OCRL Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description oculocerebrorenal syndrome of Lowe|This gene encodes a phosphatase enzyme that is involved in actin polymerization and is found in the trans-Golgi network. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4952)
External Link https://ncbi.nlm.nih.gov/gene/4952
Similar Terms
Downloads & Tools

Genes

498 genes differentially expressed following the OCRL gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAL mal, T-cell differentiation protein 0.0174611
ZDHHC6 zinc finger, DHHC-type containing 6 0.014907
NREP neuronal regeneration related protein 0.0133493
CD200 CD200 molecule 0.0128857
EVI2A ecotropic viral integration site 2A 0.0124043
EAPP E2F-associated phosphoprotein 0.0121541
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.0119445
MAGEA3 melanoma antigen family A3 0.0113656
CXCL12 chemokine (C-X-C motif) ligand 12 0.0112983
ATP5F1C ATP synthase F1 subunit gamma 0.0112451
MAT2B methionine adenosyltransferase II, beta 0.0112218
CSTA cystatin A (stefin A) 0.0110596
SELL selectin L 0.0109847
CEMIP cell migration inducing protein, hyaluronan binding 0.010889
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.010776
WFDC2 WAP four-disulfide core domain 2 0.0107301
WDR61 WD repeat domain 61 0.0105593
MRPL19 mitochondrial ribosomal protein L19 0.0105442
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0104563
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.0104436
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.0102861
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.0101679
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.0100565
CETN2 centrin, EF-hand protein, 2 0.00977975
LTF lactotransferrin 0.00975862
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00972332
PHYH phytanoyl-CoA 2-hydroxylase 0.00971906
PITX3 paired-like homeodomain 3 0.00970951
MDFIC MyoD family inhibitor domain containing 0.00955053
LY96 lymphocyte antigen 96 0.0094861
GCA grancalcin, EF-hand calcium binding protein 0.00947225
DOK5 docking protein 5 0.00945579
CRIP1 cysteine-rich protein 1 (intestinal) 0.0094547
AK4 adenylate kinase 4 0.00943344
RGS4 regulator of G-protein signaling 4 0.00940874
FDX1 ferredoxin 1 0.009389
LY6D lymphocyte antigen 6 complex, locus D 0.00923908
RGS10 regulator of G-protein signaling 10 0.00919775
NUSAP1 nucleolar and spindle associated protein 1 0.00906977
CDC42 cell division cycle 42 0.00901559
OXA1L oxidase (cytochrome c) assembly 1-like 0.00898801
MED28 mediator complex subunit 28 0.00898365
ELAVL1 ELAV like RNA binding protein 1 0.00897714
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.0089662
SET SET nuclear proto-oncogene 0.00894978
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00893921
EXOC5 exocyst complex component 5 0.00890856
CXCL8 chemokine (C-X-C motif) ligand 8 0.00889914
PLP1 proteolipid protein 1 0.00887757
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00885556
DAZAP2 DAZ associated protein 2 0.00884307
NDN necdin, melanoma antigen (MAGE) family member 0.00879338
TP53I3 tumor protein p53 inducible protein 3 0.00878745
NEBL nebulette 0.00877806
ISG20 interferon stimulated exonuclease gene 20kDa 0.00875268
PRKCA protein kinase C, alpha 0.00874375
ANG angiogenin, ribonuclease, RNase A family, 5 0.00872137
ESD esterase D 0.00871597
DEFB1 defensin, beta 1 0.00871002
GUCY2C guanylate cyclase 2C 0.0087056
CFI complement factor I 0.00865357
PEX2 peroxisomal biogenesis factor 2 0.00863959
COMMD10 COMM domain containing 10 0.00859913
S100A10 S100 calcium binding protein A10 0.00856754
MAGEA12 melanoma antigen family A12 0.00855976
HOXB7 homeobox B7 0.00847885
IL2RG interleukin 2 receptor, gamma 0.00843225
CLDND1 claudin domain containing 1 0.00842882
CD59 CD59 molecule, complement regulatory protein 0.00842315
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.0084168
NRN1 neuritin 1 0.00839244
IFT52 intraflagellar transport 52 0.00838702
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00835523
GDI2 GDP dissociation inhibitor 2 0.00834968
SELENOT selenoprotein T 0.00819281
PGAM1 phosphoglycerate mutase 1 (brain) 0.00819194
FABP7 fatty acid binding protein 7, brain 0.0081892
C1QBP complement component 1, q subcomponent binding protein 0.00816517
