OE-04-VO07_0.1uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=0.1uM, 2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)-5-((2-(methylsulfinyl)pyridin-3-yl)methyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole, Calcium-Sensing Receptor (CaSR) Antagonists targeting CASR (Novartis, 24753707)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/24753707
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Genes

10 genes differentially expressed following the OE-04-VO07_0.1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
RPL8 ribosomal protein L8 0.900375
APRT adenine phosphoribosyltransferase 0.900375
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.800276
CST3 cystatin C 0.518747
UBC ubiquitin C 0.447894
LDHB lactate dehydrogenase B 0.447894
RPS27 ribosomal protein S27 0.358427
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.226957
RPL36 ribosomal protein L36 0.226957
CRYAB crystallin, alpha B 0.221712