Nuclear Cataract Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A nuclear cataract is an opacity or clouding that develops in the lens nucleus. That is, a nuclear cataract is one that is located in the center of the lens. The nucleus tends to darken changing from clear to yellow and sometimes brown. (Human Phenotype Ontology, HP_0100018)
External Link https://www.disgenet.org/browser/0/1/0/C0392557
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Genes

36 genes associated with the disease Nuclear Cataract in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
BFSP1 beaded filament structural protein 1, filensin
BLM Bloom syndrome, RecQ helicase-like
C21ORF2 chromosome 21 open reading frame 2
CHMP4B charged multivesicular body protein 4B
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CRYBA1 crystallin, beta A1
CRYBA2 crystallin, beta A2
CRYBB1 crystallin, beta B1
CRYBB2 crystallin, beta B2
CRYBB3 crystallin, beta B3
CRYGC crystallin, gamma C
CRYGD crystallin, gamma D
ELANE elastase, neutrophil expressed
EPHA2 EPH receptor A2
ERCC6 excision repair cross-complementation group 6
FTL ferritin, light polypeptide
FTO fat mass and obesity associated
FYCO1 FYVE and coiled-coil domain containing 1
GJA3 gap junction protein, alpha 3, 46kDa
GJA8 gap junction protein, alpha 8, 50kDa
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
HSF4 heat shock transcription factor 4
IRF1 interferon regulatory factor 1
LMNA lamin A/C
MIP major intrinsic protein of lens fiber
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
PRDX6 peroxiredoxin 6
RNF149 ring finger protein 149
SCAPER S-phase cyclin A-associated protein in the ER
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
TGM2 transglutaminase 2
UNC45B unc-45 homolog B (C. elegans)
WFS1 Wolfram syndrome 1 (wolframin)
WRN Werner syndrome, RecQ helicase-like