OPM2 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
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Genes

542 gene knockdowns changing fitness of OPM2 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
SCARF1 scavenger receptor class F, member 1 3.18385
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.95983
EFNB2 ephrin-B2 2.82858
DHRS4L2 dehydrogenase/reductase (SDR family) member 4 like 2 2.61213
BPGM 2,3-bisphosphoglycerate mutase 2.5601
ECE1 endothelin converting enzyme 1 2.49373
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.39677
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.38985
HCCS holocytochrome c synthase 2.30511
COPA coatomer protein complex, subunit alpha 2.28176
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 2.27091
KNG1 kininogen 1 2.24045
RRM2 ribonucleotide reductase M2 2.23349
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.22199
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.20761
SSTR1 somatostatin receptor 1 2.17802
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.15738
GNS glucosamine (N-acetyl)-6-sulfatase 2.15512
HOMER2 homer scaffolding protein 2 2.13344
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 2.09974
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.09243
CRX cone-rod homeobox 2.08861
ENAM enamelin 2.04362
GPN3 GPN-loop GTPase 3 2.03794
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 2.03713
DHRS4L1 dehydrogenase/reductase (SDR family) member 4 like 1 2.0332
FOXL1 forkhead box L1 2.01499
SSTR2 somatostatin receptor 2 1.99589
JAG2 jagged 2 1.99329
ANXA7 annexin A7 1.98711
HMGN1 high mobility group nucleosome binding domain 1 1.92939
HIPK4 homeodomain interacting protein kinase 4 1.90221
NFX1 nuclear transcription factor, X-box binding 1 1.88915
ZNF738 zinc finger protein 738 1.87545
ZNF688 zinc finger protein 688 1.87182
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 1.86963
CD109 CD109 molecule 1.86066
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 1.8571
ZNF440 zinc finger protein 440 1.84944
SF3B3 splicing factor 3b, subunit 3, 130kDa 1.82609
HIST3H2A histone cluster 3, H2a 1.81378
TCL1A T-cell leukemia/lymphoma 1A 1.81185
ADHFE1 alcohol dehydrogenase, iron containing, 1 1.81079
TAS1R1 taste receptor, type 1, member 1 1.80492
OAZ1 ornithine decarboxylase antizyme 1 1.80451
LOC652119 1.80349
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 1.79975
TUSC3 tumor suppressor candidate 3 1.7851
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 1.78314
NFE2L2 nuclear factor, erythroid 2-like 2 1.77537
SLCO1B7 solute carrier organic anion transporter family, member 1B7 (non-functional) 1.76764
DTX1 deltex 1, E3 ubiquitin ligase 1.76676
C4BPB complement component 4 binding protein, beta 1.74607
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.7345
CPM carboxypeptidase M 1.70832
CNGB1 cyclic nucleotide gated channel beta 1 1.7081
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) 1.70805
SRBD1 S1 RNA binding domain 1 1.70759
PNPLA8 patatin-like phospholipase domain containing 8 1.70625
PTAFR platelet-activating factor receptor 1.70418
SNRPA small nuclear ribonucleoprotein polypeptide A 1.69732
HOXD13 homeobox D13 1.69423
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.68355
CRY1 cryptochrome circadian clock 1 1.68227
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 1.67262
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 1.6673
RPS17 ribosomal protein S17 1.66664
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 1.65457
HIST1H2AB histone cluster 1, H2ab 1.63556
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 1.61833
SPI1 Spi-1 proto-oncogene 1.61816
HIST1H2AD histone cluster 1, H2ad 1.61614
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 1.61363
RBM8A RNA binding motif protein 8A 1.61241
