| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)|This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 4967) |
| External Link | https://ncbi.nlm.nih.gov/gene/4967 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the OGDH gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ISG15 | ISG15 ubiquitin-like modifier | 0.0154748 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0123442 |
| MAGEA3 | melanoma antigen family A3 | 0.0118872 |
| MX1 | MX dynamin-like GTPase 1 | 0.00971023 |
| IRF7 | interferon regulatory factor 7 | 0.00943243 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00872379 |
| MAGEA12 | melanoma antigen family A12 | 0.00834379 |
| AK4 | adenylate kinase 4 | 0.00820994 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00796307 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00789755 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00789146 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00772088 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00755032 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00734306 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00706618 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00696484 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00689255 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00681857 |
| TAGLN | transgelin | 0.0068128 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00681186 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00678921 |
| ADM | adrenomedullin | 0.00678906 |
| COG7 | component of oligomeric golgi complex 7 | 0.00667704 |
| MYBPC1 | myosin binding protein C, slow type | 0.00667072 |
| HMOX1 | heme oxygenase 1 | 0.00662243 |
| PITX3 | paired-like homeodomain 3 | 0.00660641 |
| MT1E | metallothionein 1E | 0.00657549 |
| MT1X | metallothionein 1X | 0.00646811 |
| CRYAB | crystallin, alpha B | 0.00644409 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00631783 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0062927 |
| FSCN1 | fascin actin-bundling protein 1 | 0.00628896 |
| ATF3 | activating transcription factor 3 | 0.00623889 |
| CCN2 | cellular communication network factor 2 | 0.00612079 |
| CBS | cystathionine-beta-synthase | 0.00609408 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00607356 |
| PLXNB2 | plexin B2 | 0.0060578 |
| TRAF4 | TNF receptor-associated factor 4 | 0.0060202 |
| XAF1 | XIAP associated factor 1 | 0.00599456 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00595704 |
| LCN2 | lipocalin 2 | 0.0059363 |
| GRN | granulin | 0.00591449 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00587772 |
| IFI44L | interferon-induced protein 44-like | 0.00585875 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00584841 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00574978 |
| IFI44 | interferon-induced protein 44 | 0.00573346 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00573032 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00572541 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00572155 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00569887 |
| C3 | complement component 3 | 0.00565297 |
| MT1G | metallothionein 1G | 0.00563317 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00559488 |
| PIP | prolactin-induced protein | 0.00559246 |
| RNASET2 | ribonuclease T2 | 0.00556055 |
| PROM1 | prominin 1 | 0.0055269 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00552564 |
| MX2 | MX dynamin-like GTPase 2 | 0.00552539 |
| MAGEA1 | melanoma antigen family A1 | 0.00551189 |
| CD70 | CD70 molecule | 0.00548912 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00548481 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00546609 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00540993 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00540871 |
| H1-2 | H1.2 linker histone, cluster member | 0.00540026 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00536882 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00533359 |
| CRIP2 | cysteine-rich protein 2 | 0.0052886 |
| METRN | meteorin, glial cell differentiation regulator | 0.00526731 |
| FLNA | filamin A, alpha | 0.0052551 |
| PFKL | phosphofructokinase, liver | 0.00522505 |
| SPEN | spen family transcriptional repressor | 0.00520412 |
| GPM6B | glycoprotein M6B | 0.00518015 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00514843 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00514818 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00514122 |
| RHOB | ras homolog family member B | 0.00513855 |
| PALLD | palladin, cytoskeletal associated protein | 0.00512387 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00509724 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00509655 |
| ZNF91 | zinc finger protein 91 | 0.00509148 |
| EVL | Enah/Vasp-like | 0.00507136 |
| MMP3 | matrix metallopeptidase 3 | 0.00505968 |
| TUBB6 | tubulin, beta 6 class V | 0.00505343 |
| BIN1 | bridging integrator 1 | 0.00504192 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00501354 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00500523 |
| VPREB1 | pre-B lymphocyte 1 | 0.0049892 |
| ACKR3 | atypical chemokine receptor 3 | 0.00497924 |
| HOMER1 | homer scaffolding protein 1 | 0.00497348 |
| TNNC1 | troponin C type 1 (slow) | 0.00496138 |
| KRT15 | keratin 15, type I | 0.00495608 |
| RCAN1 | regulator of calcineurin 1 | 0.00492656 |
| TRIM29 | tripartite motif containing 29 | 0.00492083 |
