OB-65-AI50_1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=1uM, Rgfp966, HDAC3 active-site competitive inhibitor;HDAC3 targeting HDAC3 (Novartis, 56650312)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/56650312
Similar Terms
Downloads & Tools

Genes

5 genes differentially expressed following the OB-65-AI50_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
TRIM16 tripartite motif containing 16 0.417764
FTL ferritin, light polypeptide 0.252463
HMOX1 heme oxygenase 1 0.240872

decreased expression

Symbol Name Standardized Value
HES6 hes family bHLH transcription factor 6 -0.379287
DCTN3 dynactin 3 (p22) -0.244637