Notch Signaling Pathway(Homo sapiens) Gene Set

Dataset WikiPathways Pathways 2014
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP61_r78592
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Genes

80 proteins participating in the Notch Signaling Pathway(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AKT1 v-akt murine thymoma viral oncogene homolog 1
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
CCND1 cyclin D1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CIR1 corepressor interacting with RBPJ, 1
CREBBP CREB binding protein
CTBP1 C-terminal binding protein 1
CTBP2 C-terminal binding protein 2
CUL1 cullin 1
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DTX1 deltex 1, E3 ubiquitin ligase
DTX2 deltex 2, E3 ubiquitin ligase
DTX3 deltex 3, E3 ubiquitin ligase
DTX3L deltex 3 like, E3 ubiquitin ligase
DTX4 deltex 4, E3 ubiquitin ligase
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
EP300 E1A binding protein p300
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHL1 four and a half LIM domains 1
GATA3 GATA binding protein 3
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HES6 hes family bHLH transcription factor 6
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
INPP5K inositol polyphosphate-5-phosphatase K
ITCH itchy E3 ubiquitin protein ligase
JAG1 jagged 1
JAG2 jagged 2
JAK2 Janus kinase 2
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LCK LCK proto-oncogene, Src family tyrosine kinase
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MAGEA1 melanoma antigen family A1
MAML1 mastermind-like 1 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MAPT microtubule-associated protein tau
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NCSTN nicastrin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NUMB numb homolog (Drosophila)
NUMBL numb homolog (Drosophila)-like
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
PTCRA pre T-cell antigen receptor alpha
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RING1 ring finger protein 1
SAP30 Sin3A-associated protein, 30kDa
SKP1 S-phase kinase-associated protein 1
SNW1 SNW domain containing 1
SPEN spen family transcriptional repressor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNF tumor necrosis factor