OPM2 Gene Set

Dataset DepMap CRISPR Gene Dependency
Category disease or phenotype associations
Type cell line
Description Plasma Cell Myeloma cell line (Cancer Dependency Map)
External Link https://depmap.org/portal/cell_line/ACH-000024
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Genes

670 gene knockdowns changing fitness of OPM2 relative to other cell lines from the DepMap CRISPR Gene Dependency Dataset.

Symbol Name Standardized Value
AHCYL2 adenosylhomocysteinase-like 2 12.7879
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 12.216
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 12.0596
FGFR3 fibroblast growth factor receptor 3 10.8844
ZBTB38 zinc finger and BTB domain containing 38 9.80591
SLC38A5 solute carrier family 38, member 5 9.6188
RAB9A RAB9A, member RAS oncogene family 9.52152
GADD45B growth arrest and DNA-damage-inducible, beta 9.18893
STMN1 stathmin 1 8.66571
GRIPAP1 GRIP1 associated protein 1 8.66455
BICRA BRD4 interacting chromatin remodeling complex associated protein 8.61771
TCF12 transcription factor 12 8.3601
MAP3K4 mitogen-activated protein kinase kinase kinase 4 8.14446
ZNF592 zinc finger protein 592 7.96606
CTBP1 C-terminal binding protein 1 7.90584
PDCD10 programmed cell death 10 7.81904
GFI1 growth factor independent 1 transcription repressor 7.71788
C2ORF80 chromosome 2 open reading frame 80 7.60533
PRDM1 PR domain containing 1, with ZNF domain 7.49683
KRIT1 KRIT1, ankyrin repeat containing 7.44576
HMG20B high mobility group 20B 7.37301
GLIS2 GLIS family zinc finger 2 7.24335
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 7.06701
ZMIZ2 zinc finger, MIZ-type containing 2 6.51549
PDCD2L programmed cell death 2-like 6.34916
ING2 inhibitor of growth family, member 2 6.34023
BAMBI BMP and activin membrane-bound inhibitor 6.19265
TMEM121 transmembrane protein 121 6.19154
ALG9 ALG9, alpha-1,2-mannosyltransferase 6.15279
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 6.10818
CCM2 cerebral cavernous malformation 2 6.09789
TCF3 transcription factor 3 6.05818
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 5.92702
RAB14 RAB14, member RAS oncogene family 5.88315
PGLYRP4 peptidoglycan recognition protein 4 5.86418
FNIP1 folliculin interacting protein 1 5.78268
IFT27 intraflagellar transport 27 5.709
GATAD2B GATA zinc finger domain containing 2B 5.69759
BRD9 bromodomain containing 9 5.65274
SNX27 sorting nexin family member 27 5.63919
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 5.6212
CHD7 chromodomain helicase DNA binding protein 7 5.57425
ADIPOR2 adiponectin receptor 2 5.53432
RNF212 ring finger protein 212 5.40389
RHOBTB3 Rho-related BTB domain containing 3 5.39715
IKZF1 IKAROS family zinc finger 1 (Ikaros) 5.39153
ARHGAP45 Rho GTPase activating protein 45 5.38491
SPHK2 sphingosine kinase 2 5.34386
CRIP2 cysteine-rich protein 2 5.25377
IRF2 interferon regulatory factor 2 5.25265
IGSF9 immunoglobulin superfamily, member 9 5.2285
SMAD7 SMAD family member 7 5.21127
GBA glucosidase, beta, acid 5.19667
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 5.18747
OAZ1 ornithine decarboxylase antizyme 1 5.17605
CCL13 chemokine (C-C motif) ligand 13 5.15797
BMI1 BMI1 proto-oncogene, polycomb ring finger 5.14822
ARID3B AT rich interactive domain 3B (BRIGHT-like) 5.13519
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 5.12638
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted 5.12042
LCE3B late cornified envelope 3B 5.11
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 5.05734
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35 5.02064
GAS6 growth arrest-specific 6 5.0065
POU2AF1 POU class 2 associating factor 1 4.96206
METTL13 methyltransferase like 13 4.93675
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 4.89026
CDYL chromodomain protein, Y-like 4.83758
THAP4 THAP domain containing 4 4.82468
UHRF1BP1L UHRF1 binding protein 1-like 4.81949
SPATA2L spermatogenesis associated 2-like 4.80209
MUC1 mucin 1, cell surface associated 4.78005
RNF44 ring finger protein 44 4.74691
MED13L mediator complex subunit 13-like 4.74595
CSRNP1 cysteine-serine-rich nuclear protein 1 4.72502
ZNF800 zinc finger protein 800 4.72356
