OB-83-EA66_10uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=10uM, (S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amino]-3-[4-(2,6-dichloro-benzyloxy)-phenyl]-propionic acid, Cell Adhesion Inhibitors;Integrin alpha4beta1 (VLA-4) Antagonists targeting ITGB1 (Novartis, 9870468)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/9870468
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Genes

9 genes differentially expressed following the OB-83-EA66_10uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
RPS16 ribosomal protein S16 0.762097
CRYAB crystallin, alpha B 0.591558
RPL28 ribosomal protein L28 0.394743
HDAC5 histone deacetylase 5 0.33216
MVP major vault protein 0.310739
KRT18 keratin 18, type I 0.303919
RPS11 ribosomal protein S11 0.292649
KRTAP3-1 keratin associated protein 3-1 0.216152

decreased expression

Symbol Name Standardized Value
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -0.250907