OA-10-AB96_0.1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=0.1uM, (2S)-4-methyl-2-[[4-phenyl-2-(sulfanylmethyl)butanoyl]amino]pentanamide, Collagenase Inhibitors targeting MMP11, MMP14, MMP15, MMP16, MMP17, MMP19, MMP23A, MMP20, MMP27, MMP28, MMP21 (Novartis, 146680956)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/146680956
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Genes

8 genes differentially expressed following the OA-10-AB96_0.1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
RPS18 ribosomal protein S18 0.474314
UBE2C ubiquitin-conjugating enzyme E2C 0.282102
TMEM258 transmembrane protein 258 0.258424
NCAPD2 non-SMC condensin I complex, subunit D2 0.221994
RPL18A ribosomal protein L18a 0.213616
SPATC1L spermatogenesis and centriole associated 1-like 0.213616
RHOG ras homolog family member G 0.213616
ZNF740 zinc finger protein 740 0.20902