| IL1B | interleukin 1, beta | 0.00492026 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.00489112 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00488829 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00487185 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00486456 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00485885 |
| IFI35 | interferon-induced protein 35 | 0.00485818 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00485754 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00485701 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.00482421 |
| MT1F | metallothionein 1F | 0.00481423 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0047937 |
| INHBA | inhibin, beta A | 0.00478335 |
| MME | membrane metallo-endopeptidase | 0.00476878 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00476552 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00474105 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00473634 |
| TRIM22 | tripartite motif containing 22 | 0.00473305 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00471278 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.00471121 |
| SASH1 | SAM and SH3 domain containing 1 | 0.00470397 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00466559 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00464902 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00463444 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.00462846 |
| DENND5A | DENN/MADD domain containing 5A | 0.00461569 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0046109 |
| AK1 | adenylate kinase 1 | 0.00460281 |
| MT1H | metallothionein 1H | 0.00459374 |
| ECM1 | extracellular matrix protein 1 | 0.00459083 |
| OXTR | oxytocin receptor | 0.00458765 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | 0.00456278 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00454565 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0045432 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00453948 |
| IL32 | interleukin 32 | 0.00453188 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00453007 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00452521 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0044981 |
| AHNAK | AHNAK nucleoprotein | 0.00449052 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.00448733 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00448294 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00445992 |
| TMEM47 | transmembrane protein 47 | 0.00443949 |
| LIF | leukemia inhibitory factor | 0.00441766 |
| CCNF | cyclin F | 0.00441241 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00438896 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 0.00437916 |
| JMJD6 | jumonji domain containing 6 | 0.0043784 |
| TMEM131L | transmembrane 131 like | 0.00436841 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00435631 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00433898 |
| RRAGA | Ras-related GTP binding A | 0.00432472 |
| VEGFA | vascular endothelial growth factor A | 0.00432162 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00432127 |
| DSP | desmoplakin | 0.00430475 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00430444 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00430042 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00429683 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.004292 |
| RRAD | Ras-related associated with diabetes | 0.00428729 |
| ENO1 | enolase 1, (alpha) | 0.00428652 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0042833 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00427165 |
| DES | desmin | 0.00426558 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.00426407 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00426347 |
| FERMT2 | fermitin family member 2 | 0.00425383 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00424328 |
| KRT7 | keratin 7, type II | 0.00423612 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00423095 |
| STC2 | stanniocalcin 2 | 0.00422917 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00420932 |
| SYNGR3 | synaptogyrin 3 | 0.0042088 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00420751 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.00420501 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.00420373 |
| MYL9 | myosin, light chain 9, regulatory | 0.00419164 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00418576 |
| CORO1C | coronin, actin binding protein, 1C | 0.00418562 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00418205 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.00416594 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.00416538 |
| ASS1 | argininosuccinate synthase 1 | 0.00415285 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00414357 |
| KLF9 | Kruppel-like factor 9 | 0.00413594 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.0041266 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00412625 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00412166 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00409841 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00409544 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00409084 |
| GAB2 | GRB2-associated binding protein 2 | 0.0040868 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00408659 |
| CDK14 | cyclin-dependent kinase 14 | 0.00407308 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00406853 |
| POR | P450 (cytochrome) oxidoreductase | 0.0040635 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00405373 |
| LOX | lysyl oxidase | 0.0040526 |
| KLK11 | kallikrein-related peptidase 11 | 0.00404655 |
| KLF6 | Kruppel-like factor 6 | 0.00404601 |
| TTN | titin | 0.00404482 |
