Nucleus Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. (Gene Ontology, GO_0005634)
External Link http://amigo.geneontology.org/amigo/term/GO:0005634
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Genes

1000 proteins co-occuring with the Nucleus cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4.0
IL1B interleukin 1, beta 4.0
TNF tumor necrosis factor 4.0
JUN jun proto-oncogene 4.0
IFNG interferon, gamma 4.0
TP53 tumor protein p53 4.0
GAPDH glyceraldehyde-3-phosphate dehydrogenase 4.0
TGFB1 transforming growth factor, beta 1 4.0
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 4.0
CASP3 caspase 3, apoptosis-related cysteine peptidase 4.0
AKT1 v-akt murine thymoma viral oncogene homolog 1 4.0
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 4.0
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 4.0
IL6 interleukin 6 4.0
TLR4 toll-like receptor 4 4.0
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 4.0
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4.0
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.0
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 4.0
BCL2 B-cell CLL/lymphoma 2 3.993
FOS FBJ murine osteosarcoma viral oncogene homolog 3.983
ESR1 estrogen receptor 1 3.95
INS insulin 3.949
CD4 CD4 molecule 3.937
MTOR mechanistic target of rapamycin (serine/threonine kinase) 3.933
IL10 interleukin 10 3.931
PPARG peroxisome proliferator-activated receptor gamma 3.922
CXCL8 chemokine (C-X-C motif) ligand 8 3.892
CCND1 cyclin D1 3.886
CD8A CD8a molecule 3.871
CCL2 chemokine (C-C motif) ligand 2 3.841
EGFR epidermal growth factor receptor 3.841
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 3.837
H3-5 H3.5 histone 3.834
H3-4 H3.4 histone, cluster member 3.834
H3-7 H3.7 histone (putative) 3.833
MAPK3 mitogen-activated protein kinase 3 3.826
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.822
IL1A interleukin 1, alpha 3.792
MYD88 myeloid differentiation primary response 88 3.791
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 3.789
ERBB2 erb-b2 receptor tyrosine kinase 2 3.764
HMOX1 heme oxygenase 1 3.761
MMP9 matrix metallopeptidase 9 3.752
CREB1 cAMP responsive element binding protein 1 3.729
CDKN2A cyclin-dependent kinase inhibitor 2A 3.728
PTEN phosphatase and tensin homolog 3.725
STAT1 signal transducer and activator of transcription 1, 91kDa 3.723
EGF epidermal growth factor 3.718
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 3.716
IL4 interleukin 4 3.707
ANXA5 annexin A5 3.706
IL2 interleukin 2 3.7
PCNA proliferating cell nuclear antigen 3.697
SIRT1 sirtuin 1 3.697
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 3.686
BAX BCL2-associated X protein 3.682
GSK3B glycogen synthase kinase 3 beta 3.679
ATM ATM serine/threonine kinase 3.673
NFE2L2 nuclear factor, erythroid 2-like 2 3.671
TLR2 toll-like receptor 2 3.665
PTPRC protein tyrosine phosphatase, receptor type, C 3.664
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.642
PARP1 poly (ADP-ribose) polymerase 1 3.63
ICAM1 intercellular adhesion molecule 1 3.629
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 3.628
KEAP1 kelch-like ECH-associated protein 1 3.616
BRCA1 breast cancer 1, early onset 3.615
IFNB1 interferon, beta 1, fibroblast 3.612
REL v-rel avian reticuloendotheliosis viral oncogene homolog 3.603
PGR progesterone receptor 3.597
PPARA peroxisome proliferator-activated receptor alpha 3.596
HDAC9 histone deacetylase 9 3.594
CD34 CD34 molecule 3.586
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 3.586
CHUK conserved helix-loop-helix ubiquitous kinase 3.583
IRF3 interferon regulatory factor 3 3.582
CD274 CD274 molecule 3.58
SOX2 SRY (sex determining region Y)-box 2 3.577
IGF1 insulin-like growth factor 1 (somatomedin C) 3.572
JAK2 Janus kinase 2 3.568
LEP leptin 3.568
SMAD2 SMAD family member 2 3.567
IFNA1 interferon, alpha 1 3.562
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 3.559
SMAD4 SMAD family member 4 3.558
BCL2L1 BCL2-like 1 3.556
PECAM1 platelet/endothelial cell adhesion molecule 1 3.554
SMAD3 SMAD family member 3 3.552
FN1 fibronectin 1 3.54
CD44 CD44 molecule (Indian blood group) 3.54
IL18 interleukin 18 3.536
EP300 E1A binding protein p300 3.535
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 3.531
POU5F1 POU class 5 homeobox 1 3.529
FOXO1 forkhead box O1 3.525
FOXP3 forkhead box P3 3.523
H2BC21 H2B clustered histone 21 3.52
POMC proopiomelanocortin 3.519
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 3.516
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.513
CASP1 caspase 1, apoptosis-related cysteine peptidase 3.512
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3.51
HDAC1 histone deacetylase 1 3.496
RUNX2 runt-related transcription factor 2 3.496
CYCS cytochrome c, somatic 3.496
CDPF1 cysteine-rich, DPF motif domain containing 1 3.485
DICER1 dicer 1, ribonuclease type III 3.485
VCAM1 vascular cell adhesion molecule 1 3.482
CDK4 cyclin-dependent kinase 4 3.482
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 3.481
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 3.476
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.474
CASP8 caspase 8, apoptosis-related cysteine peptidase 3.474
BDNF brain-derived neurotrophic factor 3.473
BRAF B-Raf proto-oncogene, serine/threonine kinase 3.47
NANOG Nanog homeobox 3.467
CD68 CD68 molecule 3.467
LMNB1 lamin B1 3.464
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 3.46
