OB-46-IM27_1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=1uM, N-[2-[[3-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]ethyl]acetamide (Novartis, 24986839)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/24986839
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Genes

6 genes differentially expressed following the OB-46-IM27_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
BLVRB biliverdin reductase B 1.61486
MVP major vault protein 0.683437
LGALS1 lectin, galactoside-binding, soluble, 1 0.309407
DCAF7 DDB1 and CUL4 associated factor 7 0.304868
FBXW5 F-box and WD repeat domain containing 5 0.304868

decreased expression

Symbol Name Standardized Value
TMEM59 transmembrane protein 59 -0.277993