| USP18 | ubiquitin specific peptidase 18 | 0.00404197 |
| FBN1 | fibrillin 1 | 0.00404051 |
| ABHD2 | abhydrolase domain containing 2 | 0.00403315 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00402354 |
| LHFP | lipoma HMGIC fusion partner | 0.00401203 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00400815 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00399349 |
| RHOC | ras homolog family member C | 0.00399348 |
| AHSG | alpha-2-HS-glycoprotein | 0.0039716 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00396708 |
| S100A7 | S100 calcium binding protein A7 | 0.00396417 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | 0.00396408 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00395151 |
| FCGBP | Fc fragment of IgG binding protein | 0.0039503 |
| NRCAM | neuronal cell adhesion molecule | 0.00394505 |
| PLVAP | plasmalemma vesicle associated protein | 0.00393837 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 0.00393541 |
| ZNF589 | zinc finger protein 589 | 0.003918 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | 0.00391659 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00391358 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00390725 |
| ABAT | 4-aminobutyrate aminotransferase | 0.0039012 |
| KLF10 | Kruppel-like factor 10 | 0.00389231 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00389176 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.0038875 |
| RTN2 | reticulon 2 | 0.00388671 |
| APOB | apolipoprotein B | 0.00387364 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.00387166 |
| PLK3 | polo-like kinase 3 | 0.00386991 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0038668 |
| PER1 | period circadian clock 1 | 0.00386653 |
| MRC2 | mannose receptor, C type 2 | 0.00385478 |
| SP110 | SP110 nuclear body protein | 0.00385073 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.0038419 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00384108 |
| REG1A | regenerating islet-derived 1 alpha | 0.00383996 |
| VCAN | versican | 0.00383894 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00383256 |
| ENO3 | enolase 3 (beta, muscle) | 0.00382499 |
| NOTCH1 | notch 1 | 0.00381895 |
| PLLP | plasmolipin | 0.00380493 |
| KRT18 | keratin 18, type I | 0.00380313 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00380183 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00379641 |
| DMD | dystrophin | 0.00379166 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | 0.00378966 |
| RHOF | ras homolog family member F (in filopodia) | 0.00378347 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.00376858 |
| TPM2 | tropomyosin 2 (beta) | 0.00375623 |
| AGRN | agrin | 0.00375405 |
| GYS1 | glycogen synthase 1 (muscle) | 0.00374663 |
| DEFB1 | defensin, beta 1 | 0.00373986 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | -0.00970675 |
| MAP7 | microtubule-associated protein 7 | -0.00876805 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00843542 |
| CCDC92 | coiled-coil domain containing 92 | -0.00785872 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00759657 |
| PCP4 | Purkinje cell protein 4 | -0.00747571 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00731069 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00718666 |
| BEX1 | brain expressed, X-linked 1 | -0.00700588 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00677609 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00671903 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00671877 |
| MATN2 | matrilin 2 | -0.0066145 |
| LYZ | lysozyme | -0.00641227 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00640997 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00633934 |
| DACH1 | dachshund family transcription factor 1 | -0.00623134 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00610375 |
| ZW10 | zw10 kinetochore protein | -0.00599917 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00597183 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00596369 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00594715 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.0058122 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00579954 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00573872 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0056564 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00564717 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00563174 |
| MPZL2 | myelin protein zero-like 2 | -0.00561872 |
| ITGA6 | integrin, alpha 6 | -0.00560915 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.00560114 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00558165 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00546352 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00541242 |
| ORC1 | origin recognition complex, subunit 1 | -0.00537008 |
| COMMD10 | COMM domain containing 10 | -0.0053675 |
| LXN | latexin | -0.00534208 |
| REEP1 | receptor accessory protein 1 | -0.00534108 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00530399 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00530075 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00525598 |
| TMEM255A | transmembrane protein 255A | -0.0052217 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.00520625 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00519379 |
| FRZB | frizzled-related protein | -0.00517351 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00516241 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00515042 |