MAPK8 mitogen-activated protein kinase 8 3.458
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 3.458
CCL5 chemokine (C-C motif) ligand 5 3.456
MMP2 matrix metallopeptidase 2 3.448
HSPA4 heat shock 70kDa protein 4 3.448
SNAI1 snail family zinc finger 1 3.446
ESR2 estrogen receptor 2 (ER beta) 3.446
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 3.445
FOXO3 forkhead box O3 3.442
BIRC5 baculoviral IAP repeat containing 5 3.44
TLR3 toll-like receptor 3 3.44
CDK2 cyclin-dependent kinase 2 3.439
NOTCH1 notch 1 3.436
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 3.435
RAD50 RAD50 homolog (S. cerevisiae) 3.432
CASP9 caspase 9, apoptosis-related cysteine peptidase 3.431
IL13 interleukin 13 3.428
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.426
GFAP glial fibrillary acidic protein 3.426
DNTT DNA nucleotidylexotransferase 3.422
DNMT1 DNA (cytosine-5-)-methyltransferase 1 3.414
DROSHA drosha, ribonuclease type III 3.413
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.411
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 3.408
SREBF1 sterol regulatory element binding transcription factor 1 3.406
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 3.406
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.405
HMGB1 high mobility group box 1 3.403
CXCR4 chemokine (C-X-C motif) receptor 4 3.392
CDK1 cyclin-dependent kinase 1 3.392
PRKDC protein kinase, DNA-activated, catalytic polypeptide 3.391
RIGI RNA sensor RIG-I 3.383
MPO myeloperoxidase 3.382
STAT5B signal transducer and activator of transcription 5B 3.38
BRCA2 breast cancer 2, early onset 3.379
NQO1 NAD(P)H dehydrogenase, quinone 1 3.377
RUNX1 runt-related transcription factor 1 3.375
NPY neuropeptide Y 3.374
JAK1 Janus kinase 1 3.373
CCNL2 cyclin L2 3.373
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 3.372
STAT5A signal transducer and activator of transcription 5A 3.37
KAT2B K(lysine) acetyltransferase 2B 3.37
ADIPOQ adiponectin, C1Q and collagen domain containing 3.37
H2AC20 H2A clustered histone 20 3.37
E2F1 E2F transcription factor 1 3.367
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 3.366
APOE apolipoprotein E 3.364
AHR aryl hydrocarbon receptor 3.363
CD40 CD40 molecule, TNF receptor superfamily member 5 3.36
MYB v-myb avian myeloblastosis viral oncogene homolog 3.357
IRAK1 interleukin-1 receptor-associated kinase 1 3.355
CD19 CD19 molecule 3.353
AIF1 allograft inflammatory factor 1 3.351
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 3.351
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 3.351
LGALS4 lectin, galactoside-binding, soluble, 4 3.351
TLR9 toll-like receptor 9 3.35
KLF4 Kruppel-like factor 4 (gut) 3.349
DNAH8 dynein, axonemal, heavy chain 8 3.349
EGR1 early growth response 1 3.34
RAD51 RAD51 recombinase 3.34
CTLA4 cytotoxic T-lymphocyte-associated protein 4 3.335
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 3.335
CD86 CD86 molecule 3.334
XPO1 exportin 1 3.331
MAP2K1 mitogen-activated protein kinase kinase 1 3.331
SOX9 SRY (sex determining region Y)-box 9 3.331
SLCO6A1 solute carrier organic anion transporter family, member 6A1 3.329
TERT telomerase reverse transcriptase 3.325
CXCL12 chemokine (C-X-C motif) ligand 12 3.319
NR1I2 nuclear receptor subfamily 1, group I, member 2 3.318
BGLAP bone gamma-carboxyglutamate (gla) protein 3.316
TBP TATA box binding protein 3.316
GPX3 glutathione peroxidase 3 3.315
AXIN1 axin 1 3.314
GPX2 glutathione peroxidase 2 3.314
GCG glucagon 3.313
TP53BP1 tumor protein p53 binding protein 1 3.312
CHEK1 checkpoint kinase 1 3.312
PRKACB protein kinase, cAMP-dependent, catalytic, beta 3.308
HDAC2 histone deacetylase 2 3.307
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 3.306
RARA retinoic acid receptor, alpha 3.304
GATA3 GATA binding protein 3 3.304
CCNA2 cyclin A2 3.303
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.303
CCNB1 cyclin B1 3.302
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 3.3
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 3.299
TLR7 toll-like receptor 7 3.299
RHOA ras homolog family member A 3.297
H2AX H2A.X variant histone 3.293
GPX7 glutathione peroxidase 7 3.292
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 3.29
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 3.287
GPX5 glutathione peroxidase 5 3.287
GPX8 glutathione peroxidase 8 (putative) 3.287
GPX6 glutathione peroxidase 6 3.286
CCL3 chemokine (C-C motif) ligand 3 3.284
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 3.28
KDR kinase insert domain receptor 3.28
APP amyloid beta (A4) precursor protein 3.277
CTCF CCCTC-binding factor (zinc finger protein) 3.276
HDAC3 histone deacetylase 3 3.276
IRF1 interferon regulatory factor 1 3.276
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 3.274
NCAM1 neural cell adhesion molecule 1 3.273
IRF7 interferon regulatory factor 7 3.273
CD28 CD28 molecule 3.271
SHH sonic hedgehog 3.27
MYH14 myosin, heavy chain 14, non-muscle 3.27
ZEB1 zinc finger E-box binding homeobox 1 3.265
LMNA lamin A/C 3.265
TJP1 tight junction protein 1 3.265
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 3.264
KAT2A K(lysine) acetyltransferase 2A 3.258
CSF1 colony stimulating factor 1 (macrophage) 3.257
CREBBP CREB binding protein 3.256
CD80 CD80 molecule 3.254
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 3.252
ACE angiotensin I converting enzyme 3.252
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 3.252
CRH corticotropin releasing hormone 3.251