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.58859
EN2 engrailed homeobox 2 1.58634
ALKBH7 alkB, alkylation repair homolog 7 (E. coli) 1.57719
RPS3A ribosomal protein S3A 1.57531
PLA2R1 phospholipase A2 receptor 1, 180kDa 1.57142
FOXE3 forkhead box E3 1.57072
TWISTNB TWIST neighbor 1.56961
PRTN3 proteinase 3 1.56855
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 1.56751
HIST1H3D histone cluster 1, H3d 1.56303
UBR1 ubiquitin protein ligase E3 component n-recognin 1 1.56211
ZNF780B zinc finger protein 780B 1.56054
MEF2C myocyte enhancer factor 2C 1.54442
HIST1H2AL histone cluster 1, H2al 1.54311
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 1.54081
MYO3A myosin IIIA 1.53582
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 1.53555
HIST2H2AC histone cluster 2, H2ac 1.53295
BAG2 BCL2-associated athanogene 2 1.53211
ZNF358 zinc finger protein 358 1.52744
C1ORF87 chromosome 1 open reading frame 87 1.52478
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 1.5166
NACA2 nascent polypeptide-associated complex alpha subunit 2 1.51537
AHR aryl hydrocarbon receptor 1.51455
RPS19 ribosomal protein S19 1.5096
LPAR2 lysophosphatidic acid receptor 2 1.50549
ABHD13 abhydrolase domain containing 13 1.49596
CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1 1.49466
PPP1R3A protein phosphatase 1, regulatory subunit 3A 1.49384
MSMO1 methylsterol monooxygenase 1 1.49353
RPTOR regulatory associated protein of MTOR, complex 1 1.47982
WNT7B wingless-type MMTV integration site family, member 7B 1.47432
GPX3 glutathione peroxidase 3 1.46641
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 1.46538
ABLIM1 actin binding LIM protein 1 1.4651
CHD9 chromodomain helicase DNA binding protein 9 1.46292
WBP11 WW domain binding protein 11 1.4556
HOXA4 homeobox A4 1.44358
KYNU kynureninase 1.43859
PRDM11 PR domain containing 11 1.43263
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 1.43263
PHACTR4 phosphatase and actin regulator 4 1.42702
INTS4P2 integrator complex subunit 4 pseudogene 2 1.42662
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 1.42331
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 1.42269
TMF1 TATA element modulatory factor 1 1.41489
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.40759
HIST1H2BD histone cluster 1, H2bd 1.40485
RUVBL2 RuvB-like AAA ATPase 2 1.40317
SF3A2 splicing factor 3a, subunit 2, 66kDa 1.40158
ATXN3 ataxin 3 1.3991
GCLM glutamate-cysteine ligase, modifier subunit 1.39888
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 1.39562
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 1.39388
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 1.37333
INTS4 integrator complex subunit 4 1.37317
OCRL oculocerebrorenal syndrome of Lowe 1.37256
RC3H2 ring finger and CCCH-type domains 2 1.36996
CRCP CGRP receptor component 1.36992
IGBP1 immunoglobulin (CD79A) binding protein 1 1.35969
TOP2A topoisomerase (DNA) II alpha 170kDa 1.35744
WT1 Wilms tumor 1 1.35371
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 1.35228
TRUB2 TruB pseudouridine (psi) synthase family member 2 1.34854
PDF peptide deformylase (mitochondrial) 1.34383
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.34199
POLN polymerase (DNA directed) nu 1.34147
TOM1 target of myb1 (chicken) 1.33706
HIST1H2AG histone cluster 1, H2ag 1.3309
SRSF1 serine/arginine-rich splicing factor 1 1.33013
NKX2-2 NK2 homeobox 2 1.32967
UBE2I ubiquitin-conjugating enzyme E2I 1.32849
SPRYD7 SPRY domain containing 7 1.3248
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 1.32271
CARS cysteinyl-tRNA synthetase 1.31841
OR10J1 olfactory receptor, family 10, subfamily J, member 1 1.31757
SAE1 SUMO1 activating enzyme subunit 1 1.31603
LPPR1 lipid phosphate phosphatase-related protein type 1 1.30226
TPM3 tropomyosin 3 1.30181
