OA-10-AB96_1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=1uM, (2S)-4-methyl-2-[[4-phenyl-2-(sulfanylmethyl)butanoyl]amino]pentanamide, Collagenase Inhibitors targeting MMP11, MMP14, MMP15, MMP16, MMP17, MMP19, MMP23A, MMP20, MMP27, MMP28, MMP21 (Novartis, 146680956)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/146680956
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Genes

4 genes differentially expressed following the OA-10-AB96_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.252907
NEFH neurofilament, heavy polypeptide 0.242781
RPS18 ribosomal protein S18 0.242781

decreased expression

Symbol Name Standardized Value
EHD1 EH-domain containing 1 -0.252907