GLB1 galactosidase, beta 1 3.25
TBK1 TANK-binding kinase 1 3.25
FGF7 fibroblast growth factor 7 3.25
IGF1R insulin-like growth factor 1 receptor 3.25
GATA4 GATA binding protein 4 3.25
CALM3 calmodulin 3 (phosphorylase kinase, delta) 3.249
IL5 interleukin 5 3.249
CCN2 cellular communication network factor 2 3.249
CSF3 colony stimulating factor 3 (granulocyte) 3.243
FGF8 fibroblast growth factor 8 (androgen-induced) 3.242
PPARD peroxisome proliferator-activated receptor delta 3.241
NGF nerve growth factor (beta polypeptide) 3.239
LEF1 lymphoid enhancer-binding factor 1 3.239
FASLG Fas ligand (TNF superfamily, member 6) 3.237
MCL1 myeloid cell leukemia 1 3.236
FGF10 fibroblast growth factor 10 3.236
TCHP trichoplein, keratin filament binding 3.235
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 3.235
MMP3 matrix metallopeptidase 3 3.233
FGF4 fibroblast growth factor 4 3.233
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 3.232
MAPK1 mitogen-activated protein kinase 1 3.229
YAP1 Yes-associated protein 1 3.228
IFIH1 interferon induced with helicase C domain 1 3.227
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B 3.227
MLH1 mutL homolog 1 3.225
BECN1 beclin 1, autophagy related 3.222
MYOD1 myogenic differentiation 1 3.221
BCL6 B-cell CLL/lymphoma 6 3.22
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 3.22
NES nestin 3.22
MRC1 mannose receptor, C type 1 3.219
SOCS3 suppressor of cytokine signaling 3 3.219
AGRP agouti related neuropeptide 3.218
SPI1 Spi-1 proto-oncogene 3.216
INSR insulin receptor 3.214
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 3.214
ACP5 acid phosphatase 5, tartrate resistant 3.214
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 3.212
SCARB1 scavenger receptor class B, member 1 3.212
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 3.211
SNAI2 snail family zinc finger 2 3.21
FGF9 fibroblast growth factor 9 3.21
SUZ12 SUZ12 polycomb repressive complex 2 subunit 3.207
CCNA1 cyclin A1 3.206
SST somatostatin 3.206
CALML3 calmodulin-like 3 3.203
CALML5 calmodulin-like 5 3.202
FGF5 fibroblast growth factor 5 3.202
CALML4 calmodulin-like 4 3.201
CALML6 calmodulin-like 6 3.2
WT1 Wilms tumor 1 3.2
STAT2 signal transducer and activator of transcription 2, 113kDa 3.2
CDK6 cyclin-dependent kinase 6 3.199
IL1R1 interleukin 1 receptor, type I 3.199
DGCR8 DGCR8 microprocessor complex subunit 3.198
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.198
FLT3 fms-related tyrosine kinase 3 3.198
AGO2 argonaute RISC catalytic component 2 3.196
FGF3 fibroblast growth factor 3 3.195
BCL2L11 BCL2-like 11 (apoptosis facilitator) 3.193
FGF18 fibroblast growth factor 18 3.193
LOX lysyl oxidase 3.192
BRD4 bromodomain containing 4 3.191
YY1 YY1 transcription factor 3.19
ALK anaplastic lymphoma receptor tyrosine kinase 3.19
FGF17 fibroblast growth factor 17 3.188
NCOR1 nuclear receptor corepressor 1 3.188
EPCAM epithelial cell adhesion molecule 3.187
ACE2 angiotensin I converting enzyme 2 3.187
PROM1 prominin 1 3.187
CD36 CD36 molecule (thrombospondin receptor) 3.186
NF1 neurofibromin 1 3.186
TGFBR1 transforming growth factor, beta receptor 1 3.185
SYP synaptophysin 3.184
FGF20 fibroblast growth factor 20 3.183
WNT3A wingless-type MMTV integration site family, member 3A 3.182
MSH6 mutS homolog 6 3.181
TH tyrosine hydroxylase 3.178
FGF6 fibroblast growth factor 6 3.178
IRS1 insulin receptor substrate 1 3.178
SELE selectin E 3.178
FGF16 fibroblast growth factor 16 3.177
MMP13 matrix metallopeptidase 13 3.177
PDCD1 programmed cell death 1 3.175
TARDBP TAR DNA binding protein 3.174
EPAS1 endothelial PAS domain protein 1 3.173
FGF22 fibroblast growth factor 22 3.173
NR4A1 nuclear receptor subfamily 4, group A, member 1 3.172
H4C7 H4 clustered histone 7 3.172
EDN1 endothelin 1 3.171
BMP4 bone morphogenetic protein 4 3.169
RBPJ recombination signal binding protein for immunoglobulin kappa J region 3.169
JUND jun D proto-oncogene 3.169
KRT7 keratin 7, type II 3.167
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3.167
MSH2 mutS homolog 2 3.167
COMMD3-BMI1 COMMD3-BMI1 readthrough 3.166
MMUT methylmalonyl-CoA mutase 3.166
IL33 interleukin 33 3.165
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 3.159
SCARB2 scavenger receptor class B, member 2 3.158
ARID1A AT rich interactive domain 1A (SWI-like) 3.158
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 3.157
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 3.157
DKK1 dickkopf WNT signaling pathway inhibitor 1 3.156
XPO5 exportin 5 3.155
GLI1 GLI family zinc finger 1 3.155
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 3.154
THY1 Thy-1 cell surface antigen 3.153
BMP2 bone morphogenetic protein 2 3.151
CCL4 chemokine (C-C motif) ligand 4 3.15
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3.15
BMAL1 basic helix-loop-helix ARNT like 1 3.149
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 3.147
KDM1A lysine (K)-specific demethylase 1A 3.146
MAPK14 mitogen-activated protein kinase 14 3.146
XPR1 xenotropic and polytropic retrovirus receptor 1 3.146
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 3.146
SMAD7 SMAD family member 7 3.145
PKM pyruvate kinase, muscle 3.144
IL3 interleukin 3 3.144
COL1A1 collagen, type I, alpha 1 3.141
SRSF2 serine/arginine-rich splicing factor 2 3.139
HRAS Harvey rat sarcoma viral oncogene homolog 3.138
IL22 interleukin 22 3.137
CD40LG CD40 ligand 3.135
IGF2 insulin-like growth factor 2 3.133