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 4.59149
PLAGL2 pleiomorphic adenoma gene-like 2 4.58995
FBXW2 F-box and WD repeat domain containing 2 4.57697
ZNF672 zinc finger protein 672 4.55128
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 4.54045
TOR1B torsin family 1, member B (torsin B) 4.52681
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 4.50451
SGPL1 sphingosine-1-phosphate lyase 1 4.48414
DGAT1 diacylglycerol O-acyltransferase 1 4.47316
POLM polymerase (DNA directed), mu 4.471
CUX1 cut-like homeobox 1 4.45897
OR2M7 olfactory receptor, family 2, subfamily M, member 7 4.43798
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 4.43719
PLEKHO2 pleckstrin homology domain containing, family O member 2 4.43272
IRS1 insulin receptor substrate 1 4.4132
ALG12 ALG12, alpha-1,6-mannosyltransferase 4.39637
GSS glutathione synthetase 4.38618
VPS9D1 VPS9 domain containing 1 4.37865
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 4.36848
AFF1 AF4/FMR2 family, member 1 4.35548
ZMYND11 zinc finger, MYND-type containing 11 4.34664
DOK3 docking protein 3 4.32716
LCE3C late cornified envelope 3C 4.31924
UBALD2 UBA-like domain containing 2 4.2541
CCND2 cyclin D2 4.2467
SERTAD2 SERTA domain containing 2 4.24534
DNASE1 deoxyribonuclease I 4.23704
UNC79 unc-79 homolog (C. elegans) 4.22942
CORO7 coronin 7 4.22329
MSL2 male-specific lethal 2 homolog (Drosophila) 4.19836
ANGEL2 angel homolog 2 (Drosophila) 4.19053
ARHGAP30 Rho GTPase activating protein 30 4.18375
MAPK6 mitogen-activated protein kinase 6 4.15312
WDR20 WD repeat domain 20 4.12915
GPR132 G protein-coupled receptor 132 4.12218
CLPSL1 colipase-like 1 4.11017
SPIRE2 spire-type actin nucleation factor 2 4.10857
XPO4 exportin 4 4.09969
EBI3 Epstein-Barr virus induced 3 4.09809
ZNF281 zinc finger protein 281 4.09573
SLC25A42 solute carrier family 25, member 42 4.0734
NOXRED1 NADP-dependent oxidoreductase domain containing 1 4.06691
TRAP1 TNF receptor-associated protein 1 4.03711
CDK5RAP2 CDK5 regulatory subunit associated protein 2 4.02971
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.01357
HP1BP3 heterochromatin protein 1, binding protein 3 4.00727
STEAP3 STEAP family member 3, metalloreductase 3.98925
METTL11B methyltransferase like 11B 3.96542
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase 3.95868
IRF4 interferon regulatory factor 4 3.913
TAOK1 TAO kinase 1 3.90424
VDAC2 voltage-dependent anion channel 2 3.89594
ATRX alpha thalassemia/mental retardation syndrome X-linked 3.88855
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 3.88728
CPLX2 complexin 2 3.81138
TMOD3 tropomodulin 3 (ubiquitous) 3.79608
ITLN2 intelectin 2 3.77465
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 3.76679
USP11 ubiquitin specific peptidase 11 3.73204
AHNAK2 AHNAK nucleoprotein 2 3.71807
LRRC74A leucine rich repeat containing 74A 3.71792
C1ORF21 chromosome 1 open reading frame 21 3.71319
ARHGAP1 Rho GTPase activating protein 1 3.70548
MAPK14 mitogen-activated protein kinase 14 3.69901
ARRB2 arrestin, beta 2 3.69826
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 3.69183
MED13 mediator complex subunit 13 3.68158
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 3.67446
PRR14 proline rich 14 3.67299
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 3.66783
SMYD4 SET and MYND domain containing 4 3.65849
CCDC47 coiled-coil domain containing 47 3.65307
DPH5 diphthamide biosynthesis 5 3.64217
GCLC glutamate-cysteine ligase, catalytic subunit 3.63321
REEP4 receptor accessory protein 4 3.63157
TMEM222 transmembrane protein 222 3.62952
RING1 ring finger protein 1 3.62232
CLDN6 claudin 6 3.62223
NCBP3 nuclear cap binding subunit 3 3.62172
RP9 retinitis pigmentosa 9 (autosomal dominant) 3.60187
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 3.58818
SUSD3 sushi domain containing 3 3.58341
HTT huntingtin 3.57873
FRS2 fibroblast growth factor receptor substrate 2 3.56116
CREBBP CREB binding protein 3.5536
ZNF581 zinc finger protein 581 3.55108
RUNX1 runt-related transcription factor 1 3.54426
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 3.53414
FICD FIC domain containing 3.51755
