Notch signaling Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP61.html
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Genes

54 proteins participating in the Notch signaling pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AKT1 v-akt murine thymoma viral oncogene homolog 1
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
CIR1 corepressor interacting with RBPJ, 1
CUL1 cullin 1
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DTX1 deltex 1, E3 ubiquitin ligase
EP300 E1A binding protein p300
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHL1 four and a half LIM domains 1
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HES6 hes family bHLH transcription factor 6
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
ITCH itchy E3 ubiquitin protein ligase
JAG1 jagged 1
JAG2 jagged 2
JAK2 Janus kinase 2
LCK LCK proto-oncogene, Src family tyrosine kinase
MAGEA1 melanoma antigen family A1
MAML1 mastermind-like 1 (Drosophila)
MAML2 mastermind-like 2 (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NCSTN nicastrin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NUMB numb homolog (Drosophila)
NUMBL numb homolog (Drosophila)-like
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RING1 ring finger protein 1
SAP30 Sin3A-associated protein, 30kDa
SKP1 S-phase kinase-associated protein 1
SNW1 SNW domain containing 1
SPEN spen family transcriptional repressor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)