JAG1 jagged 1 3.132
TET2 tet methylcytosine dioxygenase 2 3.129
FOXM1 forkhead box M1 3.128
GHRL ghrelin/obestatin prepropeptide 3.128
ATRX alpha thalassemia/mental retardation syndrome X-linked 3.126
MAVS mitochondrial antiviral signaling protein 3.126
IRF4 interferon regulatory factor 4 3.125
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 3.124
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 3.123
OCLN occludin 3.123
CCR2 chemokine (C-C motif) receptor 2 3.122
SOCS1 suppressor of cytokine signaling 1 3.121
TIMP1 TIMP metallopeptidase inhibitor 1 3.12
AXIN2 axin 2 3.12
CD163 CD163 molecule 3.12
FUS FUS RNA binding protein 3.119
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 3.119
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 3.117
TRAF3 TNF receptor-associated factor 3 3.116
PDGFRB platelet-derived growth factor receptor, beta polypeptide 3.115
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 3.115
SOD1 superoxide dismutase 1, soluble 3.114
POTEF POTE ankyrin domain family, member F 3.114
FOSL1 FOS-like antigen 1 3.113
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 3.112
NOD2 nucleotide-binding oligomerization domain containing 2 3.111
BCR breakpoint cluster region 3.109
CDX2 caudal type homeobox 2 3.109
PIWIL1 piwi-like RNA-mediated gene silencing 1 3.108
PAX6 paired box 6 3.105
H1-0 H1.0 linker histone 3.105
CTSK cathepsin K 3.104
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 3.103
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.103
SYK spleen tyrosine kinase 3.103
XBP1 X-box binding protein 1 3.102
TYK2 tyrosine kinase 2 3.102
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 3.102
IL7 interleukin 7 3.102
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 3.101
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 3.099
PIWIL4 piwi-like RNA-mediated gene silencing 4 3.099
IL15 interleukin 15 3.098
CDC42 cell division cycle 42 3.097
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.097
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.097
KRT5 keratin 5, type II 3.094
OXT oxytocin/neurophysin I prepropeptide 3.094
HPRT1 hypoxanthine phosphoribosyltransferase 1 3.094
CDK9 cyclin-dependent kinase 9 3.094
SRSF1 serine/arginine-rich splicing factor 1 3.092
TAC1 tachykinin, precursor 1 3.09
FABP4 fatty acid binding protein 4, adipocyte 3.09
TBX21 T-box 21 3.09
IDO1 indoleamine 2,3-dioxygenase 1 3.09
ELAVL1 ELAV like RNA binding protein 1 3.088
SIRT2 sirtuin 2 3.087
CD38 CD38 molecule 3.086
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 3.086
CSF1R colony stimulating factor 1 receptor 3.082
ATF3 activating transcription factor 3 3.082
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 3.081
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.08
CGAS cyclic GMP-AMP synthase 3.078
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 3.077
FGF13 fibroblast growth factor 13 3.077
MYOG myogenin (myogenic factor 4) 3.076
PPIG peptidylprolyl isomerase G (cyclophilin G) 3.075
WNT5A wingless-type MMTV integration site family, member 5A 3.075
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.073
SOD2 superoxide dismutase 2, mitochondrial 3.072
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.072
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 3.071
CFLAR CASP8 and FADD-like apoptosis regulator 3.071
SQSTM1 sequestosome 1 3.071
HCRT hypocretin (orexin) neuropeptide precursor 3.069
HNF1A HNF1 homeobox A 3.069
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 3.067
FOSB FBJ murine osteosarcoma viral oncogene homolog B 3.067
LATS1 large tumor suppressor kinase 1 3.067
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.067
STK11 serine/threonine kinase 11 3.064
B2M beta-2-microglobulin 3.064
PRL prolactin 3.063
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 3.062
ATF6 activating transcription factor 6 3.061
IRF9 interferon regulatory factor 9 3.06
HDAC4 histone deacetylase 4 3.059
PLK1 polo-like kinase 1 3.059
NR1D1 nuclear receptor subfamily 1, group D, member 1 3.058
FGFR1 fibroblast growth factor receptor 1 3.058
CCL20 chemokine (C-C motif) ligand 20 3.057
CXCL9 chemokine (C-X-C motif) ligand 9 3.055
AGER advanced glycosylation end product-specific receptor 3.053
CYBB cytochrome b-245, beta polypeptide 3.051
TWIST1 twist family bHLH transcription factor 1 3.051
BIRC3 baculoviral IAP repeat containing 3 3.051
LCK LCK proto-oncogene, Src family tyrosine kinase 3.05
PAX5 paired box 5 3.05
CCR7 chemokine (C-C motif) receptor 7 3.05
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 3.049
TLR5 toll-like receptor 5 3.049
IFNAR1 interferon (alpha, beta and omega) receptor 1 3.048
CDC20 cell division cycle 20 3.047
FOXA1 forkhead box A1 3.046
BIRC2 baculoviral IAP repeat containing 2 3.044
CD5 CD5 molecule 3.044
PTPN11 protein tyrosine phosphatase, non-receptor type 11 3.042
ENG endoglin 3.042
CDH5 cadherin 5, type 2 (vascular endothelium) 3.041
GATA2 GATA binding protein 2 3.041
NR4A2 nuclear receptor subfamily 4, group A, member 2 3.04
FOXA2 forkhead box A2 3.04
RB1 retinoblastoma 1 3.038
TFRC transferrin receptor 3.038
KRT19 keratin 19, type I 3.037
VWF von Willebrand factor 3.036
SIRT3 sirtuin 3 3.036
PTK2 protein tyrosine kinase 2 3.035
BANF1 barrier to autointegration factor 1 3.034
SP7 Sp7 transcription factor 3.034
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 3.034
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 3.033