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 3.51166
RTL8C retrotransposon Gag like 8C 3.50904
KREMEN2 kringle containing transmembrane protein 2 3.50721
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 3.49431
AIP aryl hydrocarbon receptor interacting protein 3.49391
ASB7 ankyrin repeat and SOCS box containing 7 3.47863
TMEM251 transmembrane protein 251 3.47035
PHF21A PHD finger protein 21A 3.46151
PGLS 6-phosphogluconolactonase 3.45906
GLP2R glucagon-like peptide 2 receptor 3.4556
USF1 upstream transcription factor 1 3.44083
JAGN1 jagunal homolog 1 (Drosophila) 3.43464
C4ORF46 chromosome 4 open reading frame 46 3.41631
BICDL2 BICD family like cargo adaptor 2 3.41361
DGKQ diacylglycerol kinase, theta 110kDa 3.40586
C11ORF58 chromosome 11 open reading frame 58 3.3939
EML1 echinoderm microtubule associated protein like 1 3.38784
DPEP1 dipeptidase 1 (renal) 3.38447
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 3.37144
DOT1L DOT1-like histone H3K79 methyltransferase 3.354
TMEM80 transmembrane protein 80 3.35173
TOP2B topoisomerase (DNA) II beta 180kDa 3.34956
GUCY1B3 guanylate cyclase 1, soluble, beta 3 3.34635
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 3.34471
CLPTM1 cleft lip and palate associated transmembrane protein 1 3.34312
COMMD1 copper metabolism (Murr1) domain containing 1 3.33591
MPDU1 mannose-P-dolichol utilization defect 1 3.33327
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 3.32941
CUL4A cullin 4A 3.32829
LRP10 low density lipoprotein receptor-related protein 10 3.32611
ANKLE1 ankyrin repeat and LEM domain containing 1 3.32115
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 3.32034
ALG3 ALG3, alpha-1,3- mannosyltransferase 3.30683
CBX3 chromobox homolog 3 3.3031
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 3.30273
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1 3.30029
HUS1B HUS1 checkpoint homolog b (S. pombe) 3.28933
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 3.28885
CLK3 CDC-like kinase 3 3.28866
IFRD2 interferon-related developmental regulator 2 3.26677
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 3.26548
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 3.21915
OR1K1 olfactory receptor, family 1, subfamily K, member 1 3.21708
RTP5 receptor (chemosensory) transporter protein 5 (putative) 3.2166
P4HB prolyl 4-hydroxylase, beta polypeptide 3.20886
SLCO5A1 solute carrier organic anion transporter family, member 5A1 3.20115
HID1 HID1 domain containing 3.18741
WASHC5 WASH complex subunit 5 3.18665
TSACC TSSK6 activating co-chaperone 3.18421
TUBB3 tubulin, beta 3 class III 3.17884
C22ORF31 chromosome 22 open reading frame 31 3.17689
BRPF3 bromodomain and PHD finger containing, 3 3.16579
ARMCX6 armadillo repeat containing, X-linked 6 3.16313
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 3.1599
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 3.15907
UBALD1 UBA-like domain containing 1 3.15481
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 3.15332
DNAL1 dynein, axonemal, light chain 1 3.14409
MTMR1 myotubularin related protein 1 3.1437
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) 3.13664
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 3.12296
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 3.12095
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae) 3.11538
ARID3A AT rich interactive domain 3A (BRIGHT-like) 3.11444
THRA thyroid hormone receptor, alpha 3.1136
SLTM SAFB-like, transcription modulator 3.11204
DENND1B DENN/MADD domain containing 1B 3.10821
PPP4R4 protein phosphatase 4, regulatory subunit 4 3.10088
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 3.10014
PRAMEF14 PRAME family member 14 3.09156
LARP4B La ribonucleoprotein domain family, member 4B 3.09038
FCRL3 Fc receptor-like 3 3.07896
OR2T8 olfactory receptor, family 2, subfamily T, member 8 3.07097
PPCDC phosphopantothenoylcysteine decarboxylase 3.06558
OR52E2 olfactory receptor, family 52, subfamily E, member 2 3.06426
TRPV4 transient receptor potential cation channel, subfamily V, member 4 3.06144
MTFR1 mitochondrial fission regulator 1 3.06105
LRRC46 leucine rich repeat containing 46 3.0607