| TMEM176B | transmembrane protein 176B | -0.00513978 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00510374 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00507973 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00505037 |
| CLDND1 | claudin domain containing 1 | -0.00498016 |
| OLFM1 | olfactomedin 1 | -0.00495822 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00495485 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00495102 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -0.00492459 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.0049211 |
| DENND2D | DENN/MADD domain containing 2D | -0.00490351 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.0048849 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00487103 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.0048564 |
| RGS13 | regulator of G-protein signaling 13 | -0.004835 |
| NVL | nuclear VCP-like | -0.00480886 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00475156 |
| INSM1 | insulinoma-associated 1 | -0.00473974 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00472397 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00472286 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00471689 |
| PON3 | paraoxonase 3 | -0.00468644 |
| SFTPC | surfactant protein C | -0.00467195 |
| TFEC | transcription factor EC | -0.00466385 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00466133 |
| RWDD1 | RWD domain containing 1 | -0.00464816 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00464506 |
| MED21 | mediator complex subunit 21 | -0.0046389 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00463265 |
| RCAN2 | regulator of calcineurin 2 | -0.00462196 |
| FEM1B | fem-1 homolog b (C. elegans) | -0.00461431 |
| FBXO21 | F-box protein 21 | -0.0045888 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00457968 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00457598 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00457573 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00456778 |
| TSPAN6 | tetraspanin 6 | -0.00454585 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00448611 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00448212 |
| TESC | tescalcin | -0.00447666 |
| SFTPB | surfactant protein B | -0.00447603 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00446182 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -0.004459 |
| WBP5 | WW domain binding protein 5 | -0.00445825 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00444654 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00442648 |
| MGP | matrix Gla protein | -0.00442282 |
| CTSH | cathepsin H | -0.00442168 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00440782 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00440248 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00439545 |
| EXPH5 | exophilin 5 | -0.00439436 |
| GLCE | glucuronic acid epimerase | -0.00439252 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00437387 |
| AGR2 | anterior gradient 2 | -0.00436481 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00435581 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00435455 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00435296 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.00434584 |
| RNF130 | ring finger protein 130 | -0.00434566 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00434114 |
| TMSB15A | thymosin beta 15a | -0.00432591 |
| PRDX2 | peroxiredoxin 2 | -0.00432243 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00432019 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00431475 |
| CHN2 | chimerin 2 | -0.00431352 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00430858 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00428723 |
| GNAS | GNAS complex locus | -0.00428709 |
| TAC1 | tachykinin, precursor 1 | -0.00427904 |
| FOXF1 | forkhead box F1 | -0.00425963 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00425895 |
| FBXO5 | F-box protein 5 | -0.00424903 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00424095 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00422531 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | -0.00421991 |
| PLXNC1 | plexin C1 | -0.00421381 |
| KLHL9 | kelch-like family member 9 | -0.00420933 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00420794 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00420684 |
| THAP12 | THAP domain containing 12 | -0.00420215 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00419674 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00419417 |
| EPCAM | epithelial cell adhesion molecule | -0.0041836 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00417817 |
| PBK | PDZ binding kinase | -0.00416106 |
| SLC16A4 | solute carrier family 16, member 4 | -0.00414068 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.00412732 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.00411352 |
| CRTAP | cartilage associated protein | -0.00410566 |
| CD1E | CD1e molecule | -0.0040929 |
| DCLK1 | doublecortin-like kinase 1 | -0.00408296 |
| CD63 | CD63 molecule | -0.00407699 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00407471 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00406451 |
| CST1 | cystatin SN | -0.00405406 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00404269 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00402573 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00401946 |
| RAB32 | RAB32, member RAS oncogene family | -0.00401546 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00400729 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | -0.00399384 |
| PMP22 | peripheral myelin protein 22 | -0.00398275 |
