein family, member 2 | -0.0137985 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0136863 |