CGRRF1 cell growth regulator with ring finger domain 1 0.00815673
THBS2 thrombospondin 2 0.00810282
ANXA1 annexin A1 0.00807384
GSTO1 glutathione S-transferase omega 1 0.00806915
OLFM4 olfactomedin 4 0.00803682
TLR4 toll-like receptor 4 0.00803092
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00802909
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 0.00800411
ADD3 adducin 3 (gamma) 0.00800001
MAMLD1 mastermind-like domain containing 1 0.00795958
ARHGAP15 Rho GTPase activating protein 15 0.00794458
NUP37 nucleoporin 37kDa 0.00793426
IL1R2 interleukin 1 receptor, type II 0.00789957
MT1X metallothionein 1X 0.007881
ATRAID all-trans retinoic acid-induced differentiation factor 0.00785881
KIAA0226L KIAA0226-like 0.00785852
PLPBP pyridoxal phosphate binding protein 0.00785307
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00782426
RCAN1 regulator of calcineurin 1 0.00781864
NIPSNAP1 nipsnap homolog 1 (C. elegans) 0.00779545
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 0.00775484
FAR2 fatty acyl CoA reductase 2 0.0077352
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 0.0077228
RMDN1 regulator of microtubule dynamics 1 0.00770776
LTA4H leukotriene A4 hydrolase 0.00769589
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00766726
CEL carboxyl ester lipase 0.00764605
HAUS4 HAUS augmin-like complex, subunit 4 0.00764116
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00761569
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00761111
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00760849
POSTN periostin, osteoblast specific factor 0.00758109
RPA3 replication protein A3, 14kDa 0.0075771
MICA MHC class I polypeptide-related sequence A 0.00757018
RNF14 ring finger protein 14 0.00756148
OLFML3 olfactomedin-like 3 0.00752944
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00752473
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00750162
LRRN3 leucine rich repeat neuronal 3 0.00747135
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00747064
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.00744205
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00743277
YIPF5 Yip1 domain family, member 5 0.00742764
MMD monocyte to macrophage differentiation-associated 0.00741481
TSPAN6 tetraspanin 6 0.00738525
BMP4 bone morphogenetic protein 4 0.0073809
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.00737709
INHBA inhibin, beta A 0.00737489
UGP2 UDP-glucose pyrophosphorylase 2 0.00737267
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00736825
IGFBP5 insulin-like growth factor binding protein 5 0.00735721
GEMIN2 gem (nuclear organelle) associated protein 2 0.00734663
MOCS2 molybdenum cofactor synthesis 2 0.00733344
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 0.00732018
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.00730527
ICAM3 intercellular adhesion molecule 3 0.0072487
TPM4 tropomyosin 4 0.00723862
CD9 CD9 molecule 0.00722998
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 0.00722954
KRT19 keratin 19, type I 0.0072258
AURKB aurora kinase B 0.00722198
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00720982
S100A7 S100 calcium binding protein A7 0.00719303
DCK deoxycytidine kinase 0.00717955
LGALS13 lectin, galactoside-binding, soluble, 13 0.00717088
BCL2A1 BCL2-related protein A1 0.00716725
DMAC2L distal membrane arm assembly component 2 like 0.00715502
FAM198B family with sequence similarity 198, member B 0.00715279
SKP1 S-phase kinase-associated protein 1 0.00715216
TREM1 triggering receptor expressed on myeloid cells 1 0.00714322
GPN1 GPN-loop GTPase 1 0.00713751
TACSTD2 tumor-associated calcium signal transducer 2 0.00712495
SLC35A5 solute carrier family 35, member A5 0.00711386
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00710981
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00710815
PDE4B phosphodiesterase 4B, cAMP-specific 0.00709567
DUOX2 dual oxidase 2 0.00709141
GLOD4 glyoxalase domain containing 4 0.00707864
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00707222
C3ORF14 chromosome 3 open reading frame 14 0.00703059
RSL24D1 ribosomal L24 domain containing 1 0.00702583
RPA2 replication protein A2, 32kDa 0.00700088
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.00700088