LTB lymphotoxin beta (TNF superfamily, member 3) 1.29593
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 1.29475
SLC14A2 solute carrier family 14 (urea transporter), member 2 1.29295
FAT4 FAT atypical cadherin 4 1.28713
CSAD cysteine sulfinic acid decarboxylase 1.2868
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 1.28562
OVCA2 ovarian tumor suppressor candidate 2 1.28196
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 1.28092
ATP5J2-PTCD1 ATP5J2-PTCD1 readthrough 1.27928
CABP4 calcium binding protein 4 1.27655
UROD uroporphyrinogen decarboxylase 1.27204
ZNF398 zinc finger protein 398 1.2712
U2AF2 U2 small nuclear RNA auxiliary factor 2 1.26379
POMC proopiomelanocortin 1.26193
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.26154
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 1.26076
GPSM1 G-protein signaling modulator 1 1.26054
IL17RB interleukin 17 receptor B 1.25663
SRRM2 serine/arginine repetitive matrix 2 1.2551
NOTCH1 notch 1 1.25451
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.25443
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.25443
HOXC11 homeobox C11 1.25385
RHOT1 ras homolog family member T1 1.24977
AKAP9 A kinase (PRKA) anchor protein 9 1.23656
CDC5L cell division cycle 5-like 1.2331
PPP1R7 protein phosphatase 1, regulatory subunit 7 1.23067
EIF5B eukaryotic translation initiation factor 5B 1.22801
CHEK1 checkpoint kinase 1 1.2244
SMAD5 SMAD family member 5 1.22065
ZSCAN4 zinc finger and SCAN domain containing 4 1.22064
BCCIP BRCA2 and CDKN1A interacting protein 1.21955
XPR1 xenotropic and polytropic retrovirus receptor 1 1.21673
MRC2 mannose receptor, C type 2 1.2159
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.2125
LIG3 ligase III, DNA, ATP-dependent 1.21184
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 1.21182
AHCTF1 AT hook containing transcription factor 1 1.20577
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 1.20193
ENAH enabled homolog (Drosophila) 1.19972
PAX8 paired box 8 1.19757
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 1.18773
CLEC4D C-type lectin domain family 4, member D 1.18752
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.18483
ADGRE2 adhesion G protein-coupled receptor E2 1.18438
NODAL nodal growth differentiation factor 1.18333
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 1.1833
STX17 syntaxin 17 1.18279
ZFYVE9 zinc finger, FYVE domain containing 9 1.17516
PCSK9 proprotein convertase subtilisin/kexin type 9 1.17335
TRIM54 tripartite motif containing 54 1.1727
CALN1 calneuron 1 1.16954
PQBP1 polyglutamine binding protein 1 1.16954
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 1.16761
POM121 POM121 transmembrane nucleoporin 1.16381
KLF13 Kruppel-like factor 13 1.15806
SRPK1 SRSF protein kinase 1 1.15719
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 1.155
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 1.14898
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 1.14887
TUBA1A tubulin, alpha 1a 1.1442
RHCE Rh blood group, CcEe antigens 1.14262
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 1.14252
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.13904
SP4 Sp4 transcription factor 1.1348
FOXD4L5 forkhead box D4-like 5 1.13098
CAPS2 calcyphosine 2 1.12984
GZMM granzyme M (lymphocyte met-ase 1) 1.12796
LAMP2 lysosomal-associated membrane protein 2 1.12533
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 1.12137
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1.12057
PHAX phosphorylated adaptor for RNA export 1.12021
RNF113A ring finger protein 113A 1.11945
KARS lysyl-tRNA synthetase 1.11865
POM121C POM121 transmembrane nucleoporin C 1.11831
EDF1 endothelial differentiation-related factor 1 1.11727
SCUBE3 signal peptide, CUB domain, EGF-like 3 1.11494
ANKRD49 ankyrin repeat domain 49 1.11492