RFX5 regulatory factor X, 5 (influences HLA class II expression) 3.05943
USP25 ubiquitin specific peptidase 25 3.05699
TBC1D5 TBC1 domain family, member 5 3.05612
METTL26 methyltransferase like 26 3.05306
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.04817
TSPYL6 TSPY-like 6 3.04643
GBX1 gastrulation brain homeobox 1 3.04341
VAC14 Vac14 homolog (S. cerevisiae) 3.03519
HCAR1 hydroxycarboxylic acid receptor 1 3.03168
AP3B1 adaptor-related protein complex 3, beta 1 subunit 3.03162
CR1L complement component (3b/4b) receptor 1-like 3.03154
KDM4B lysine (K)-specific demethylase 4B 3.02942
PLD6 phospholipase D family, member 6 3.02028
PROSER1 proline and serine rich 1 3.01692
KRTCAP2 keratinocyte associated protein 2 3.01343
CLIC6 chloride intracellular channel 6 3.01298
IL6R interleukin 6 receptor 3.00795
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 2.99356
LCE3A late cornified envelope 3A 2.98868
ELF2 E74-like factor 2 (ets domain transcription factor) 2.97665
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 2.96815
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9 2.96083
SAP30 Sin3A-associated protein, 30kDa 2.95172
ZNF692 zinc finger protein 692 2.94949
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2.94758
ZNF619 zinc finger protein 619 2.94211
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.92985
TENT4B terminal nucleotidyltransferase 4B 2.92629
AARSD1 alanyl-tRNA synthetase domain containing 1 2.91889
CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2.91077
THBS3 thrombospondin 3 2.90489
GUCY2F guanylate cyclase 2F, retinal 2.89994
KDM5C lysine (K)-specific demethylase 5C 2.89828
ZNF200 zinc finger protein 200 2.89612
ZNF425 zinc finger protein 425 2.89061
CDK10 cyclin-dependent kinase 10 2.88306
CDK5RAP3 CDK5 regulatory subunit associated protein 3 2.88083
PLEKHN1 pleckstrin homology domain containing, family N member 1 2.87821
SPAST spastin 2.87761
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 2.87233
APOA2 apolipoprotein A-II 2.86868
PUS10 pseudouridylate synthase 10 2.86734
ZNF625 zinc finger protein 625 2.86461
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 2.85191
EVI5 ecotropic viral integration site 5 2.85173
ZNF18 zinc finger protein 18 2.84947
INF2 inverted formin, FH2 and WH2 domain containing 2.8456
MOB3A MOB kinase activator 3A 2.84419
CCDC22 coiled-coil domain containing 22 2.83753
EIF3K eukaryotic translation initiation factor 3, subunit K 2.83471
DPY19L1 dpy-19-like 1 (C. elegans) 2.83195
LEMD3 LEM domain containing 3 2.83106
FSCN2 fascin actin-bundling protein 2, retinal 2.82424
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.82409
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.82233
VRTN vertebrae development associated 2.81777
TIPE3 TNF alpha induced protein 8 like 3 2.81742
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 2.81737
IFNA1 interferon, alpha 1 2.81689
PIANP PILR alpha associated neural protein 2.8151
ZFP1 ZFP1 zinc finger protein 2.81034
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.80913
PRR32 proline rich 32 2.80025
PUM3 pumilio RNA binding family member 3 2.79895
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.79603
ANO10 anoctamin 10 2.79096
TUBA3E tubulin, alpha 3e 2.79024
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 2.78975
MTMR14 myotubularin related protein 14 2.77931
CPOX coproporphyrinogen oxidase 2.77545
ODR4 odr-4 GPCR localization factor homolog 2.76577
BDNF brain-derived neurotrophic factor 2.76556
ZNF580 zinc finger protein 580 2.76072
MIB1 mindbomb E3 ubiquitin protein ligase 1 2.75676
KDM4A lysine (K)-specific demethylase 4A 2.75446
MED23 mediator complex subunit 23 2.75394
TLE3 transducin-like enhancer of split 3 2.75359
UROS uroporphyrinogen III synthase 2.74067
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 2.73978
UBE4B ubiquitination factor E4B 2.73819
CALHM2 calcium homeostasis modulator 2 2.73808
WDR86 WD repeat domain 86 2.73482
LYPD3 LY6/PLAUR domain containing 3 2.72918
AK2 adenylate kinase 2 2.72135
RBM3 RNA binding motif (RNP1, RRM) protein 3 2.72094
BRWD1 bromodomain and WD repeat domain containing 1 2.71992
