OPM-2 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Plasma Cell Myeloma Tumour (Cell Model Passports, SIDM00457)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00457
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Genes

199 proteins associated with the cell line OPM-2 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AGK acylglycerol kinase
AK5 adenylate kinase 5
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
APLF aprataxin and PNKP like factor
APRT adenine phosphoribosyltransferase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP13A1 ATPase type 13A1
BAK1 BCL2-antagonist/killer 1
CAB39L calcium binding protein 39-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CDON cell adhesion associated, oncogene regulated
CISD2 CDGSH iron sulfur domain 2
CLPTM1L CLPTM1-like
CREG1 cellular repressor of E1A-stimulated genes 1
CTHRC1 collagen triple helix repeat containing 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
CUL1 cullin 1
DCPS decapping enzyme, scavenger
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DESI1 desumoylating isopeptidase 1
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DUSP12 dual specificity phosphatase 12
EDC4 enhancer of mRNA decapping 4
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EHBP1L1 EH domain binding protein 1-like 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
F5 coagulation factor V (proaccelerin, labile factor)
FDPS farnesyl diphosphate synthase
FERMT1 fermitin family member 1
FLAD1 flavin adenine dinucleotide synthetase 1
FMNL1 formin-like 1
GALM galactose mutarotase (aldose 1-epimerase)
GMEB1 glucocorticoid modulatory element binding protein 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GSTO1 glutathione S-transferase omega 1
HADH hydroxyacyl-CoA dehydrogenase
HAGH hydroxyacylglutathione hydrolase
HBS1L HBS1-like translational GTPase
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HPRT1 hypoxanthine phosphoribosyltransferase 1
IRF2BPL interferon regulatory factor 2 binding protein-like
ITGB7 integrin, beta 7
ITM2C integral membrane protein 2C
LIG3 ligase III, DNA, ATP-dependent
LIME1 Lck interacting transmembrane adaptor 1
LOC102724603 uncharacterized LOC102724603
LONP2 lon peptidase 2, peroxisomal
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MEA1 male-enhanced antigen 1
MEF2C myocyte enhancer factor 2C
MEF2D myocyte enhancer factor 2D
METTL7A methyltransferase like 7A
MTA2 metastasis associated 1 family, member 2
NME3 NME/NM23 nucleoside diphosphate kinase 3
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
PAAF1 proteasomal ATPase-associated factor 1
PABPC3 poly(A) binding protein, cytoplasmic 3
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PARP1 poly (ADP-ribose) polymerase 1
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PM20D2 peptidase M20 domain containing 2
PMVK phosphomevalonate kinase
PPOX protoporphyrinogen oxidase
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PRKD2 protein kinase D2
SCARB2 scavenger receptor class B, member 2
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B4 splicing factor 3b, subunit 4, 49kDa
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SNX18 sorting nexin 18
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SRCIN1 SRC kinase signaling inhibitor 1
STBD1 starch binding domain 1
STIM1 stromal interaction molecule 1
SUB1 SUB1 homolog (S. cerevisiae)
TECPR2 tectonin beta-propeller repeat containing 2
TIPRL TOR signaling pathway regulator
TMX2 thioredoxin-related transmembrane protein 2
TOP2B topoisomerase (DNA) II beta 180kDa
TRAM1 translocation associated membrane protein 1
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UCK2 uridine-cytidine kinase 2
UFC1 ubiquitin-fold modifier conjugating enzyme 1
USO1 USO1 vesicle transport factor
USP29 ubiquitin specific peptidase 29
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
ANAPC16 anaphase promoting complex subunit 16
APOOL apolipoprotein O-like
APP amyloid beta (A4) precursor protein
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ASPH aspartate beta-hydroxylase
BCL7A B-cell CLL/lymphoma 7A
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
C1ORF52 chromosome 1 open reading frame 52
CACUL1 CDK2-associated, cullin domain 1
CBR1 carbonyl reductase 1
CD99L2 CD99 molecule-like 2
CIC capicua transcriptional repressor
CLCC1 chloride channel CLIC-like 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNTRL centriolin
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae)
CORO1B coronin, actin binding protein, 1B
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTTN cortactin
DOCK7 dedicator of cytokinesis 7
ELOF1 elongation factor 1 homolog (S. cerevisiae)
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETFB electron-transfer-flavoprotein, beta polypeptide
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM207A family with sequence similarity 207, member A
FBXL20 F-box and leucine-rich repeat protein 20
FKRP fukutin related protein
FLNA filamin A, alpha
FYTTD1 forty-two-three domain containing 1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GFAP glial fibrillary acidic protein
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GSE1 Gse1 coiled-coil protein
HEATR5B HEAT repeat containing 5B
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HMG20A high mobility group 20A
IQCA1 IQ motif containing with AAA domain 1
IRS2 insulin receptor substrate 2
ITSN1 intersectin 1 (SH3 domain protein)
KDSR 3-ketodihydrosphingosine reductase
KIF18B kinesin family member 18B
LIMA1 LIM domain and actin binding 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRC37A5P leucine rich repeat containing 37, member A5, pseudogene
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MED24 mediator complex subunit 24
METTL15 methyltransferase like 15
MOB4 MOB family member 4, phocein
MRPL20 mitochondrial ribosomal protein L20
MRPS16 mitochondrial ribosomal protein S16
MRPS21 mitochondrial ribosomal protein S21
MRPS23 mitochondrial ribosomal protein S23
MRPS6 mitochondrial ribosomal protein S6
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NLN neurolysin (metallopeptidase M3 family)
NYAP1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
OGDHL oxoglutarate dehydrogenase-like
PCYOX1 prenylcysteine oxidase 1
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PHF3 PHD finger protein 3
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLXNB2 plexin B2
PNPLA6 patatin-like phospholipase domain containing 6
POGLUT1 protein O-glucosyltransferase 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PON2 paraoxonase 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
RFTN1 raftlin, lipid raft linker 1
RHPN2 rhophilin, Rho GTPase binding protein 2
RNA5SP422 RNA, 5S ribosomal pseudogene 422
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SFXN3 sideroflexin 3
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SMYD5 SMYD family member 5
SOAT1 sterol O-acyltransferase 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPIN1 spindlin 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STXBP3 syntaxin binding protein 3
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TJP2 tight junction protein 2
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TOR1AIP2 torsin A interacting protein 2
TRIM33 tripartite motif containing 33
TRMT5 tRNA methyltransferase 5
TUBB2A tubulin, beta 2A class IIa
VAT1 vesicle amine transport 1
WDR3 WD repeat domain 3
WDR46 WD repeat domain 46
ZC3H14 zinc finger CCCH-type containing 14
ZC3H8 zinc finger CCCH-type containing 8
ZNF185 zinc finger protein 185 (LIM domain)