EXO1 exonuclease 1 3.031
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 3.03
TGFB2 transforming growth factor, beta 2 3.03
BTK Bruton agammaglobulinemia tyrosine kinase 3.03
CD69 CD69 molecule 3.029
KMT2A lysine (K)-specific methyltransferase 2A 3.028
FADD Fas (TNFRSF6)-associated via death domain 3.026
CXCL2 chemokine (C-X-C motif) ligand 2 3.025
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 3.025
FBL fibrillarin 3.024
NFE2 nuclear factor, erythroid 2 3.023
TFEB transcription factor EB 3.023
CD24 CD24 molecule 3.022
JAK3 Janus kinase 3 3.021
ATG5 autophagy related 5 3.021
ERVW-1 endogenous retrovirus group W, member 1 3.021
RARS1 arginyl-tRNA synthetase 1 3.02
NOX4 NADPH oxidase 4 3.019
MUC1 mucin 1, cell surface associated 3.019
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 3.018
METTL3 methyltransferase like 3 3.018
CAV1 caveolin 1, caveolae protein, 22kDa 3.017
TFAM transcription factor A, mitochondrial 3.017
IRAK4 interleukin-1 receptor-associated kinase 4 3.017
RBBP8 retinoblastoma binding protein 8 3.016
CUL3 cullin 3 3.016
WNT1 wingless-type MMTV integration site family, member 1 3.014
MX1 MX dynamin-like GTPase 1 3.014
TLR1 toll-like receptor 1 3.014
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 3.012
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 3.012
SRF serum response factor (c-fos serum response element-binding transcription factor) 3.011
LAMP1 lysosomal-associated membrane protein 1 3.01
LY96 lymphocyte antigen 96 3.009
PTCH1 patched 1 3.008
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 3.007
JAG2 jagged 2 3.007
NR5A1 nuclear receptor subfamily 5, group A, member 1 3.005
ACAN aggrecan 3.004
SOX10 SRY (sex determining region Y)-box 10 3.004
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 3.002
GSR glutathione reductase 3.002
SIRT6 sirtuin 6 3.001
VIM vimentin 3.001
SUMO1 small ubiquitin-like modifier 1 3.0
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.998
FASN fatty acid synthase 2.997
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 2.996
CRY1 cryptochrome circadian clock 1 2.996
NKX2-1 NK2 homeobox 1 2.996
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.994
KISS1 KiSS-1 metastasis-suppressor 2.994
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.994
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 2.994
IFNA2 interferon, alpha 2 2.993
CISH cytokine inducible SH2-containing protein 2.991
OLIG2 oligodendrocyte lineage transcription factor 2 2.991
VCL vinculin 2.99
GCLC glutamate-cysteine ligase, catalytic subunit 2.99
MAPT microtubule-associated protein tau 2.989
GJA1 gap junction protein, alpha 1, 43kDa 2.989
IL7R interleukin 7 receptor 2.989
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.988
RET ret proto-oncogene 2.988
ISG15 ISG15 ubiquitin-like modifier 2.988
PRKCA protein kinase C, alpha 2.987
MEF2C myocyte enhancer factor 2C 2.984
SDC1 syndecan 1 2.983
KAT5 K(lysine) acetyltransferase 5 2.983
TBL1X transducin (beta)-like 1X-linked 2.983
CCND2 cyclin D2 2.981
CALR calreticulin 2.98
SETD2 SET domain containing 2 2.98
FOSL2 FOS-like antigen 2 2.98
HSPB3 heat shock 27kDa protein 3 2.979
CLOCK clock circadian regulator 2.979
NOTCH2 notch 2 2.978
HAVCR2 hepatitis A virus cellular receptor 2 2.978
MECP2 methyl CpG binding protein 2 2.978
RAG1 recombination activating gene 1 2.978
KITLG KIT ligand 2.977
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.975
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.975
NR0B2 nuclear receptor subfamily 0, group B, member 2 2.975
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 2.973
POLI polymerase (DNA directed) iota 2.973
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 2.973
EIF4E eukaryotic translation initiation factor 4E 2.972
TGFA transforming growth factor, alpha 2.971
FLT1 fms-related tyrosine kinase 1 2.971
TOP2A topoisomerase (DNA) II alpha 170kDa 2.971
FTO fat mass and obesity associated 2.97
MMP7 matrix metallopeptidase 7 2.969
NT5E 5'-nucleotidase, ecto (CD73) 2.969
MITF microphthalmia-associated transcription factor 2.969
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 2.969
AURKB aurora kinase B 2.968
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.967
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.967
TLR8 toll-like receptor 8 2.967
ERN1 endoplasmic reticulum to nucleus signaling 1 2.966
SELL selectin L 2.966
SETD1A SET domain containing 1A 2.965
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.965
RXRA retinoid X receptor, alpha 2.964
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 2.964
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 2.963
KRT20 keratin 20, type I 2.962
HDAC6 histone deacetylase 6 2.961
EHMT2 euchromatic histone-lysine N-methyltransferase 2 2.96
MGMT O-6-methylguanine-DNA methyltransferase 2.959
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 2.958
CTRL chymotrypsin-like 2.958
PER2 period circadian clock 2 2.956
HSPB1 heat shock 27kDa protein 1 2.955
CDKN3 cyclin-dependent kinase inhibitor 3 2.954
SREBF2 sterol regulatory element binding transcription factor 2 2.954
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.954
CXCR2 chemokine (C-X-C motif) receptor 2 2.953
LIF leukemia inhibitory factor 2.952
RAD52 RAD52 homolog (S. cerevisiae) 2.951
CYLD cylindromatosis (turban tumor syndrome) 2.951
ZEB2 zinc finger E-box binding homeobox 2 2.951
RETNLB resistin like beta 2.95
EWSR1 EWS RNA-binding protein 1 2.949