| SFTPA2 | surfactant protein A2 | -0.00397669 |
| ING3 | inhibitor of growth family, member 3 | -0.00396401 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00395083 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | -0.00393651 |
| SFTPD | surfactant protein D | -0.00392622 |
| CTBP2 | C-terminal binding protein 2 | -0.00392366 |
| ATP5ME | ATP synthase membrane subunit e | -0.00391087 |
| KIF5B | kinesin family member 5B | -0.00389944 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00388397 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00387397 |
| GPER1 | G protein-coupled estrogen receptor 1 | -0.00387221 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00387219 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00386187 |
| IL18 | interleukin 18 | -0.0038457 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00383739 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00383401 |
| GTF2I | general transcription factor IIi | -0.00383286 |
| PDGFD | platelet derived growth factor D | -0.00383156 |
| VDAC3 | voltage-dependent anion channel 3 | -0.0038302 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | -0.00381238 |
| STMN1 | stathmin 1 | -0.00379944 |
| DBF4 | DBF4 zinc finger | -0.00379749 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.00379045 |
| EXOC5 | exocyst complex component 5 | -0.00378412 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | -0.00377412 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | -0.00376831 |
| PEX7 | peroxisomal biogenesis factor 7 | -0.00376807 |
| SRP9 | signal recognition particle 9kDa | -0.00376459 |
| MEST | mesoderm specific transcript | -0.00376238 |
| TRAM1 | translocation associated membrane protein 1 | -0.00376094 |
| DCK | deoxycytidine kinase | -0.00375798 |
| ENSA | endosulfine alpha | -0.00375695 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00375188 |
| THAP10 | THAP domain containing 10 | -0.00375097 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00374629 |
| CANX | calnexin | -0.00374316 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00373021 |
| CD8A | CD8a molecule | -0.00371741 |
| ISL1 | ISL LIM homeobox 1 | -0.00370785 |
| KRCC1 | lysine-rich coiled-coil 1 | -0.00370026 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00369492 |
| PRTN3 | proteinase 3 | -0.00367622 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0036744 |
| BMP6 | bone morphogenetic protein 6 | -0.00366884 |
| RBBP7 | retinoblastoma binding protein 7 | -0.00366249 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00365692 |
| TXN | thioredoxin | -0.00365125 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00361479 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00360925 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00360041 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00359918 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.00359594 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00359329 |
| CD163 | CD163 molecule | -0.0035866 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00358524 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | -0.00358263 |
| CHMP3 | charged multivesicular body protein 3 | -0.00358223 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0035754 |
| ESR1 | estrogen receptor 1 | -0.00357409 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00357187 |
| MRPS14 | mitochondrial ribosomal protein S14 | -0.00357056 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00356999 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 | -0.00356801 |
| CREBZF | CREB/ATF bZIP transcription factor | -0.00356463 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.00355827 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0035566 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00355296 |
| CCNB2 | cyclin B2 | -0.00354976 |
| SLC38A6 | solute carrier family 38, member 6 | -0.0035474 |
| GPR88 | G protein-coupled receptor 88 | -0.00353345 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0035291 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -0.00352399 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00352376 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00352065 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 | -0.00351229 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.00350665 |
| IFT57 | intraflagellar transport 57 | -0.00350191 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00349484 |
| NTS | neurotensin | -0.00348213 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.0034798 |
| TSPYL1 | TSPY-like 1 | -0.00346555 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00345569 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00344782 |
| ABHD10 | abhydrolase domain containing 10 | -0.00344407 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00344288 |
| TPRKB | TP53RK binding protein | -0.00343479 |
| MALL | mal, T-cell differentiation protein-like | -0.00343436 |
| ELANE | elastase, neutrophil expressed | -0.00343384 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.00343194 |
| EZR | ezrin | -0.00343185 |
| VIM | vimentin | -0.00342841 |
| LUM | lumican | -0.00342483 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.003413 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00340703 |
| RDX | radixin | -0.00340645 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.00340367 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00339262 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | -0.00337602 |
| MCM9 | minichromosome maintenance complex component 9 | -0.00337575 |
