Norfloxacin Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase. (Chemical Entities of Biological Interest Ontology, CHEBI_100246)
External Link http://www.hmdb.ca/metabolites/HMDB15192
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Genes

9 interacting proteins for the Norfloxacin metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
TOP2A topoisomerase (DNA) II alpha 170kDa