Notch signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007219)
External Link http://amigo.geneontology.org/amigo/term/GO:0007219
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Genes

43 genes participating in the Notch signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
ASCL1 achaete-scute family bHLH transcription factor 1
BMP2 bone morphogenetic protein 2
CFAP58 cilia and flagella associated protein 58
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DTX1 deltex 1, E3 ubiquitin ligase
DTX2 deltex 2, E3 ubiquitin ligase
DTX3 deltex 3, E3 ubiquitin ligase
DTX3L deltex 3 like, E3 ubiquitin ligase
DTX4 deltex 4, E3 ubiquitin ligase
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GMDS GDP-mannose 4,6-dehydratase
HES5 hes family bHLH transcription factor 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HOXD3 homeobox D3
JAG1 jagged 1
JAG2 jagged 2
LOC102724023 ES1 protein homolog, mitochondrial
MAML1 mastermind-like 1 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MIB1 mindbomb E3 ubiquitin protein ligase 1
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NRARP NOTCH-regulated ankyrin repeat protein
POFUT1 protein O-fucosyltransferase 1
PSEN1 presenilin 1
PSEN2 presenilin 2
RBPJ recombination signal binding protein for immunoglobulin kappa J region
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SORBS2 sorbin and SH3 domain containing 2
SUSD5 sushi domain containing 5
ZNF423 zinc finger protein 423