OE-50-VB46_0.01uM Gene Set

Dataset NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category transcriptomics
Type drug perturbation
Description Dose=0.01uM, 4-hydroxy7-(1-hydroxy-2-{2-[4-(4-phenyl-butoxy)-phenyl]-ethylamino}-ethyl)-3H-benzothiazol-2-one, beta2-Adrenoceptor Agonists targeting ADRB2 (Novartis, 9805095)
External Link https://pubchem.ncbi.nlm.nih.gov/compound/9805095
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Genes

6 genes differentially expressed following the OE-50-VB46_0.01uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol Name Standardized Value
FKBP1A FK506 binding protein 1A, 12kDa 1.16359
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.350555
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.311583
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.296369

decreased expression

Symbol Name Standardized Value
MICU1 mitochondrial calcium uptake 1 -0.570066
LRRC8A leucine rich repeat containing 8 family, member A -0.296369