ACSS3 acyl-CoA synthetase short-chain family member 3 0.00696495
RIOX2 ribosomal oxygenase 2 0.00695458
KRCC1 lysine-rich coiled-coil 1 0.0069429
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00693152
GTPBP8 GTP-binding protein 8 (putative) 0.00692383
SRSF1 serine/arginine-rich splicing factor 1 0.00689064
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00687063
STON1 stonin 1 0.00684087
MOXD1 monooxygenase, DBH-like 1 0.00681467
MKKS McKusick-Kaufman syndrome 0.00681075
REEP5 receptor accessory protein 5 0.00677545
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00677495
CDC123 cell division cycle 123 0.00677109
SSR1 signal sequence receptor, alpha 0.00677029
SDF2 stromal cell-derived factor 2 0.00676857
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.0067619
ZFAND1 zinc finger, AN1-type domain 1 0.00674987
OXSM 3-oxoacyl-ACP synthase, mitochondrial 0.00674223
H1-0 H1.0 linker histone 0.00674129
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00671518
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.00671114
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.00671107
CD48 CD48 molecule 0.00670666
SCAMP1 secretory carrier membrane protein 1 0.00670167
SINHCAF SIN3-HDAC complex associated factor 0.00669644
GPR65 G protein-coupled receptor 65 0.00667808
WASHC4 WASH complex subunit 4 0.00667583
CCNA2 cyclin A2 0.00666889
ATG5 autophagy related 5 0.00666567
TMEM230 transmembrane protein 230 0.00665374
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00665241
ANO10 anoctamin 10 0.00663785
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.00663351
MMP8 matrix metallopeptidase 8 0.00663229
SNX11 sorting nexin 11 0.0066317
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00662494
DCXR dicarbonyl/L-xylulose reductase 0.00661927
PRDX3 peroxiredoxin 3 0.00660881
ADGRE1 adhesion G protein-coupled receptor E1 0.00657245
S100B S100 calcium binding protein B 0.00656284
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00656229
CYB5R4 cytochrome b5 reductase 4 0.0065615
ARL3 ADP-ribosylation factor-like 3 0.00652746
IQCG IQ motif containing G 0.00651783
C5ORF30 chromosome 5 open reading frame 30 0.00650818
NDP Norrie disease (pseudoglioma) 0.00650712
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00650262
TCEAL2 transcription elongation factor A (SII)-like 2 0.00648657
SULF1 sulfatase 1 0.00646698
PITX1 paired-like homeodomain 1 0.00646173
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00645786
VDAC2 voltage-dependent anion channel 2 0.0064505
ACAT2 acetyl-CoA acetyltransferase 2 0.00644117
GLIPR1 GLI pathogenesis-related 1 0.00643897
RHOB ras homolog family member B 0.00643453
TMEM14B transmembrane protein 14B 0.00643366
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.00643087
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00641883
ADRA2A adrenoceptor alpha 2A 0.0064145
CCNG1 cyclin G1 0.00640315
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.00639933
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00639752
RHOH ras homolog family member H 0.00638096
MRPL39 mitochondrial ribosomal protein L39 0.00637325
MT1E metallothionein 1E 0.00636548
TPD52L1 tumor protein D52-like 1 0.00635611
CYTIP cytohesin 1 interacting protein 0.00635282
PHB2 prohibitin 2 0.0063513
MRPL40 mitochondrial ribosomal protein L40 0.00634968
VSNL1 visinin-like 1 0.00634548
ALB albumin 0.00633883
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00633857
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00633662
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.00632596
JPT1 Jupiter microtubule associated homolog 1 0.00632416
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00631801
CLTB clathrin, light chain B 0.00631139
TMEM38B transmembrane protein 38B 0.006306
CTSZ cathepsin Z 0.00630401
LINC00623 long intergenic non-protein coding RNA 623 0.00630238
PLS3 plastin 3 0.00630106
GARS1 glycyl-tRNA synthetase 1 0.00629406
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00629108
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00628376
GYPC glycophorin C (Gerbich blood group) 0.00628226
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00628148
ZNF232 zinc finger protein 232 0.00628129