GSDMD gasdermin D 2.948
PAX8 paired box 8 2.948
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 2.947
TRADD TNFRSF1A-associated via death domain 2.946
BCL10 B-cell CLL/lymphoma 10 2.946
LRP6 low density lipoprotein receptor-related protein 6 2.945
TMC6 transmembrane channel-like 6 2.945
GPX4 glutathione peroxidase 4 2.945
MAP3K7 mitogen-activated protein kinase kinase kinase 7 2.944
IRF8 interferon regulatory factor 8 2.944
GRB2 growth factor receptor-bound protein 2 2.944
F3 coagulation factor III (thromboplastin, tissue factor) 2.944
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 2.943
U2AF1 U2 small nuclear RNA auxiliary factor 1 2.943
ATG7 autophagy related 7 2.943
CALB2 calbindin 2 2.942
RARB retinoic acid receptor, beta 2.94
FANCD2 Fanconi anemia, complementation group D2 2.939
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.939
DPP4 dipeptidyl-peptidase 4 2.939
GADD45A growth arrest and DNA-damage-inducible, alpha 2.938
ISL1 ISL LIM homeobox 1 2.935
ERLN endoregulin 2.935
AKT2 v-akt murine thymoma viral oncogene homolog 2 2.933
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.932
APAF1 apoptotic peptidase activating factor 1 2.931
NOD1 nucleotide-binding oligomerization domain containing 1 2.93
AGTR1 angiotensin II receptor, type 1 2.93
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.929
DDIT3 DNA-damage-inducible transcript 3 2.928
PRDM1 PR domain containing 1, with ZNF domain 2.928
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 2.928
ERBB3 erb-b2 receptor tyrosine kinase 3 2.928
YBX1 Y box binding protein 1 2.926
KDM6A lysine (K)-specific demethylase 6A 2.926
ENO2 enolase 2 (gamma, neuronal) 2.925
DVL1 dishevelled segment polarity protein 1 2.925
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 2.924
LIN28A lin-28 homolog A (C. elegans) 2.923
LDHA lactate dehydrogenase A 2.923
H2AZ1 H2A.Z variant histone 1 2.923
NPPA natriuretic peptide A 2.922
ERCC1 excision repair cross-complementation group 1 2.921
ADAR adenosine deaminase, RNA-specific 2.921
IL6R interleukin 6 receptor 2.92
CD276 CD276 molecule 2.92
TMPRSS2 transmembrane protease, serine 2 2.92
CXCR3 chemokine (C-X-C motif) receptor 3 2.919
TRPV1 transient receptor potential cation channel, subfamily V, member 1 2.919
KLF2 Kruppel-like factor 2 2.918
ELANE elastase, neutrophil expressed 2.918
RUNX3 runt-related transcription factor 3 2.918
MAPK11 mitogen-activated protein kinase 11 2.915
GPER1 G protein-coupled estrogen receptor 1 2.915
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.915
IL11 interleukin 11 2.914
KRT8 keratin 8, type II 2.914
PVALB parvalbumin 2.914
FGFR2 fibroblast growth factor receptor 2 2.914
ASXL1 additional sex combs like transcriptional regulator 1 2.913
BMP7 bone morphogenetic protein 7 2.913
RBM8A RNA binding motif protein 8A 2.911
CLDN1 claudin 1 2.91
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2.908
GLI2 GLI family zinc finger 2 2.908
LCN2 lipocalin 2 2.907
CRY2 cryptochrome circadian clock 2 2.907
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.906
ETV6 ets variant 6 2.906
GPBAR1 G protein-coupled bile acid receptor 1 2.905
KRT14 keratin 14, type I 2.904
HMGA2 high mobility group AT-hook 2 2.904
NUCB1 nucleobindin 1 2.904
HSPB2 heat shock 27kDa protein 2 2.903
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 2.902
TET1 tet methylcytosine dioxygenase 1 2.902
PLAU plasminogen activator, urokinase 2.901
S100B S100 calcium binding protein B 2.898
RETN resistin 2.897
HDAC8 histone deacetylase 8 2.897
LAG3 lymphocyte-activation gene 3 2.897
PAX7 paired box 7 2.897
PALB2 partner and localizer of BRCA2 2.897
MAPK12 mitogen-activated protein kinase 12 2.896
SKP1 S-phase kinase-associated protein 1 2.896
PDYN prodynorphin 2.896
CKM creatine kinase, muscle 2.895
BCL3 B-cell CLL/lymphoma 3 2.894
KRT18 keratin 18, type I 2.894
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.894
FYN FYN proto-oncogene, Src family tyrosine kinase 2.894
TG thyroglobulin 2.893
ERBB4 erb-b2 receptor tyrosine kinase 4 2.893
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.892
ULK1 unc-51 like autophagy activating kinase 1 2.891
AXL AXL receptor tyrosine kinase 2.891
CD79A CD79a molecule, immunoglobulin-associated alpha 2.89
ESRRA estrogen-related receptor alpha 2.889
CXCL11 chemokine (C-X-C motif) ligand 11 2.888
GATA6 GATA binding protein 6 2.888
EOMES eomesodermin 2.887
CLDN7 claudin 7 2.887
HNRNPK heterogeneous nuclear ribonucleoprotein K 2.886
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.886
CD27 CD27 molecule 2.885
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 2.885
CARD11 caspase recruitment domain family, member 11 2.883
DAXX death-domain associated protein 2.883
SRY sex determining region Y 2.882
TSC2 tuberous sclerosis 2 2.881
IFNA17 interferon, alpha 17 2.881
ALPL alkaline phosphatase, liver/bone/kidney 2.88
CXCL5 chemokine (C-X-C motif) ligand 5 2.88
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.88
CCNT1 cyclin T1 2.879
CALB1 calbindin 1, 28kDa 2.878
CCNE1 cyclin E1 2.878
ERV3-1 endogenous retrovirus group 3, member 1 2.878
CKB creatine kinase, brain 2.878
TRIM21 tripartite motif containing 21 2.876
MAPK13 mitogen-activated protein kinase 13 2.876
TGFB3 transforming growth factor, beta 3 2.876
NR3C2 nuclear receptor subfamily 3, group C, member 2 2.876
CUL1 cullin 1 2.876
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.874
AURKA aurora kinase A 2.873