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 1.11451
PHKG2 phosphorylase kinase, gamma 2 (testis) 1.11262
PITX3 paired-like homeodomain 3 1.1113
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 1.11082
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 1.11081
QKI QKI, KH domain containing, RNA binding 1.11032
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 1.10939
CPA1 carboxypeptidase A1 (pancreatic) 1.10871
ARF1 ADP-ribosylation factor 1 1.1073
GRM6 glutamate receptor, metabotropic 6 1.10679
KCMF1 potassium channel modulatory factor 1 1.10348
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.09991
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.09759
APAF1 apoptotic peptidase activating factor 1 1.09339
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.09131
LYRM7 LYR motif containing 7 1.0901
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.08542
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 1.08503
CHRM4 cholinergic receptor, muscarinic 4 1.0838
NME1-NME2 NME1-NME2 readthrough 1.08248
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.07904
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.07807
PRDM2 PR domain containing 2, with ZNF domain 1.07804
FXN frataxin 1.07408
ETNK1 ethanolamine kinase 1 1.07371
MNX1 motor neuron and pancreas homeobox 1 1.06954
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 1.06888
RHBDD3 rhomboid domain containing 3 1.06324
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 1.06075
ATOH7 atonal homolog 7 (Drosophila) 1.06012
SF3B2 splicing factor 3b, subunit 2, 145kDa 1.05861
ILK integrin-linked kinase 1.05722
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 1.05404
TCF4 transcription factor 4 1.05169
MYEF2 myelin expression factor 2 1.04504
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.04393
YME1L1 YME1-like 1 ATPase 1.04343
SNRPG small nuclear ribonucleoprotein polypeptide G 1.04227
PRSS55 protease, serine, 55 1.04195
ADRM1 adhesion regulating molecule 1 1.04182
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 1.03567
PLIN3 perilipin 3 1.03563
RND3 Rho family GTPase 3 1.03521
ZNF329 zinc finger protein 329 1.03364
IGBP1P1 immunoglobulin (CD79A) binding protein 1 pseudogene 1 1.0326
PTBP1 polypyrimidine tract binding protein 1 1.03224
DUX3 double homeobox 3 1.03212
FOXD4L4 forkhead box D4-like 4 1.03198
ARHGAP39 Rho GTPase activating protein 39 1.03043
WIF1 WNT inhibitory factor 1 1.03003
TRIP13 thyroid hormone receptor interactor 13 1.02951
SNAPIN SNAP-associated protein 1.02867
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.02861
SKI SKI proto-oncogene 1.02829
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 1.02758
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 1.02612
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 1.02584
TMOD1 tropomodulin 1 1.02304
CLDN8 claudin 8 1.02219
PPARD peroxisome proliferator-activated receptor delta 1.02073
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 1.017
TGFBR1 transforming growth factor, beta receptor 1 1.01406
RFC2 replication factor C (activator 1) 2, 40kDa 1.01402
AKAP8 A kinase (PRKA) anchor protein 8 1.01402
BEGAIN brain-enriched guanylate kinase-associated 1.01357
NUP160 nucleoporin 160kDa 1.01141
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1.01013
PGD phosphogluconate dehydrogenase 1.0068
RAX retina and anterior neural fold homeobox 1.00292
SCAF11 SR-related CTD-associated factor 11 1.00021

decreased fitness

Symbol Name Standardized Value
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -3.57663
ZNF560 zinc finger protein 560 -3.24692
FBLN1 fibulin 1 -3.20067
TCERG1L transcription elongation regulator 1-like -3.1993
MT3 metallothionein 3 -2.85654
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -2.68858
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -2.67775
