OA-74-FH10_10uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=10uM, Losartan Carboxaldehyde, Cyclooxygenase-2 Inhibitors;Angiotensin AT1 Antagonists targeting AGTR1, PTGS2 (Novartis, 9802264)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/9802264
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Genes

11 genes differentially expressed following the OA-74-FH10_10uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
FKBP1A FK506 binding protein 1A, 12kDa 1.49218
RPLP2 ribosomal protein, large, P2 0.55196
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.245594
PRRX2 paired related homeobox 2 0.245594
ABHD14B abhydrolase domain containing 14B 0.244187
RPS9 ribosomal protein S9 0.230902
RPL5 ribosomal protein L5 0.209277
RPS21 ribosomal protein S21 0.202009

decreased expression

Symbol Name Standardized Value
CLSTN1 calsyntenin 1 -0.520297
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.494119
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) -0.202009