OA-74-FH10_0.1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=0.1uM, Losartan Carboxaldehyde, Cyclooxygenase-2 Inhibitors;Angiotensin AT1 Antagonists targeting AGTR1, PTGS2 (Novartis, 9802264)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/9802264
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Genes

20 genes differentially expressed following the OA-74-FH10_0.1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
RPS9 ribosomal protein S9 0.626172
CIAO2B cytosolic iron-sulfur assembly component 2B 0.25912
LGALS1 lectin, galactoside-binding, soluble, 1 0.25912
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 0.25912
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.253566
RPLP2 ribosomal protein, large, P2 0.241377
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.233942
ENAM enamelin 0.233942
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 0.233942
BLVRB biliverdin reductase B 0.233942
TMEM258 transmembrane protein 258 0.217185
DHPS deoxyhypusine synthase 0.214416
CENPM centromere protein M 0.214416
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.207671
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.206677
RPLP1 ribosomal protein, large, P1 0.205159
TLN2 talin 2 0.205159
RPS14 ribosomal protein S14 0.205159
CDC20 cell division cycle 20 0.203035
RPS26 ribosomal protein S26 0.202016