CLK1 CDC-like kinase 1 2.71865
CASKIN1 CASK interacting protein 1 2.71559
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 2.71372
SCLY selenocysteine lyase 2.70815
KDM4C lysine (K)-specific demethylase 4C 2.70692
ZNF398 zinc finger protein 398 2.70391
GCLM glutamate-cysteine ligase, modifier subunit 2.7035
OAT ornithine aminotransferase 2.69408
POU2F1 POU class 2 homeobox 1 2.69084
RGL3 ral guanine nucleotide dissociation stimulator-like 3 2.69081
KDSR 3-ketodihydrosphingosine reductase 2.689
CPZ carboxypeptidase Z 2.68841
PRRT4 proline-rich transmembrane protein 4 2.68574
FAM204A family with sequence similarity 204, member A 2.68271
ABLIM3 actin binding LIM protein family, member 3 2.68154
SPATA33 spermatogenesis associated 33 2.6813
ZNF783 zinc finger family member 783 2.67132
SH3BP2 SH3-domain binding protein 2 2.66298
TRIM28 tripartite motif containing 28 2.66164
ZNF746 zinc finger protein 746 2.65621
MBNL1 muscleblind-like splicing regulator 1 2.65443
CHURC1 churchill domain containing 1 2.65378
RBMS2 RNA binding motif, single stranded interacting protein 2 2.6533
PAQR4 progestin and adipoQ receptor family member IV 2.65141
ZMYND19 zinc finger, MYND-type containing 19 2.64847
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2.64061
GPR179 G protein-coupled receptor 179 2.63686
ZNF276 zinc finger protein 276 2.63348
LRRC14 leucine rich repeat containing 14 2.63341
NBL1 neuroblastoma 1, DAN family BMP antagonist 2.63338
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.62905
ZNF740 zinc finger protein 740 2.62651
RUNX2 runt-related transcription factor 2 2.62443
GLS glutaminase 2.62244
CDR2 cerebellar degeneration-related protein 2, 62kDa 2.61834
PBRM1 polybromo 1 2.61337
MANF mesencephalic astrocyte-derived neurotrophic factor 2.61307
EPHB6 EPH receptor B6 2.60882
TMEM62 transmembrane protein 62 2.60874
CBFB core-binding factor, beta subunit 2.60871
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.60556
SSC5D scavenger receptor cysteine rich family, 5 domains 2.60479
GATSL3 GATS protein-like 3 2.59692
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 2.5962
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 2.59064
PER2 period circadian clock 2 2.59037
FAM161A family with sequence similarity 161, member A 2.58912
EMID1 EMI domain containing 1 2.57844
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 2.57811
RANBP3 RAN binding protein 3 2.57667
CTNNBIP1 catenin, beta interacting protein 1 2.57441
S1PR4 sphingosine-1-phosphate receptor 4 2.56807
OR2V2 olfactory receptor, family 2, subfamily V, member 2 2.56773
PRDX2 peroxiredoxin 2 2.56754
ZBED4 zinc finger, BED-type containing 4 2.56458
TWSG1 twisted gastrulation BMP signaling modulator 1 2.56442
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.55647
MIER3 mesoderm induction early response 1, family member 3 2.55479
VWCE von Willebrand factor C and EGF domains 2.55098
DAW1 dynein assembly factor with WDR repeat domains 1 2.54626
OR1F1 olfactory receptor, family 1, subfamily F, member 1 2.54563
HPS4 Hermansky-Pudlak syndrome 4 2.54388
DIS3L DIS3 like exosome 3'-5' exoribonuclease 2.53827
EIF3L eukaryotic translation initiation factor 3, subunit L 2.53676
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 2.53357
PHF10 PHD finger protein 10 2.53249
OR7G2 olfactory receptor, family 7, subfamily G, member 2 2.53066
C19ORF57 chromosome 19 open reading frame 57 2.52998
SAFB2 scaffold attachment factor B2 2.52177
L3MBTL3 l(3)mbt-like 3 (Drosophila) 2.51478
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.51199
BAG5 BCL2-associated athanogene 5 2.51152
FNDC8 fibronectin type III domain containing 8 2.51018
FURIN furin (paired basic amino acid cleaving enzyme) 2.50778
CPN2 carboxypeptidase N, polypeptide 2 2.50637
ELF1 E74-like factor 1 (ets domain transcription factor) 2.50279
MED15 mediator complex subunit 15 2.50191
SOWAHB sosondowah ankyrin repeat domain family member B 2.50171
RAB40C RAB40C, member RAS oncogene family 2.50098
NT5DC3 5'-nucleotidase domain containing 3 2.50083
KCTD5 potassium channel tetramerization domain containing 5 2.49895
ZBTB2 zinc finger and BTB domain containing 2 2.4978
