OE-04-VO07_1uM Gene Set

Dataset	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category	transcriptomics
Type	drug perturbation
Description	Dose=1uM, 2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)-5-((2-(methylsulfinyl)pyridin-3-yl)methyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole, Calcium-Sensing Receptor (CaSR) Antagonists targeting CASR (Novartis, 24753707)
External Link	https://pubchem.ncbi.nlm.nih.gov/compound/24753707
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Genes

10 genes differentially expressed following the OE-04-VO07_1uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol	Name	Standardized Value
APRT	adenine phosphoribosyltransferase	0.713257
RPS27	ribosomal protein S27	0.59076
UBA52	ubiquitin A-52 residue ribosomal protein fusion product 1	0.458548
LDHB	lactate dehydrogenase B	0.388773
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.311025
UBC	ubiquitin C	0.253985
C19ORF33	chromosome 19 open reading frame 33	0.253985
IFI27L2	interferon, alpha-inducible protein 27-like 2	0.225873
ELOB	elongin B	0.209251

decreased expression

Symbol	Name	Standardized Value
SNX3	sorting nexin 3	-0.222599