FAM162A family with sequence similarity 162, member A 0.00626973

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0212723
MAP7 microtubule-associated protein 7 -0.0131981
MGLL monoglyceride lipase -0.0123257
SYNGR3 synaptogyrin 3 -0.0122662
PTK2 protein tyrosine kinase 2 -0.0121819
NOTCH2NL notch 2 N-terminal like -0.0120964
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0118705
BASP1 brain abundant, membrane attached signal protein 1 -0.0115245
ADCY9 adenylate cyclase 9 -0.0115149
MTCL1 microtubule crosslinking factor 1 -0.0113944
RGS5 regulator of G-protein signaling 5 -0.0112506
TPSAB1 tryptase alpha/beta 1 -0.0110864
TSPAN12 tetraspanin 12 -0.0110751
APOD apolipoprotein D -0.0110196
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.0110127
TGM2 transglutaminase 2 -0.0110034
AKAP8 A kinase (PRKA) anchor protein 8 -0.0109782
PROM1 prominin 1 -0.0108687
SIK1 salt-inducible kinase 1 -0.0108653
FTH1 ferritin, heavy polypeptide 1 -0.0107864
NEFH neurofilament, heavy polypeptide -0.01066
CFB complement factor B -0.0105899
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.0103755
AQP1 aquaporin 1 (Colton blood group) -0.0100934
PLD3 phospholipase D family, member 3 -0.00993314
REEP1 receptor accessory protein 1 -0.00991427
WDR7 WD repeat domain 7 -0.00989395
SMC1A structural maintenance of chromosomes 1A -0.00982351
TOX3 TOX high mobility group box family member 3 -0.00977774
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00973748
DYNLL1 dynein, light chain, LC8-type 1 -0.00969492
KANK1 KN motif and ankyrin repeat domains 1 -0.00968842
CLU clusterin -0.00956157
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.00952862
LY6E lymphocyte antigen 6 complex, locus E -0.00951616
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.009507
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00949364
AGR2 anterior gradient 2 -0.00935389
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00934487
TNS3 tensin 3 -0.009334
PPL periplakin -0.00925862
BAD BCL2-associated agonist of cell death -0.00924813
SIDT2 SID1 transmembrane family, member 2 -0.00923911
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.00916451
TRIO trio Rho guanine nucleotide exchange factor -0.00911744
DOCK9 dedicator of cytokinesis 9 -0.00911128
RET ret proto-oncogene -0.00906829
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00906196
DUSP5 dual specificity phosphatase 5 -0.0089857
STK39 serine threonine kinase 39 -0.00898433
LAMA5 laminin, alpha 5 -0.00894917
MET MET proto-oncogene, receptor tyrosine kinase -0.00893325
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00892231
IFI6 interferon, alpha-inducible protein 6 -0.00891119
DUSP6 dual specificity phosphatase 6 -0.00888402
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.0088689
TSPAN13 tetraspanin 13 -0.0087875
VWF von Willebrand factor -0.00878728
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00877515
ASRGL1 asparaginase like 1 -0.0087704
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00863038
MMP1 matrix metallopeptidase 1 -0.00862667
FBLN2 fibulin 2 -0.00862169
AKR1C1 aldo-keto reductase family 1, member C1 -0.00861452
ACADVL acyl-CoA dehydrogenase, very long chain -0.0086112
KLHDC10 kelch domain containing 10 -0.00860022
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.00856212
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.0085565
HSPA1A heat shock 70kDa protein 1A -0.00853608
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00851107
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00848105
SUGP2 SURP and G patch domain containing 2 -0.00847736
PTCH1 patched 1 -0.00846632
STEAP3 STEAP family member 3, metalloreductase -0.00845287
IRS2 insulin receptor substrate 2 -0.0084271
AGRN agrin -0.00839319
PLXNA1 plexin A1 -0.00832719
DGKZ diacylglycerol kinase, zeta -0.00829803
SCGB1D2 secretoglobin, family 1D, member 2 -0.00824034
COL15A1 collagen, type XV, alpha 1 -0.00819859
SCGB2A1 secretoglobin, family 2A, member 1 -0.008184
AHR aryl hydrocarbon receptor -0.00816638
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -0.00805078
HSPB8 heat shock 22kDa protein 8 -0.00805004
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00803702
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.0080051