ZNF568 zinc finger protein 568 -2.67534
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -2.52783
UGP2 UDP-glucose pyrophosphorylase 2 -2.41672
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -2.38344
ADPGK ADP-dependent glucokinase -2.35865
KIAA0195 KIAA0195 -2.2912
PTEN phosphatase and tensin homolog -2.27661
CES1 carboxylesterase 1 -2.27016
TMEM234 transmembrane protein 234 -2.26877
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -2.25545
ZNF234 zinc finger protein 234 -2.16527
DRG2 developmentally regulated GTP binding protein 2 -2.14084
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -2.1208
CLCA2 chloride channel accessory 2 -2.05386
EFCAB11 EF-hand calcium binding domain 11 -2.02679
RAB19 RAB19, member RAS oncogene family -2.01953
LMO7 LIM domain 7 -2.01757
DCP1A decapping mRNA 1A -2.01692
STARD8 StAR-related lipid transfer (START) domain containing 8 -1.98645
AFF1 AF4/FMR2 family, member 1 -1.97272
FN3K fructosamine 3 kinase -1.96745
CST11 cystatin 11 -1.95956
CLCA1 chloride channel accessory 1 -1.93805
DMRT3 doublesex and mab-3 related transcription factor 3 -1.89842
PRDM1 PR domain containing 1, with ZNF domain -1.8968
MMP19 matrix metallopeptidase 19 -1.88564
MGP matrix Gla protein -1.86783
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 -1.86014
ZIM2 zinc finger, imprinted 2 -1.85132
IMPG2 interphotoreceptor matrix proteoglycan 2 -1.85086
PCDH15 protocadherin-related 15 -1.83126
GCLC glutamate-cysteine ligase, catalytic subunit -1.79516
CCNT2 cyclin T2 -1.79432
GTF2A1L general transcription factor IIA, 1-like -1.79245
STRN4 striatin, calmodulin binding protein 4 -1.787
RLF rearranged L-myc fusion -1.78074
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -1.77637
EDAR ectodysplasin A receptor -1.76514
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -1.75716
ADK adenosine kinase -1.75511
DNASE2B deoxyribonuclease II beta -1.74506
SRPR signal recognition particle receptor (docking protein) -1.7446
LIMD1 LIM domains containing 1 -1.72206
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -1.70715
OR1N2 olfactory receptor, family 1, subfamily N, member 2 -1.68751
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -1.68369
MAP3K8 mitogen-activated protein kinase kinase kinase 8 -1.68287
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -1.6724
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -1.65071
TSC22D3 TSC22 domain family, member 3 -1.64828
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.64643
MXD4 MAX dimerization protein 4 -1.63855
CDA cytidine deaminase -1.6383
IRF4 interferon regulatory factor 4 -1.63522
BCAP29 B-cell receptor-associated protein 29 -1.63321
FAM131B family with sequence similarity 131, member B -1.63129
DNAI1 dynein, axonemal, intermediate chain 1 -1.61499
ONECUT1 one cut homeobox 1 -1.60491
LUC7L LUC7-like (S. cerevisiae) -1.59619
CCND2 cyclin D2 -1.57759
BRWD1 bromodomain and WD repeat domain containing 1 -1.57438
ZMYND11 zinc finger, MYND-type containing 11 -1.57188
FGF13 fibroblast growth factor 13 -1.5675
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 -1.55887
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -1.54551
TRIM6 tripartite motif containing 6 -1.54121
MEST mesoderm specific transcript -1.52572
TULP4 tubby like protein 4 -1.52129
DSG1 desmoglein 1 -1.51465
CCL25 chemokine (C-C motif) ligand 25 -1.49228
IL21 interleukin 21 -1.48623
ZNF566 zinc finger protein 566 -1.47187
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -1.46914
PPP1R3F protein phosphatase 1, regulatory subunit 3F -1.46194
AMY2B amylase, alpha 2B (pancreatic) -1.4486
IQGAP2 IQ motif containing GTPase activating protein 2 -1.44665
GPR83 G protein-coupled receptor 83 -1.44369
STK17B serine/threonine kinase 17b -1.44358
FXYD2 FXYD domain containing ion transport regulator 2 -1.44089
