OA-10-PB21_1uM Gene Set

Dataset	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category	transcriptomics
Type	drug perturbation
Description	Dose=1uM, Tiospirone, alpha1-Adrenoceptor Antagonists targeting ADRA1B, HTR1E, HTR1F (Novartis, 55752)
External Link	https://pubchem.ncbi.nlm.nih.gov/compound/55752
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Genes

7 genes differentially expressed following the OA-10-PB21_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol	Name	Standardized Value

decreased expression

Symbol	Name	Standardized Value
PPDPF	pancreatic progenitor cell differentiation and proliferation factor	-0.684338
RXYLT1	ribitol xylosyltransferase 1	-0.66555
RPL11	ribosomal protein L11	-0.510128
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	-0.466716
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	-0.450812
SF3B6	splicing factor 3b, subunit 6, 14kDa	-0.433845
LRRC37B	leucine rich repeat containing 37B	-0.37276