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00799281
CCL5 chemokine (C-C motif) ligand 5 -0.00795208
C3 complement component 3 -0.00791954
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00791557
NXN nucleoredoxin -0.00791087
PRKCZ protein kinase C, zeta -0.00789836
SPARCL1 SPARC-like 1 (hevin) -0.00783564
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.00776922
C4BPA complement component 4 binding protein, alpha -0.0077539
UPK1B uroplakin 1B -0.00775217
CREBBP CREB binding protein -0.007705
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00770163
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.00767349
PRSS8 protease, serine, 8 -0.00765407
FABP4 fatty acid binding protein 4, adipocyte -0.00765239
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00764787
ELAC2 elaC ribonuclease Z 2 -0.00763538
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00762801
PLXNB2 plexin B2 -0.00760429
SPON2 spondin 2, extracellular matrix protein -0.00760174
GUSB glucuronidase, beta -0.00759756
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00758144
KANK2 KN motif and ankyrin repeat domains 2 -0.00757142
PCDH17 protocadherin 17 -0.00756769
FOXD1 forkhead box D1 -0.00756481
TGFBI transforming growth factor, beta-induced, 68kDa -0.00755319
PRRC2C proline-rich coiled-coil 2C -0.00755019
TRIM14 tripartite motif containing 14 -0.00754946
PDE10A phosphodiesterase 10A -0.00752242
STK25 serine/threonine kinase 25 -0.00751709
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00751028
CTBP1 C-terminal binding protein 1 -0.00750923
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00750801
TTC39A tetratricopeptide repeat domain 39A -0.00750549
FKBP11 FK506 binding protein 11, 19 kDa -0.00748967
PLXNA2 plexin A2 -0.00748392
AKR1C2 aldo-keto reductase family 1, member C2 -0.0074813
AHNAK2 AHNAK nucleoprotein 2 -0.00746185
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00744852
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -0.00742913
XK X-linked Kx blood group -0.00742106
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00741697
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00741343
MITF microphthalmia-associated transcription factor -0.00740319
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00739514
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00739278
NUAK1 NUAK family, SNF1-like kinase, 1 -0.00739171
IDO1 indoleamine 2,3-dioxygenase 1 -0.00738611
JMJD1C jumonji domain containing 1C -0.00737835
BRD4 bromodomain containing 4 -0.00737699
HAUS3 HAUS augmin-like complex, subunit 3 -0.00737585
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00737046
ZBTB20 zinc finger and BTB domain containing 20 -0.00734706
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00734209
DPP4 dipeptidyl-peptidase 4 -0.00734022
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00732685
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00731783
LTBP2 latent transforming growth factor beta binding protein 2 -0.00731544
ZBTB7A zinc finger and BTB domain containing 7A -0.00729647
DST dystonin -0.00728363
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.0072727
PLXND1 plexin D1 -0.00725877
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00725335
KCTD12 potassium channel tetramerization domain containing 12 -0.00724812
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00722452
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.00720901
EML3 echinoderm microtubule associated protein like 3 -0.00716018
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00715856
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00715094
FBXW12 F-box and WD repeat domain containing 12 -0.00715026
EHBP1L1 EH domain binding protein 1-like 1 -0.00713962
GGTLC1 gamma-glutamyltransferase light chain 1 -0.00712776
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00710049
RBBP6 retinoblastoma binding protein 6 -0.00704357
CD320 CD320 molecule -0.00703321
RND3 Rho family GTPase 3 -0.00702923
LAMB1 laminin, beta 1 -0.00702818
STXBP2 syntaxin binding protein 2 -0.00701813
ADGRF5 adhesion G protein-coupled receptor F5 -0.00700475
KIAA0930 KIAA0930 -0.0069992
FOXJ3 forkhead box J3 -0.00699801
SRPK1 SRSF protein kinase 1 -0.00699619