OR56B1 olfactory receptor, family 56, subfamily B, member 1 2.49746
HNF1B HNF1 homeobox B 2.4961
SPANXN5 SPANX family, member N5 2.49328
SOS1 son of sevenless homolog 1 (Drosophila) 2.49129
RAB26 RAB26, member RAS oncogene family 2.49112
DAXX death-domain associated protein 2.4871
ZNF185 zinc finger protein 185 (LIM domain) 2.48616
RPH3A rabphilin 3A 2.48579
OR9G1 olfactory receptor, family 9, subfamily G, member 1 2.48543
ALS2CL ALS2 C-terminal like 2.48171
WDFY2 WD repeat and FYVE domain containing 2 2.47734
OR2T5 olfactory receptor, family 2, subfamily T, member 5 2.47617
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.47535
PGLYRP3 peptidoglycan recognition protein 3 2.47404
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 2.47344
ZNF333 zinc finger protein 333 2.47303
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 2.47274
AOC2 amine oxidase, copper containing 2 (retina-specific) 2.47128
OR56A1 olfactory receptor, family 56, subfamily A, member 1 2.46853
HFE2 hemochromatosis type 2 (juvenile) 2.46801
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 2.46681
UNK unkempt family zinc finger 2.46491
OR4D1 olfactory receptor, family 4, subfamily D, member 1 2.46472
PRDX3 peroxiredoxin 3 2.46277
VANGL2 VANGL planar cell polarity protein 2 2.46063
FAM160A1 family with sequence similarity 160, member A1 2.45625
FKBP2 FK506 binding protein 2, 13kDa 2.45412
ZNF142 zinc finger protein 142 2.4532
C19ORF73 chromosome 19 open reading frame 73 2.45194
URGCP upregulator of cell proliferation 2.4505
EFNA4 ephrin-A4 2.44979
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 2.44853
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.4481
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.44499
MED16 mediator complex subunit 16 2.44337
TMEM161A transmembrane protein 161A 2.44285
TBX19 T-box 19 2.44273
DUSP23 dual specificity phosphatase 23 2.44054
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.4316
OR2G6 olfactory receptor, family 2, subfamily G, member 6 2.43132
RHOT1 ras homolog family member T1 2.43112
AHR aryl hydrocarbon receptor 2.42928
RCSD1 RCSD domain containing 1 2.42828
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.42696
RCC2 regulator of chromosome condensation 2 2.4203
CNGA2 cyclic nucleotide gated channel alpha 2 2.41912
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.41843
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.41356
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2.41354
USP3 ubiquitin specific peptidase 3 2.41234
C5ORF63 chromosome 5 open reading frame 63 2.41077
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 2.41026
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 2.40918
GAS8 growth arrest-specific 8 2.40803
TLDC2 TBC/LysM-associated domain containing 2 2.40505
FCRLB Fc receptor-like B 2.40012
R3HCC1L R3H domain and coiled-coil containing 1-like 2.39832
IGSF8 immunoglobulin superfamily, member 8 2.3952
SS18 synovial sarcoma translocation, chromosome 18 2.39504
FAM71F2 family with sequence similarity 71, member F2 2.39335
DIDO1 death inducer-obliterator 1 2.38968
WDR83OS WD repeat domain 83 opposite strand 2.38432
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6 2.38031
MTF2 metal response element binding transcription factor 2 2.37995
LENG9 leukocyte receptor cluster (LRC) member 9 2.37929
CHRM2 cholinergic receptor, muscarinic 2 2.37443
RPL41 ribosomal protein L41 2.37386
BATF basic leucine zipper transcription factor, ATF-like 2.37345
TMEM216 transmembrane protein 216 2.37205
GOLGA6B golgin A6 family, member B 2.37201
CBR4 carbonyl reductase 4 2.36994
ZNF835 zinc finger protein 835 2.36804
PCGF1 polycomb group ring finger 1 2.3673
KLHDC10 kelch domain containing 10 2.36257
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 2.36153
COMMD10 COMM domain containing 10 2.35994
PITX1 paired-like homeodomain 1 2.35793
SRRD SRR1 domain containing 2.35606
CCDC132 coiled-coil domain containing 132 2.35588
BGLAP bone gamma-carboxyglutamate (gla) protein 2.35235
LACTB lactamase, beta 2.35216
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 2.3521
C14ORF79 chromosome 14 open reading frame 79 2.34958