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -1.43983
MXI1 MAX interactor 1, dimerization protein -1.43654
ECH1 enoyl CoA hydratase 1, peroxisomal -1.43588
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -1.43474
ADAMTSL4 ADAMTS-like 4 -1.43079
CAB39 calcium binding protein 39 -1.42432
NLRP3 NLR family, pyrin domain containing 3 -1.4229
PDIK1L PDLIM1 interacting kinase 1 like -1.42119
CABP5 calcium binding protein 5 -1.41463
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -1.41315
CYP21A1P cytochrome P450, family 21, subfamily A, polypeptide 1 pseudogene -1.40408
ARF5 ADP-ribosylation factor 5 -1.39524
TGFA transforming growth factor, alpha -1.39203
PARP8 poly (ADP-ribose) polymerase family, member 8 -1.38622
RBM15 RNA binding motif protein 15 -1.38178
RNASE6 ribonuclease, RNase A family, k6 -1.38086
PAQR5 progestin and adipoQ receptor family member V -1.37456
ORM2 orosomucoid 2 -1.36652
CLCA4 chloride channel accessory 4 -1.366
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 -1.36468
RIMS3 regulating synaptic membrane exocytosis 3 -1.35526
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -1.3543
IFT20 intraflagellar transport 20 -1.34617
LY75-CD302 LY75-CD302 readthrough -1.3421
KCTD10 potassium channel tetramerization domain containing 10 -1.34088
NQO1 NAD(P)H dehydrogenase, quinone 1 -1.33896
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2 -1.33863
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -1.33564
NIN ninein (GSK3B interacting protein) -1.32961
INHBC inhibin, beta C -1.32933
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -1.32633
ZNF423 zinc finger protein 423 -1.32616
MMP28 matrix metallopeptidase 28 -1.32375
EOMES eomesodermin -1.31581
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 -1.30784
STON1-GTF2A1L STON1-GTF2A1L readthrough -1.30622
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 -1.30578
PARP10 poly (ADP-ribose) polymerase family, member 10 -1.30436
ZNF174 zinc finger protein 174 -1.3003
ADAR adenosine deaminase, RNA-specific -1.29922
OR2G2 olfactory receptor, family 2, subfamily G, member 2 -1.29609
NELL2 NEL-like 2 (chicken) -1.28254
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) -1.27349
MMP13 matrix metallopeptidase 13 -1.26649
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 -1.25854
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -1.25817
LTBP4 latent transforming growth factor beta binding protein 4 -1.25391
HSDL2 hydroxysteroid dehydrogenase like 2 -1.25094
NEIL2 nei endonuclease VIII-like 2 (E. coli) -1.24875
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -1.24797
DNM1P46 dynamin 1 pseudogene 46 -1.24501
RGS18 regulator of G-protein signaling 18 -1.24455
TPK1 thiamin pyrophosphokinase 1 -1.24213
MPO myeloperoxidase -1.2411
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 -1.2261
FBXO9 F-box protein 9 -1.22421
PPP4R1 protein phosphatase 4, regulatory subunit 1 -1.22084
PDLIM5 PDZ and LIM domain 5 -1.21596
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -1.21432
LGI1 leucine-rich, glioma inactivated 1 -1.20712
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.20094
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 -1.20087
NOS2 nitric oxide synthase 2, inducible -1.19591
SPINK1 serine peptidase inhibitor, Kazal type 1 -1.19585
PDE4DIP phosphodiesterase 4D interacting protein -1.19538
PNLIPRP1 pancreatic lipase-related protein 1 -1.19255
ZNF211 zinc finger protein 211 -1.19146
RFX2 regulatory factor X, 2 (influences HLA class II expression) -1.19022
HOXC5 homeobox C5 -1.1898
EYS eyes shut homolog (Drosophila) -1.18513
OGFR opioid growth factor receptor -1.17943
TRIP6 thyroid hormone receptor interactor 6 -1.17231
CTTN cortactin -1.17032
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 -1.1685
