OB-65-AI50_0.01uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=0.01uM, Rgfp966, HDAC3 active-site competitive inhibitor;HDAC3 targeting HDAC3 (Novartis, 56650312)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/56650312
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Genes

7 genes differentially expressed following the OB-65-AI50_0.01uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
PPDPF pancreatic progenitor cell differentiation and proliferation factor 1.49501
PGP phosphoglycolate phosphatase 0.77669
RACK1 receptor for activated C kinase 1 0.545668
RPL31 ribosomal protein L31 0.244319

decreased expression

Symbol Name Standardized Value
DLG5 discs, large homolog 5 (Drosophila) -0.749695
ZNF3 zinc finger protein 3 -0.48735
SEC31A SEC31 homolog A (S. cerevisiae) -0.259802