RNF166 ring finger protein 166 2.34932
SHE Src homology 2 domain containing E 2.34444
PDZK1 PDZ domain containing 1 2.338
YIPF5 Yip1 domain family, member 5 2.33785
TADA2B transcriptional adaptor 2B 2.33675
CEP170B centrosomal protein 170B 2.33017
AAMDC adipogenesis associated, Mth938 domain containing 2.32921
CLIP1 CAP-GLY domain containing linker protein 1 2.32222
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.31717
HPSE heparanase 2.31683
UBTD2 ubiquitin domain containing 2 2.31389
CRH corticotropin releasing hormone 2.30983
SIK2 salt-inducible kinase 2 2.30815
OR5V1 olfactory receptor, family 5, subfamily V, member 1 2.30341
GAGE12H G antigen 12H 2.3034
CCNC cyclin C 2.30319
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 2.30277
HMOX2 heme oxygenase 2 2.3021
RSF1 remodeling and spacing factor 1 2.30107
ZNF638 zinc finger protein 638 2.30001
ZFYVE26 zinc finger, FYVE domain containing 26 2.29372
HIST1H2BO histone cluster 1, H2bo 2.28981
RND2 Rho family GTPase 2 2.28621
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.28446
FRG2B FSHD region gene 2 family, member B 2.28271
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.28028
DENND11 DENN domain containing 11 2.27769
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.27554
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.27442
TRIM46 tripartite motif containing 46 2.26889
AEBP1 AE binding protein 1 2.26665
RNF151 ring finger protein 151 2.26573
DBNL drebrin-like 2.26104
DPH2 DPH2 homolog (S. cerevisiae) 2.25389
CHKA choline kinase alpha 2.2519
PRKCQ protein kinase C, theta 2.25178
HIST1H2BF histone cluster 1, H2bf 2.24497
COMMD3 COMM domain containing 3 2.24375
ZFP57 ZFP57 zinc finger protein 2.24047
KDM3B lysine (K)-specific demethylase 3B 2.23894
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.23886
FLCN folliculin 2.23185
TMSB15A thymosin beta 15a 2.22967
MAP9 microtubule-associated protein 9 2.22527
HDAC2 histone deacetylase 2 2.22257
ARMC9 armadillo repeat containing 9 2.22062
C17ORF67 chromosome 17 open reading frame 67 2.2203
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 2.21767
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.21745
IFNA21 interferon, alpha 21 2.21422
FLNC filamin C, gamma 2.21242
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 2.21224
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 2.20921
FAM92B family with sequence similarity 92, member B 2.20626
ARL8B ADP-ribosylation factor-like 8B 2.20584
ITGA6 integrin, alpha 6 2.20517
ATXN7 ataxin 7 2.20454
STK11 serine/threonine kinase 11 2.20338
MTMR4 myotubularin related protein 4 2.2028
ZMYND8 zinc finger, MYND-type containing 8 2.20253
RHPN1 rhophilin, Rho GTPase binding protein 1 2.2004
STK25 serine/threonine kinase 25 2.19748
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.19596
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.19517
C14ORF180 chromosome 14 open reading frame 180 2.19448
SULF1 sulfatase 1 2.19165
SYT11 synaptotagmin XI 2.19046
TTC37 tetratricopeptide repeat domain 37 2.19024
UNG uracil-DNA glycosylase 2.18944
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 2.18942
OR13F1 olfactory receptor, family 13, subfamily F, member 1 2.18888
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.17646
SETD1B SET domain containing 1B 2.17293
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 2.17196
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.16495
CATSPER4 cation channel, sperm associated 4 2.16489
ANKRD16 ankyrin repeat domain 16 2.16382
GLMN glomulin, FKBP associated protein 2.16195
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.15826
ZNF180 zinc finger protein 180 2.15606
AMZ1 archaelysin family metallopeptidase 1 2.15584
FOXK1 forkhead box K1 2.15536
TMED8 transmembrane emp24 protein transport domain containing 8 2.15318
PRLH prolactin releasing hormone 2.1527
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 2.15244
FAM71A family with sequence similarity 71, member A 2.14843
ANXA13 annexin A13 2.14782
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 2.14068
S100A12 S100 calcium binding protein A12 2.13302