SOST sclerostin 2.873
NOTCH3 notch 3 2.872
FEN1 flap structure-specific endonuclease 1 2.872
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 2.872
GTF2B general transcription factor IIB 2.872
CD33 CD33 molecule 2.871
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.871
PHC3 polyhomeotic homolog 3 (Drosophila) 2.87
ATF4 activating transcription factor 4 2.87
THBS1 thrombospondin 1 2.87
PLG plasminogen 2.869
WRN Werner syndrome, RecQ helicase-like 2.868
MATK megakaryocyte-associated tyrosine kinase 2.868
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.867
TXNIP thioredoxin interacting protein 2.867
NAMPT nicotinamide phosphoribosyltransferase 2.865
AIM2 absent in melanoma 2 2.865
PRTN3 proteinase 3 2.864
MDC1 mediator of DNA-damage checkpoint 1 2.864
RAG2 recombination activating gene 2 2.864
CTSB cathepsin B 2.863
METTL14 methyltransferase like 14 2.863
WEE1 WEE1 G2 checkpoint kinase 2.863
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.862
CKMT1B creatine kinase, mitochondrial 1B 2.862
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.862
NOG noggin 2.862
NF2 neurofibromin 2 (merlin) 2.862
HOXA9 homeobox A9 2.86
APOB apolipoprotein B 2.86
CANX calnexin 2.859
KDM6B lysine (K)-specific demethylase 6B 2.858
IRF5 interferon regulatory factor 5 2.858
ALOX5 arachidonate 5-lipoxygenase 2.858
GLP1R glucagon-like peptide 1 receptor 2.858
CTSS cathepsin S 2.857
PDCD1LG2 programmed cell death 1 ligand 2 2.856
HSPA8 heat shock 70kDa protein 8 2.856
PGK1 phosphoglycerate kinase 1 2.855
LPL lipoprotein lipase 2.855
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.855
UBE2I ubiquitin-conjugating enzyme E2I 2.855
TBX5 T-box 5 2.855
CCL11 chemokine (C-C motif) ligand 11 2.854
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 2.853
MALT1 MALT1 paracaspase 2.853
NR5A2 nuclear receptor subfamily 5, group A, member 2 2.851
NUP98 nucleoporin 98kDa 2.851
ADAM17 ADAM metallopeptidase domain 17 2.85
TRAF1 TNF receptor-associated factor 1 2.85
COL1A2 collagen, type I, alpha 2 2.849
MAPK9 mitogen-activated protein kinase 9 2.849
G6PC1 glucose-6-phosphatase catalytic subunit 1 2.849
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 2.846
MYH11 myosin, heavy chain 11, smooth muscle 2.846
RARG retinoic acid receptor, gamma 2.845
NEUROD1 neuronal differentiation 1 2.845
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.845
LYN LYN proto-oncogene, Src family tyrosine kinase 2.844
SIRT7 sirtuin 7 2.844
PRMT5 protein arginine methyltransferase 5 2.843
ALKBH5 AlkB family member 5, RNA demethylase 2.842
IGFBP3 insulin-like growth factor binding protein 3 2.84
CCND3 cyclin D3 2.84
RAD21 RAD21 homolog (S. pombe) 2.839
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 2.838
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 2.838
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.836
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.836
TOP1 topoisomerase (DNA) I 2.836
EGR2 early growth response 2 2.835
MSTN myostatin 2.835
AREG amphiregulin 2.835
AGO1 argonaute RISC catalytic component 1 2.832
FGFR3 fibroblast growth factor receptor 3 2.832
CD63 CD63 molecule 2.831
CD1D CD1d molecule 2.831
GCLM glutamate-cysteine ligase, modifier subunit 2.831
U2AF2 U2 small nuclear RNA auxiliary factor 2 2.831
PPIA peptidylprolyl isomerase A (cyclophilin A) 2.83
SOX17 SRY (sex determining region Y)-box 17 2.83
FOXO4 forkhead box O4 2.829
TEK TEK tyrosine kinase, endothelial 2.829
EED embryonic ectoderm development 2.828
RIPK3 receptor-interacting serine-threonine kinase 3 2.827
AICDA activation-induced cytidine deaminase 2.827
SCD stearoyl-CoA desaturase (delta-9-desaturase) 2.827
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 2.827
WDR5 WD repeat domain 5 2.826
CA9 carbonic anhydrase IX 2.826
DIABLO diablo, IAP-binding mitochondrial protein 2.825
ALPP alkaline phosphatase, placental 2.824
FMR1 fragile X mental retardation 1 2.824
POLE polymerase (DNA directed), epsilon, catalytic subunit 2.824
MC4R melanocortin 4 receptor 2.824
DNA2 DNA replication helicase/nuclease 2 2.823
NGFR nerve growth factor receptor 2.823
RNF2 ring finger protein 2 2.823
ACHE acetylcholinesterase (Yt blood group) 2.823
MAPK7 mitogen-activated protein kinase 7 2.823
CXCL13 chemokine (C-X-C motif) ligand 13 2.823
SGK1 serum/glucocorticoid regulated kinase 1 2.822
PINK1 PTEN induced putative kinase 1 2.821
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 2.821
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.821
YTHDC1 YTH domain containing 1 2.821
FKBP5 FK506 binding protein 5 2.821
ZUP1 zinc finger containing ubiquitin peptidase 1 2.821
H2BC5 H2B clustered histone 5 2.821
ADCY10 adenylate cyclase 10 (soluble) 2.82
BACE1 beta-site APP-cleaving enzyme 1 2.82
IL2RA interleukin 2 receptor, alpha 2.819
CDK7 cyclin-dependent kinase 7 2.819
H2BC1 H2B clustered histone 1 2.819
NCOA1 nuclear receptor coactivator 1 2.818
FURIN furin (paired basic amino acid cleaving enzyme) 2.818
VEGFC vascular endothelial growth factor C 2.817
DLL4 delta-like 4 (Drosophila) 2.817
IL9 interleukin 9 2.817
TCF7 transcription factor 7 (T-cell specific, HMG-box) 2.816
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.816
IFNA4 interferon, alpha 4 2.816
RCOR1 REST corepressor 1 2.815
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 2.815
CD2 CD2 molecule 2.813
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.813
H2BC11 H2B clustered histone 11 2.813