SCRIB scribbled planar cell polarity protein -0.00699572
FGFR3 fibroblast growth factor receptor 3 -0.00699029
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -0.00698494
FAM13A family with sequence similarity 13, member A -0.00696414
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00695478
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00694808
RAPSN receptor-associated protein of the synapse -0.00694783
PHACTR2 phosphatase and actin regulator 2 -0.0069404
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00693634
NOTCH1 notch 1 -0.00691459
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00689282
RTN2 reticulon 2 -0.00687993
TLE2 transducin-like enhancer of split 2 -0.00687601
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00686538
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00686385
TUFT1 tuftelin 1 -0.00685748
MELK maternal embryonic leucine zipper kinase -0.00684222
DVL1 dishevelled segment polarity protein 1 -0.00681879
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00680163
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00679794
MICALL2 MICAL-like 2 -0.00678122
ZNF512B zinc finger protein 512B -0.00676708
SPRY4 sprouty homolog 4 (Drosophila) -0.00674961
NRIP3 nuclear receptor interacting protein 3 -0.0067415
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 -0.0067335
RCOR1 REST corepressor 1 -0.0067333
OFD1 oral-facial-digital syndrome 1 -0.00673274
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00672596
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.00672079
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00672006
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00671731
COG7 component of oligomeric golgi complex 7 -0.0066984
OTUD4 OTU deubiquitinase 4 -0.00668722
EHD3 EH-domain containing 3 -0.00665834
CPA3 carboxypeptidase A3 (mast cell) -0.00663351
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00663252
KLC1 kinesin light chain 1 -0.00663135
PRKD2 protein kinase D2 -0.00662961
NPY1R neuropeptide Y receptor Y1 -0.00661756
DCLK1 doublecortin-like kinase 1 -0.00661745
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.00660126
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.00659073
VARS valyl-tRNA synthetase -0.00658371
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.00656931
MYO6 myosin VI -0.00656015
DPT dermatopontin -0.0065557
TMEM41B transmembrane protein 41B -0.00654886
ZCCHC2 zinc finger, CCHC domain containing 2 -0.00653327
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00653181
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.0065227
CUX1 cut-like homeobox 1 -0.00652068
HOPX HOP homeobox -0.00651148
DROSHA drosha, ribonuclease type III -0.00650842
DUSP7 dual specificity phosphatase 7 -0.00650305
CSNK1G2 casein kinase 1, gamma 2 -0.00650259
PILRB paired immunoglobin-like type 2 receptor beta -0.00650119
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -0.00648974
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.00648661
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.00647388
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.00646576
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.00645908
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00644108
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00643954
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00642821
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00642711
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00642046
LAMP1 lysosomal-associated membrane protein 1 -0.00641033
TMEM259 transmembrane protein 259 -0.0063989
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -0.00639825
PDGFD platelet derived growth factor D -0.00638582
CTSD cathepsin D -0.0063794
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00636452
MYO10 myosin X -0.00635162
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.00635108
IGF2R insulin-like growth factor 2 receptor -0.00634471
TSPAN9 tetraspanin 9 -0.0063389
RBM26 RNA binding motif protein 26 -0.00632313
RNPS1 RNA binding protein S1, serine-rich domain -0.00632108
PXDC1 PX domain containing 1 -0.00630675
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F -0.00630588
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.0063038