IZUMO4 IZUMO family member 4 2.12833
RNF222 ring finger protein 222 2.12598
FKBP1A FK506 binding protein 1A, 12kDa 2.12477
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.12418
OSER1 oxidative stress responsive serine-rich 1 2.1225
CBY3 chibby homolog 3 (Drosophila) 2.12226
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 2.12051
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 2.11848
ZNF683 zinc finger protein 683 2.11607
CPN1 carboxypeptidase N, polypeptide 1 2.11562
TSKS testis-specific serine kinase substrate 2.11475
HDC histidine decarboxylase 2.11346
PAGE4 P antigen family, member 4 (prostate associated) 2.1101
CYB5R2 cytochrome b5 reductase 2 2.10932
HK2 hexokinase 2 2.1084
APH1B APH1B gamma secretase subunit 2.10717
ANKFY1 ankyrin repeat and FYVE domain containing 1 2.10505
ATXN7L3 ataxin 7-like 3 2.10441
TLE2 transducin-like enhancer of split 2 2.10342
ATPSCKMT ATP synthase c subunit lysine N-methyltransferase 2.10196
VTA1 vesicle (multivesicular body) trafficking 1 2.10125
PGAP1 post-GPI attachment to proteins 1 2.10105
DAND5 DAN domain family member 5, BMP antagonist 2.10075
FBXO2 F-box protein 2 2.10049
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase 2.09791
ZNF584 zinc finger protein 584 2.09309
FAM228A family with sequence similarity 228, member A 2.09294
NEUROD2 neuronal differentiation 2 2.08933
FRMD1 FERM domain containing 1 2.08734
KLF13 Kruppel-like factor 13 2.08493
DPH1 diphthamide biosynthesis 1 2.08298
ZC3H10 zinc finger CCCH-type containing 10 2.08098
OR2M4 olfactory receptor, family 2, subfamily M, member 4 2.08057
DIO3 deiodinase, iodothyronine, type III 2.07844
FKBP9 FK506 binding protein 9, 63 kDa 2.07528
LTBP2 latent transforming growth factor beta binding protein 2 2.07441
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2.07422
FAM193B family with sequence similarity 193, member B 2.074
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 2.07137
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 2.06941
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.06918
HPS6 Hermansky-Pudlak syndrome 6 2.06393
USP22 ubiquitin specific peptidase 22 2.06382
CCDC93 coiled-coil domain containing 93 2.06002
UFSP2 UFM1-specific peptidase 2 2.0578
PURA purine-rich element binding protein A 2.05521
TH tyrosine hydroxylase 2.05507
FBXO21 F-box protein 21 2.05361
PHC3 polyhomeotic homolog 3 (Drosophila) 2.05348
COMMD7 COMM domain containing 7 2.0526
PRAMEF20 PRAME family member 20 2.04957
OR2H2 olfactory receptor, family 2, subfamily H, member 2 2.04793
ESPNL espin-like 2.04707
PMM2 phosphomannomutase 2 2.04131
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.03955
SCUBE3 signal peptide, CUB domain, EGF-like 3 2.03922
DPH7 diphthamide biosynthesis 7 2.03458
DUOXA1 dual oxidase maturation factor 1 2.03221
NES nestin 2.03214
OR51I1 olfactory receptor, family 51, subfamily I, member 1 2.03002
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.02941
SERTAD1 SERTA domain containing 1 2.02884
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 2.02655
C1ORF64 chromosome 1 open reading frame 64 2.02638
FLT4 fms-related tyrosine kinase 4 2.02603
CCDC88B coiled-coil domain containing 88B 2.02544
ZNF287 zinc finger protein 287 2.02442
CLRN1 clarin 1 2.02234
USP43 ubiquitin specific peptidase 43 2.02179
MRGPRE MAS-related GPR, member E 2.02104
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.01736
TNIP2 TNFAIP3 interacting protein 2 2.01586
SPTB spectrin, beta, erythrocytic 2.01574
MYLK4 myosin light chain kinase family, member 4 2.01553
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.01429
ERG28 ergosterol biosynthesis 28 homolog 2.01327
NSD3 nuclear receptor binding SET domain protein 3 2.01121
PRSS27 protease, serine 27 2.01115
TLE6 transducin-like enhancer of split 6 2.01096
RAD23A RAD23 homolog A (S. cerevisiae) 2.0106
CNBP CCHC-type zinc finger, nucleic acid binding protein 2.00875
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 2.00809
TMEM59L transmembrane protein 59-like 2.00801
PRAF2 PRA1 domain family, member 2 2.00598
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.00467
KIAA0895 KIAA0895 2.00406
STON1 stonin 1 2.00343