PLSCR3 phospholipid scramblase 3 -1.16739
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -1.16291
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -1.15735
UBQLN1 ubiquilin 1 -1.1557
KDR kinase insert domain receptor -1.15488
DDHD2 DDHD domain containing 2 -1.15485
PRDX6 peroxiredoxin 6 -1.1518
OTUD7A OTU deubiquitinase 7A -1.15087
CTSH cathepsin H -1.15064
OR1E1 olfactory receptor, family 1, subfamily E, member 1 -1.14963
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -1.14887
GRK5 G protein-coupled receptor kinase 5 -1.14518
KDM3B lysine (K)-specific demethylase 3B -1.14499
IKZF2 IKAROS family zinc finger 2 (Helios) -1.14348
CAPN12 calpain 12 -1.14313
KLRC2 killer cell lectin-like receptor subfamily C, member 2 -1.1405
PCDHA4 protocadherin alpha 4 -1.13856
CD302 CD302 molecule -1.13842
WFDC10B WAP four-disulfide core domain 10B -1.13365
PCDHA13 protocadherin alpha 13 -1.13068
RAD9A RAD9 homolog A (S. pombe) -1.13039
ACHE acetylcholinesterase (Yt blood group) -1.13022
MAN2A2 mannosidase, alpha, class 2A, member 2 -1.12622
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) -1.12474
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.12134
OSR1 odd-skipped related transciption factor 1 -1.121
SLK STE20-like kinase -1.12075
DNTT DNA nucleotidylexotransferase -1.11562
TUBA3C tubulin, alpha 3c -1.11407
AP3M2 adaptor-related protein complex 3, mu 2 subunit -1.11071
SECISBP2L SECIS binding protein 2-like -1.10835
RHAG Rh-associated glycoprotein -1.108
PCDHA10 protocadherin alpha 10 -1.10728
OR51V1 olfactory receptor, family 51, subfamily V, member 1 -1.10555
INTS12 integrator complex subunit 12 -1.10339
UGDH UDP-glucose 6-dehydrogenase -1.10317
LRP1B low density lipoprotein receptor-related protein 1B -1.10296
SLC25A40 solute carrier family 25, member 40 -1.09997
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -1.09835
PCDHA2 protocadherin alpha 2 -1.09664
ACLY ATP citrate lyase -1.0933
ANXA1 annexin A1 -1.0927
ZNF707 zinc finger protein 707 -1.09095
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) -1.08956
FBXO3 F-box protein 3 -1.08751
ADCY2 adenylate cyclase 2 (brain) -1.08666
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -1.08528
S1PR5 sphingosine-1-phosphate receptor 5 -1.07994
DFNA5 deafness, autosomal dominant 5 -1.07915
GBA2 glucosidase, beta (bile acid) 2 -1.07417
ADCY7 adenylate cyclase 7 -1.07378
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 -1.06988
ADGRE5 adhesion G protein-coupled receptor E5 -1.06578
SRPRB signal recognition particle receptor, B subunit -1.06373
SRSF8 serine/arginine-rich splicing factor 8 -1.06112
DCLRE1B DNA cross-link repair 1B -1.05839
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 -1.05801
GPR141 G protein-coupled receptor 141 -1.05726
AIRE autoimmune regulator -1.05253
ZNF579 zinc finger protein 579 -1.05034
CLK1 CDC-like kinase 1 -1.04632
ARHGAP20 Rho GTPase activating protein 20 -1.04573
HLA-DMB major histocompatibility complex, class II, DM beta -1.04396
ZFP36L2 ZFP36 ring finger protein-like 2 -1.03583
AK1 adenylate kinase 1 -1.03398
TGIF2 TGFB-induced factor homeobox 2 -1.03364
MED30 mediator complex subunit 30 -1.03212
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 -1.03124
ZNF860 zinc finger protein 860 -1.02994
CNTRL centriolin -1.02694
ZNF281 zinc finger protein 281 -1.02461
C6ORF118 chromosome 6 open reading frame 118 -1.01201
POT1 protection of telomeres 1 -1.00974
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -1.00927
HIST1H4E histone cluster 1, H4e -1.00794
MDC1 mediator of DNA-damage checkpoint 1 -1.00722
IFT54 intraflagellar transport 54 -1.00692
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -1.00566
ABR active BCR-related -1.00492
RNF144B ring finger protein 144B -1.00441
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) -1.004