OF-28-PH15_10uM Gene Set

Dataset	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles
Category	transcriptomics
Type	drug perturbation
Description	Dose=10uM, 4-(3-tert-Butylamino-2-hydroxypropoxy)benzimidazol-2-one, beta3-Adrenoceptor Agonists targeting ADRB3 (Novartis, 2687)
External Link	https://pubchem.ncbi.nlm.nih.gov/compound/2687
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Genes

8 genes differentially expressed following the OF-28-PH15_10uM drug perturbation from the NIBR DRUG-seq U2OS MoA Box dataset.

increased expression

Symbol	Name	Standardized Value
RPS9	ribosomal protein S9	1.16181
COX7C	cytochrome c oxidase subunit VIIc	0.844057

decreased expression

Symbol	Name	Standardized Value
SMPDL3B	sphingomyelin phosphodiesterase, acid-like 3B	-0.280405
SLC25A4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	-0.253172
HMX2	H6 family homeobox 2	-0.211566
ARCN1	archain 1	-0.200197
SPG7	spastic paraplegia 7 (pure and complicated autosomal recessive)	-0.200197
USP3	ubiquitin specific peptidase 3	-0.200197