CHD7 chromodomain helicase DNA binding protein 7 2.811
WTAP Wilms tumor 1 associated protein 2.811
NKRF NFKB repressing factor 2.81
DLL1 delta-like 1 (Drosophila) 2.809
CDC25A cell division cycle 25A 2.807
H2BC12 H2B clustered histone 12 2.807
NFYA nuclear transcription factor Y, alpha 2.806
EMD emerin 2.806
PTBP1 polypyrimidine tract binding protein 1 2.806
CHD4 chromodomain helicase DNA binding protein 4 2.806
H2BC3 H2B clustered histone 3 2.806
CD1C CD1c molecule 2.805
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 2.805
PDPN podoplanin 2.804
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.804
XDH xanthine dehydrogenase 2.804
COX4I1 cytochrome c oxidase subunit IV isoform 1 2.804
COPS5 COP9 signalosome subunit 5 2.803
H2BC15 H2B clustered histone 15 2.803
ARRB2 arrestin, beta 2 2.802
ICOS inducible T-cell co-stimulator 2.802
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.802
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.802
H2BC17 H2B clustered histone 17 2.802
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 2.801
CDC6 cell division cycle 6 2.801
H2BC9 H2B clustered histone 9 2.801
H2BC26 H2B clustered histone 26 2.801
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 2.799
CDC25C cell division cycle 25C 2.799
BARD1 BRCA1 associated RING domain 1 2.799
CD99 CD99 molecule 2.799
CDK5 cyclin-dependent kinase 5 2.799
TLR6 toll-like receptor 6 2.799
RABIF RAB interacting factor 2.798
TSLP thymic stromal lymphopoietin 2.798
BATF basic leucine zipper transcription factor, ATF-like 2.798
H2BC14 H2B clustered histone 14 2.798
H2BW1 H2B.W histone 1 2.798
CD9 CD9 molecule 2.797
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.797
C3 complement component 3 2.797
H2BC13 H2B clustered histone 13 2.797
H2BW2 H2B.W histone 2 2.797
H2BC12L H2B clustered histone 12 like 2.797
H2BC18 H2B clustered histone 18 2.797
HSPA1B heat shock 70kDa protein 1B 2.796
SMAD5 SMAD family member 5 2.796
CLEC7A C-type lectin domain family 7, member A 2.796
PLEK pleckstrin 2.796
KMT2C lysine (K)-specific methyltransferase 2C 2.795
PAX3 paired box 3 2.795
PTTG1 pituitary tumor-transforming 1 2.795
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 2.794
H2BK1 H2B.K variant histone 1 2.794
RBX1 ring-box 1, E3 ubiquitin protein ligase 2.793
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 2.793
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.792
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 2.791
MEN1 multiple endocrine neoplasia I 2.791
MT1E metallothionein 1E 2.791
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 2.791
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.791
TFE3 transcription factor binding to IGHM enhancer 3 2.791
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 2.791
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 2.79
MAML1 mastermind-like 1 (Drosophila) 2.789
IL17F interleukin 17F 2.789
PLAT plasminogen activator, tissue 2.788
MKI67 marker of proliferation Ki-67 2.788
IRS2 insulin receptor substrate 2 2.788
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 2.787
PBRM1 polybromo 1 2.787
STAT4 signal transducer and activator of transcription 4 2.787
PXDN peroxidasin 2.786
GUSB glucuronidase, beta 2.786
LTF lactotransferrin 2.786
CDC45 cell division cycle 45 2.785
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 2.784
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.784
OGG1 8-oxoguanine DNA glycosylase 2.784
RBBP4 retinoblastoma binding protein 4 2.784
ASCL1 achaete-scute family bHLH transcription factor 1 2.783
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 2.783
IFNA13 interferon, alpha 13 2.783
CTBP1 C-terminal binding protein 1 2.782
CCL22 chemokine (C-C motif) ligand 22 2.781
TIMP2 TIMP metallopeptidase inhibitor 2 2.78
MLKL mixed lineage kinase domain-like 2.78
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 2.779
PLEK2 pleckstrin 2 2.779
HBEGF heparin-binding EGF-like growth factor 2.778
MAP2K4 mitogen-activated protein kinase kinase 4 2.778
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 2.777
SMAD6 SMAD family member 6 2.777
RPTOR regulatory associated protein of MTOR, complex 1 2.777
FGF21 fibroblast growth factor 21 2.777
IDO2 indoleamine 2,3-dioxygenase 2 2.777
TYR tyrosinase 2.776
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.776
NOX1 NADPH oxidase 1 2.775
PRMT1 protein arginine methyltransferase 1 2.775
PLCG1 phospholipase C, gamma 1 2.775
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.774
PTHLH parathyroid hormone-like hormone 2.773
IFNA5 interferon, alpha 5 2.773
WNT4 wingless-type MMTV integration site family, member 4 2.772
S100A4 S100 calcium binding protein A4 2.772
SETDB1 SET domain, bifurcated 1 2.772
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.772
RRM2 ribonucleotide reductase M2 2.771
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.771
DDB1 damage-specific DNA binding protein 1, 127kDa 2.771
CSNK1A1 casein kinase 1, alpha 1 2.77
HNF1B HNF1 homeobox B 2.77
FBXO32 F-box protein 32 2.769
GSTP1 glutathione S-transferase pi 1 2.769
PML promyelocytic leukemia 2.769
IFNA8 interferon, alpha 8 2.769
KLF5 Kruppel-like factor 5 (intestinal) 2.768
MBNL1 muscleblind-like splicing regulator 1 2.768
IFNA6 interferon, alpha 6 2.767
RANBP2 RAN binding protein 2 2.767
IFNA14 interferon, alpha 14 2.767
TRAT1 T cell receptor associated transmembrane adaptor 1 2.766
PABPC1 poly(A) binding protein, cytoplasmic 1 2.766